Multiple Sclerosis Trial, Recruiting NCT06276634 Sponsor: Shirley Ryan AbilityLab Condition: Multiple Sclerosis
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Multiple Sclerosis Trial, Recruiting

NCT06276634
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a relapsing form of multiple sclerosis, including relapsing-remitting MS or secondary-progressive MS
  • People whose level of physical disability falls within a specific range, as measured by a standard MS disability scale called the EDSS (score between 3 and 6.5 — confirm with trial site for what this means for your situation)
  • People whose motor (movement-related) function scores fall within a specific range on a standard assessment scale (score between 2 and 4 — confirm with trial site)
  • People who have not had a relapse (a flare-up of MS symptoms) for at least one year
  • People aged 18 to 75 years old
  • People who are safe to have an MRI scan, based on answers to a standard MRI safety questionnaire
  • People who are taking the medication dalfampridine, provided the dose has stayed the same for at least two months before the screening visit

Who may not be able to join:

  • People whose baseline MRI scan shows active, inflamed MS lesions or signs of a recent stroke-like event in the brain
  • People with blood pressure that is outside a controlled range (confirm with trial site for specific values)
  • People with a history of epilepsy
  • People who have chronic obstructive pulmonary disease (a long-term lung condition)
  • People with sleep apnea that is not well controlled
  • People who are pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Milap Sandhu, Pt, PhD, Shirley Ryan AbilityLab

Phone: 3122381435

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Shirley Ryan AbilityLab
Registry
ClinicalTrials.gov
Start date
30 April 2024
Est. completion
3 November 2025

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Ankle Plantarflexion Strength

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov