Atrial Fibrillation

**Who might be able to join this trial:** - You have had at least 2 episodes of atrial fibrillation (an irregular heartbeat) in the past 6 months, each lasting at least 1 hour, with at least one confirmed by a heart tracing (ECG); OR one longer episode lasting 7 or more days confirmed by ECG; OR one continuous episode...

**Who might be able to join this trial:** - You are planning to have a catheter ablation procedure because you have episodes of atrial fibrillation (an irregular heartbeat) that causes symptoms, and at least one medication meant to control heart rhythm has not worked or you could not tolerate it - Your doctor has noted...

**Who might be able to join this trial:** - You are planning to have a catheter ablation procedure for atrial fibrillation (a heart rhythm problem) that causes symptoms - Your doctor has noted that your atrial fibrillation episodes come and go on their own - You have had at least one atrial fibrillation episode recorde...

**Who might be able to join this trial:** - People who had at least one episode of atrial fibrillation (an irregular heart rhythm) that occurred during or after a non-heart-related surgery or a serious illness requiring a hospital stay within the past 35 days - People whose heart is beating in a normal, regular rhythm...

Who might be able to join this trial: - People who were first diagnosed with atrial fibrillation (an irregular heart rhythm) within the last 5 years, with that diagnosis recorded on a heart tracing (ECG) taken from the surface of the skin - People who have a high number of health risk factors, measured by a scoring sys...

Who might be able to join this trial: - People who have been diagnosed with symptomatic paroxysmal atrial fibrillation (AF), meaning AF episodes that come and go and cause noticeable symptoms. - People who have had at least two symptomatic AF episodes in the last six months before joining the trial. - People who have h...

**Who might be able to join this trial:** - People aged 18 or older (or older if local laws require it) - People who have had exactly one previous catheter-based heart procedure (done from inside the heart) to treat atrial fibrillation (AF), which at minimum targeted the pulmonary veins (the vessels connecting the lun...

**Who might be able to join this trial:** - People who have had exactly one previous ablation procedure for atrial fibrillation (AF) in the past 3 years - People whose AF, or a related heart rhythm problem, came back at least 90 days after their first ablation, with a doctor's note confirming at least one symptomatic...

Who might be able to join this trial: - People between 18 and 80 years old - People who participate in endurance sports for at least 4 hours per week - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm condition) - People who already record their training activity using platforms such a...

Who might be able to join this trial: - People who are at least 18 years old, of any gender - People who have had or currently have a heart rhythm problem (cardiac arrhythmia), OR family members of people with a heart rhythm problem, OR people with no heart rhythm problem who would participate as a control (comparison)...

Who might be able to join this trial: - You are 18 years of age or older - You are in a state of shock (dangerously low blood pressure that has not improved with fluids) and need blood pressure-supporting medications given through a central line (a tube inserted into a large vein) Who may not be able to join: - Your h...

Who might be able to join this trial: - People who are scheduled to have a catheter ablation procedure for atrial fibrillation (an irregular heartbeat condition) because their symptoms have not improved with medication Who may not be able to join: - People who do not agree to take part in the study - People whose atri...

Who might be able to join this trial: - People who are 18 years of age or older Who may not be able to join: - People who are under 18 years of age - People who are not willing to sign an informed consent form (a document agreeing to take part in the trial) Important: Always verify eligibility with the trial site dir...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have a history of atrial fibrillation (an irregular heart rhythm) that comes and goes or is persistent, with symptoms occurring at least twice a month - People who have had a heart tracing (ECG) recorded within the past mo...

"Who might be able to join this trial: - Adults aged 18 years or older who are having a procedure to close off a small pouch in the heart (called the left atrial appendage), either through a blood vessel or through the outer surface of the heart Who may not be able to join: - There are no listed exclusion criteria for...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have non-valvular atrial fibrillation (an irregular heartbeat not caused by a heart valve problem) that is occasional, ongoing, or permanent, and has been confirmed by a heart tracing test (ECG) - People who are willing and able to s...

Who might be able to join this trial: - People who have had a dual-chamber permanent pacemaker or defibrillator (a device with two leads implanted in the heart) fitted within the last 10 years Who may not be able to join: - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm) confirmed b...

"Who might be able to join this trial: - People aged between 21 and 80 years old who have had a heart procedure to treat an irregular heartbeat condition called Atrial Fibrillation, where doctors used a technique called ablation (which uses energy to correct the abnormal electrical signals in the heart) Who may not be...

Who might be able to join this trial: - You have been diagnosed with atrial fibrillation (an irregular heartbeat condition) - You are being treated with a heart surgery procedure to correct the irregular heartbeat (known as surgical ablation) Who may not be able to join: - You do not wish to take part in the trial Im...

Who might be able to join this trial: - People who are 18 years of age or older - People who are scheduled to have a procedure called catheter ablation because they have an irregular heartbeat condition known as paroxysmal atrial fibrillation that is causing symptoms - People for whom at least one medication used to co...

**Who might be able to join this trial:** - People who are 18 years of age or older (there is no upper age limit for the general trial) - People who have a history of a type of irregular heartbeat called atrial fibrillation (paroxysmal, persistent, or long-standing), confirmed by a heart tracing (ECG) - People whose a...

Who might be able to join this trial: - You have been diagnosed with atrial fibrillation (an irregular heartbeat condition) and are being treated at the Emergency Department of the Medical University of Vienna - You have read and signed a consent form agreeing to take part in the trial Who may not be able to join: - Y...

**Who might be able to join this trial:** - People who have a type of irregular heartbeat called atrial fibrillation (AF) that is not the short, intermittent kind (known as "non-paroxysmal" AF) - People who have already tried at least one medication to control their heart rhythm, but it either did not work or caused s...

Who might be able to join this trial: - You have a pacemaker or a device called an implanted cardioverter defibrillator (ICD) that has a lead (wire) connected to the upper chamber of your heart - You have a score of 2 or more on a stroke risk assessment tool called the CHADS-VASc score (confirm with trial site) - Your...

Who might be able to join this trial: - People who are scheduled to have heart surgery, such as bypass surgery, valve surgery, or a minimally invasive valve replacement procedure (transcatheter valve implantation) Who may not be able to join: - People who are pregnant - People whose surgery or procedure is classified...

Who might be able to join this trial: - People who have persistent or permanent atrial fibrillation (an irregular heart rhythm that does not go away on its own) - People whose heart rate is controlled, with a resting heart rate of 100 beats per minute or lower - People who are able to complete an exercise test that pus...

Who might be able to join this trial: - You must be over 18 years old. - You must be willing and able to understand the study details and sign a consent form agreeing to take part. - You must be available to attend follow-up appointments after joining the study. - You must have been diagnosed with either coronary arter...

**Who might be able to join this trial:** - People who have recently had a successful procedure to close off a part of the heart called the left atrial appendage, using either an Amplatzer or WATCHMAN device, within the past 37 days before joining the study - People who have been taking two blood-thinning medications t...

**Who might be able to join this trial:** - People who have a persistent or long-standing persistent form of atrial fibrillation (an irregular heartbeat that does not come and go but stays ongoing) - People who already need non-emergency open-heart surgery for another reason, such as a heart bypass operation or heart v...

**Who might be able to join this trial:** - You started doing endurance sports (triathlon, cycling, distance running of 1500 metres or longer, or rowing) **before age 30**, compete at a regional, national, or international level, are between **45 and 70 years old**, and train more than 10 hours per week (if you cycle...

"Who might be able to join this trial: - People who are scheduled to have a catheter-based heart procedure to treat an irregular heart rhythm called atrial fibrillation, specifically a procedure known as pulmonary vein isolation (where small areas of heart tissue are treated to stop abnormal electrical signals) Who ma...

**Who might be able to join this trial:** **If you have Atrial Fibrillation (an irregular heartbeat condition):** - You have a history of atrial fibrillation (irregular heartbeat), including the type that comes and goes - You have recently had (within the last 14 days) a special heart ultrasound called a TEE to look a...

**Who might be able to join this trial:** - People aged 18 or older who are on long-term dialysis because their kidneys have failed - People who have a type of irregular heartbeat called atrial fibrillation (either occasional, ongoing, or permanent), confirmed by a heart tracing (ECG) or a monitoring device recording...

**Who might be able to join this trial:** - People scheduled for their first planned (non-emergency) open-heart surgery, such as coronary artery bypass grafting (heart bypass surgery), heart valve repair or replacement, a combination of bypass and valve surgery, or a type of aortic root repair that preserves the valve...

Who might be able to join this trial: - People who are at least 18 years old - People who have had a bleed inside the brain (including bleeding into the brain's fluid-filled spaces), confirmed by a CT or MRI scan - People who can be enrolled in the trial between 14 and 180 days after their brain bleed occurred - People...

Who might be able to join this trial: - People aged 22 or older. - People who have been diagnosed with atrial fibrillation (an irregular heartbeat), including any type — occasional, ongoing, or continuous. - People who have at least one of the following heart or health risk factors: high blood pressure; diabetes; a his...

**Who might be able to join this trial:** - You have atrial fibrillation (an irregular heartbeat) that has lasted continuously for more than 7 days or more than 12 months - You are between 18 and 80 years old - Your doctor has recommended that you have a procedure (called ablation) to treat your atrial fibrillation, ba...

**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition) - People who agree to participate and sign a consent form - People covered by the Ontario Health Insurance Plan (OHIP) **Who may not be able to join:**...

