Phase 1 Multiple Sclerosis Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People who are between 18 and 70 years old at the time of signing the consent form.
- People who have been diagnosed with Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorders (NMOSD), Autoimmune Encephalitis (AiE), or Stiff Person Spectrum Disorder (SPSD) for at least 6 months, based on recognised diagnostic standards.
- People for whom standard treatments have not worked.
- People whose bone marrow, blood clotting, heart, lungs, liver, and kidneys are functioning at an adequate level.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who test positive for Hepatitis B, Hepatitis C, HIV, syphilis (Treponema Pallidum), Cytomegalovirus (CMV) DNA, or Epstein-Barr Virus (EBV) DNA.
- People who have an active infection that is not under control.
- People who received a live vaccine within 4 weeks before signing the consent form.
- People who have had a major organ transplant, or a bone marrow or blood stem cell transplant at any point in the past.
- People who have had a serious heart or cardiovascular condition in the 6 months before screening.
- People who have had significant bleeding (graded at level 2 or above) within 4 weeks before screening, or who require long-term blood-thinning medication (confirm with trial site).
- People who have not waited long enough after stopping a previous treatment before joining this trial (confirm with trial site).
- People who have previously been treated with CAR-T cell therapy or any genetically modified T cell therapy.
- People who are pregnant or currently breastfeeding.
- People who have severe diseases or structural changes affecting the central nervous system (confirm with trial site).
- People who have had a cancer diagnosis within the 5 years before signing the consent form.
- People for whom a lumbar puncture (spinal tap) is medically unsuitable.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +86 21 52888159
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Primary endpoints
Incidence and severity of Adverse Events [Safety and Tolerability]; The subsequent recommended dose of C-CAR168 in patients with central nervous system autoimmune diseases refractory to standard therapy
Can't join this trial?
Data last synced from ClinicalTrials.gov: 17 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.