Multiple Sclerosis Trial, Recruiting NCT05958381 Sponsor: The University of Texas at Dallas Condition: Multiple Sclerosis
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Multiple Sclerosis Trial, Recruiting

NCT05958381
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with relapsing-remitting multiple sclerosis (RRMS), a type of MS where symptoms come and go in episodes
  • People who have shown a specific type of memory difficulty (trouble retrieving memories) based on neuropsychological testing done at the research lab
  • People who can speak and read English fluently

Who may not be able to join:

  • People who have had an MS relapse, a sudden worsening of MS symptoms, or a course of steroid treatment within the two months before testing
  • People who take benzodiazepines (a type of sedative or anti-anxiety medication) unless they have been on a stable dose for at least two months
  • People who have certain other brain or neurological conditions, including dementia, epilepsy or seizure disorders, severe traumatic brain injury, a brain tumour, stroke, abnormal blood vessels in the brain, Parkinson's disease, or Huntington's disease
  • People who are currently misusing drugs or substances
  • People who are unable to give informed consent to participate
  • People who have metal implants in the skull or head area
  • People who have skull defects that would interfere with the brain stimulation technique used in this trial (confirm with trial site)
  • People who are taking certain medications that may interact with the brain stimulation used in this trial, including anti-seizure medications, L-dopa, carbamazepine, sulpiride, pergolide, lorazepam, rivastigmine, dextromethorphan, D-cycloserine, flunarizine, or ropinirole
  • People taking stimulant medications such as dextroamphetamine, amphetamine, modafinil, or armodafinil would need to stop taking them during the trial period (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: John Hart, Jr, MD, The University of Texas at Dallas

Phone: 972-833-3161

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
The University of Texas at Dallas
Registry
ClinicalTrials.gov
Start date
18 October 2023
Est. completion
29 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Treatment group differences in change from Baseline to 1-week Post-Treatment on Category Fluency; Treatment group differences in change from Baseline to 2-months Post-Treatment on Category Fluency; Treatment group differences in change from Baseline to 1-week Post-Treatment on COWAT; Treatment group differences in change from Baseline to 2-months Post-Treatment on COWAT

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov