Early Phase 1 Multiple Sclerosis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with multiple sclerosis (MS) — including primary progressive MS (PPMS), relapsing-remitting MS (RRMS), or secondary progressive MS (SPMS) — based on the 2017 McDonald diagnostic criteria
- Healthy volunteers of a similar age and sex to MS participants, as a comparison group
- People who are willing to undergo both PET and MRI brain scans as part of the study
- People who are willing and able to give their formal agreement to take part in the trial
Who may not be able to join:
- People who have another known neurological condition, a history of head injury, or a history of substance abuse
- People who have bipolar disorder or schizophrenia
- People who have other medical conditions that would make the study procedures unsafe (confirm with trial site)
- Women who are pregnant, breastfeeding, trying to become pregnant, or who suspect they may be pregnant
- People who experience claustrophobia (fear of enclosed spaces, which may affect the ability to undergo MRI or PET scanning)
- People who have implanted medical devices that are not safe to use with MRI machines
- People who have been treated with corticosteroids (a type of anti-inflammatory medication) within the past four weeks
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Tarun Singhal, MD, Brigham and Women's Hospital
Phone: 617-264-3043
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
PET measurements in individuals with PMS, RRMS, and healthy controls
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.