Multiple Sclerosis

Clinical trials recruiting in Australia for Multiple Sclerosis, as the public registries list them.

Also called: MS; Disseminated sclerosis

Sources: ClinicalTrials.gov, ISRCTN registry, MedlinePlus Checked: 15 October 2026 Not medical advice

At a glance

14 trials recruiting in Australia

5 states or territories with a listed site

1 started recruiting in the last 30 days

636 trials recruiting overseas

15 October 2026 date last checked

Where the trials are

Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.

Trials for Multiple Sclerosis

14 of 14 trials shown.

This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.

  • Recruiting Phase 3

    Phase 3 study for people with Multiple Sclerosis

    Where No Australian site is listed on the record.
    Who can join Age Not stated. Sex See the criteria below. Healthy volunteers See the criteria below.
    Sponsor University College London
    Timeline
    Started 18 January 2023 Today 16 October 2026 Estimated completion 31 December 2028

    ISRCTN14048364 · Checked 11 October 2026

  • Recruiting Phase 1

    Phase 1 study for people with Multiple Sclerosis

    Where
    • Nucleus Network, Herston (QLD) — Recruiting
    Who can join Age 18 Years to 55 Years. Sex Male participants only. Healthy volunteers Accepted.
    Sponsor Inventage Lab., Inc.
    Timeline
    Started 11 September 2024 Today 16 October 2026 Estimated completion 30 December 2025

    Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.

    NCT05620940 · Checked 11 October 2026

  • Recruiting Not a phased study

    Study for people with Multiple Sclerosis

    Where
    • Austin Hospital, Heidelberg (VIC) — Recruiting
    Who can join Age child, adult, older adult. Sex Female participants only. Healthy volunteers Not accepted.
    Sponsor Biogen
    Timeline
    Started 27 October 2023 Today 16 October 2026 Estimated completion 6 July 2032

    NCT05658497 · Checked 11 October 2026

  • Recruiting Phase 3

    Phase 3 study for people with Multiple Sclerosis

    Where
    • Royal Children's Hospital, Melbourne (VIC) — Recruiting
    Who can join Age 10 Years to 17 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Bristol-Myers Squibb
    Timeline
    Started 8 April 2025 Today 16 October 2026 Estimated completion 11 April 2031

    NCT06408259 · Checked 11 October 2026

  • Recruiting Phase 2

    Phase 2 study for people with Multiple Sclerosis

    Where
    • University of the Sunshine Coast Clinical Trials, Birtinya (QLD) — Recruiting
    Who can join Age 18 Years to 55 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor ModernaTX, Inc.
    Timeline
    Started 16 April 2025 Today 16 October 2026 Estimated completion 8 January 2029

    NCT06735248 · Checked 11 October 2026

  • Recruiting Phase 2

    Phase 2 study for people with Multiple Sclerosis

    Where
    • John Hunter Hospital, Newcastle (NSW) — Recruiting
    • University of Sydney - Brain and Mind Research Institute (BMRI), Sydney (NSW) — Recruiting
    • Centre for Neuroscience Innovation, Kent Town (SA) — Recruiting
    • Box Hill Hospital, Box Hill (VIC) — Recruiting
    • Austin Health, Heidelberg (VIC) — Recruiting
    • The Royal Melbourne Hospital, Parkville (VIC) — Recruiting
    • Perron Institute, Nedlands (WA) — Recruiting
    Who can join Age 18 Years to 70 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Celgene
    Timeline
    Started 5 June 2025 Today 16 October 2026 Estimated completion 26 May 2027

    NCT06782490 · Checked 11 October 2026

  • Recruiting Phase 3

    Phase 3 study for people with Multiple Sclerosis

    Where
    • Novartis Investigative Site, Melbourne (VIC) — Recruiting
    • Novartis Investigative Site, Parkville (VIC) — Recruiting
    • Novartis Investigative Site, Liverpool (NSW) — Withdrawn
    • Novartis Investigative Site, St Leonards (NSW) — Recruiting
    Who can join Age 40 Years to 70 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Novartis Pharmaceuticals
    Timeline
    Started 23 June 2025 Today 16 October 2026 Estimated completion 25 July 2029

    NCT06846281 · Checked 11 October 2026

  • Recruiting Phase 2

    Phase 2 study for people with Multiple Sclerosis

    Where
    • CMAX, Adelaide (SA) — Recruiting
    Who can join Age 18 Years to 65 Years. Sex Anyone, regardless of sex. Healthy volunteers Accepted.
    Sponsor Vidya Therapeutics Inc
    Timeline
    Started 1 August 2025 Today 16 October 2026 Estimated completion 30 October 2026

    NCT07085507 · Checked 11 October 2026

  • Recruiting Phase 1

    Phase 1 study for people with Multiple Sclerosis

    Where
    • Research Site, Liverpool (NSW) — Not yet recruiting
    • Research Site, Melbourne (VIC) — Recruiting
    • Research Site, Melbourne (VIC) — Not yet recruiting
    • Research Site, Waratah (NSW) — Not yet recruiting
    Who can join Age 18 Years to 60 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor AstraZeneca
    Timeline
    Started 9 December 2025 Today 16 October 2026 Estimated completion 12 December 2028

    NCT07224373 · Checked 11 October 2026

  • Recruiting Phase 3

    Phase 3 study for people with Multiple Sclerosis

    Where
    • Novartis Investigative Site, Kogarah (NSW) — Recruiting
    • Novartis Investigative Site, New Lambton Heights (NSW) — Recruiting
    • Novartis Investigative Site, Westmead (NSW) — Recruiting
    • Novartis Investigative Site, Clayton (VIC) — Recruiting
    • Novartis Investigative Site, Heidelberg (VIC) — Recruiting
    • Novartis Investigative Site, Murdoch (WA) — Recruiting
    • Novartis Investigative Site, Southport (QLD) — Recruiting
    Who can join Age 18 Years to 65 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Novartis Pharmaceuticals
    Timeline
    Started 11 November 2025 Today 16 October 2026 Estimated completion 3 December 2030

    NCT07225504 · Checked 15 October 2026

  • Recruiting Phase 2

    Phase 2 study for people with Multiple Sclerosis

    Where
    • Brain and Mind Centre, Camperdown (NSW) — Recruiting
    • Southern Neurology, Kogarah (NSW) — Recruiting
    • John Hunter Hospital, New Lambton Heights (NSW) — Recruiting
    • Box Hill Hospital, Box Hill (VIC) — Recruiting
    • Austin Health, Heidelberg (VIC) — Recruiting
    Who can join Age 18 Years to 60 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Hoffmann-La Roche
    Timeline
    Started 10 March 2026 Today 16 October 2026 Estimated completion 30 May 2028

    NCT07282574 · Checked 14 October 2026

  • Recruiting Phase 1

    Phase 1 study for people with Multiple Sclerosis

    Where
    • Concord Repatriation General Hospital, Sydney (NSW) — Recruiting
    • Corner Hawkesbury Road and Darcy Road, Westmead (NSW) — Recruiting
    Who can join Age 18 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Kite, A Gilead Company
    Timeline
    Started 10 April 2026 Today 16 October 2026 Estimated completion 1 June 2029

    NCT07304154 · Checked 11 October 2026

  • Recruiting Phase 2

    Phase 2 study for people with Multiple Sclerosis

    Where
    • CMAX Clinical Research, Adelaide (SA) — Recruiting
    Who can join Age 18 Years to 65 Years. Sex Anyone, regardless of sex. Healthy volunteers Accepted.
    Sponsor Progentos Therapeutics
    Timeline
    Started 1 October 2026 Today 16 October 2026 Estimated completion 1 December 2028

    NCT07826689 · Checked 11 October 2026

  • Not yet recruiting Not a phased study

    Study for people with Multiple Sclerosis

    Where

    No Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.

    • Royal Melbourne Hospital, Melbourne (VIC) — this site's status is not stated on the record
    Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor University of Melbourne
    Timeline
    Started 1 November 2026 Today 16 October 2026 Estimated completion 1 June 2027

    NCT07875309 · Checked 15 October 2026

voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice

Trials not shown here

Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.

Trials overseas

636 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.

These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.

About Multiple Sclerosis

The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.

What is multiple sclerosis? Multiple sclerosis (MS) is a disease that affects your brain and spinal cord, also called the central nervous system. MS damages myelin, the protective coating around your nerve cells. Myelin helps nerves send messages quickly. When it's damaged, messages between your brain and body slow down or get blocked. This leads to MS symptoms. What are the types of multiple sclerosis? Not everyone with MS has the same experience. MS is grouped into types based on how the disease changes over time. Types of MS include: - Relapsing-remitting MS. The most common type. People have flare-ups of new or worsening symptoms (relapses), followed by periods of recovery with few or no symptoms. - Secondary-progressive MS. Some people with relapse-remitting MS later develop this type. Symptoms slowly get worse over time, with fewer or no recovery periods. - Primary-progressive MS. Symptoms slowly worsen from the start, without clear relapses or periods of recovery. - Clinically isolated syndrome. A single episode of symptoms like MS that last at least 24 hours. It may be an early sign of MS, but not everyone develops MS afterward. - Radiologically isolated syndrome. Brain changes that look like MS show up on an MRI, but the person has no symptoms. Some people go on to develop MS symptoms, and some do not. What causes multiple sclerosis? No one knows the exact cause of MS. Many believe it is an autoimmune disease. This means your immune system mistakenly attacks healthy cells. In MS, the immune system attacks myelin. Several factors may work together to raise the risk of MS, including: - A previous infection with Epstein-Barr virus, which is the most common cause of mononucleosis (mono). - Environmental influences, such as smoking, little sun exposure, or low levels of vitamin D. - Genetic factors, such as certain genes. These are parts of DNA in your cells that are passed down from your parents. Having certain genes may increase your risk of MS, but not everyone with these genes gets the disease. - A family history of MS, meaning having a close relative who has been diagnosed with MS. - Your sex, since MS is two to three times more common in women than in men. - Your age, since MS most often begins between the ages of 20 and 40. What are the symptoms of multiple sclerosis? MS symptoms vary from person to person. Some people have mild symptoms, while others may have more serious problems. Symptoms depend on which nerves are affected. Common symptoms may include: - Blurry or double vision, or eye pain (often due to optic neuritis) - Trouble with bladder control - Muscle weakness - Muscle stiffness or spasms - Trouble with coordination, walking, or balance - Numbness, tingling, or a "pins and needles" feeling - Thinking or memory problems - Fatigue - Dizziness or vertigo - Mood changes How is multiple sclerosis diagnosed? There is no specific test for MS. Your health care provider may use several tools to make a diagnosis, including: - A review of your health history and symptoms - A physical exam and neurological exam, which checks your reflexes, strength, and senses - An MRI scan to look for damage in the brain and spinal cord - Blood tests to rule out other conditions - A lumbar puncture (spinal tap) to check fluid around your brain and spinal cord for signs of MS What are the treatments for multiple sclerosis? There is no cure for MS, but treatment can help manage symptoms and slow the disease. Treatments may include: - Disease-modifying medicines. These help slow MS and reduce relapses. They may be taken as pills, injections, or infusions. - Medicines for symptoms, such as muscle stiffness or pain. - Physical and occupational therapy help with movement, strength, and daily activities. Living with MS can affect how you feel emotionally. To help you cope with these changes, try to reduce stress, connect with supportive people, eat healthy foods, and stay as active as you comfortably can. NIH: National Institute of Neurological Disorders and Stroke

US source; availability in Australia may differ.

Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.

Sources and dates

  • ClinicalTrials.gov – trial records, statuses and site lists
  • ISRCTN registry – trial records for studies registered there
  • MedlinePlus – the About text above, reproduced exactly
  • ClinicalTrials.gov processing date: 15 October 2026.
  • This page last checked by Voxsanity: 15 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

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