Who might be able to join this trial: - People who come to the emergency room with atrial fibrillation or atrial flutter that started less than 48 hours ago - People whose emergency room doctor is planning to treat the irregular heart rhythm acutely - People who the attending emergency room doctor considers to be in ge...

**Who might be able to join this trial:** - You are scheduled to have a radiofrequency procedure (a type of heart rhythm treatment) for atrial fibrillation (AF) within the next 6 months. - You are 18 years of age or older. - You are covered by a social security or health insurance scheme. - You have been fully informed...

**Who might be able to join this trial:** - People who are able and willing to give written consent to take part in the trial - People who have a confirmed diagnosis of atrial fibrillation (an irregular heart rhythm), of any type — including paroxysmal, persistent, long-standing persistent, or permanent - People with...

**Who might be able to join this trial:** - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition) and have a stroke risk score above 1 based on a standard medical scoring system called CHA2DS2-VASc (confirm with trial site) **Who may not be able to join:** - People who are unwillin...

**Who might be able to join this trial:** - People aged 18 or older - People who have recently had a successful procedure to open blocked heart arteries (called PCI, either as an emergency or planned procedure) - People who have been diagnosed with an irregular heart rhythm called atrial fibrillation or atrial flutter...

**Who might be able to join this trial:** - People aged 65 or older, OR people aged 50 or older who also meet at least one of these additional conditions: a specific heart protein level above 400 pg/mL on a blood test (NT-proBNP), an enlarged upper-left chamber of the heart detected on imaging, or silent brain damage...

**Who might be able to join this trial:** - People who are over 18 years old - People who were hospitalised for a heart attack (either a severe type called STEMI or a less severe type called NSTEMI) and developed a new irregular heart rhythm called atrial fibrillation (AF) for the first time during that hospital stay -...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who are scheduled for a second heart rhythm procedure (ablation) for paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes), after having had a previous procedure to isolate the pulmonary veins - People for wh...

**Who might be able to join this trial:** - People aged 18 or older, of any gender - People who are able to understand what the study involves, are willing to take part voluntarily, sign a consent form, and attend follow-up visits as required - People who have a medical need for a procedure to close off a part of the...

Who might be able to join this trial: - You may be eligible if a heart monitoring test (called a Holter recording) showed that you have at least 30 irregular heartbeats per hour coming from the upper chambers of your heart, or a run of at least 20 of these irregular beats in a row. Who may not be able to join: - Peopl...

Who might be able to join this trial: - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation, either in short episodes or as an ongoing condition - People whose atrial fibrillation has come back even after being treated with at least one heart rhythm medication - People who have...

Who might be able to join this trial: - Adults aged 18 or older - People with a type of irregular heartbeat called atrial fibrillation (AF) — whether it comes and goes, has lasted a long time, or is ongoing — that is not caused by a heart valve problem, and who have a stroke risk score of 2 or higher on a standard medi...

Who might be able to join this trial: - You are 18 years of age or older - You have been recently diagnosed with atrial fibrillation (an irregular heartbeat), confirmed by a heart tracing test (ECG), and your doctor has determined you need to start blood thinning medication Who may not be able to join: - Your kidneys...

**Who might be able to join this trial:** - Adults aged 18 or older who are scheduled to have a heart rhythm procedure (called ablation — using radiofrequency, pulsed field, or cryo-balloon methods) to treat atrial fibrillation (an irregular heartbeat), in line with current medical guidelines. - People whose atrial fi...

Who might be able to join this trial: - You must be 18 years old or older, either male or female. - You must have an irregular heart rhythm called atrial fibrillation (AF), which is not caused by a temporary or reversible condition (such as a recent heart attack, blood clot in the lungs, recent surgery, or thyroid prob...

**Who might be able to join this trial:** - Adults (18 years or older) - People who are either being treated as outpatients or are currently in hospital - People who have a confirmed active cancer diagnosis — meaning cancer diagnosed within the past 6 months, or cancer that has come back or spread and is currently bein...

**Who might be able to join this trial:** - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition) — whether in the past, currently, or as an ongoing condition - People who are aged between 55 and 73 years old at the time of joining the trial **Who may not be able to join:** - Peopl...

Who might be able to join this trial: - People who are over 18 years old and covered by a social security scheme. - People who have bleeding in the urine caused by bladder damage from radiation treatment, and who also have an irregular heart rhythm (called atrial fibrillation) that is not related to a heart valve probl...

Who might be able to join this trial: - People who have atrial fibrillation (an irregular heartbeat condition) and are between 18 and 79 years old, OR people between 40 and 79 years old who have been assessed as being at moderate or high risk for cardiovascular disease using a standard risk calculation tool called the...

**Who might be able to join this trial:** - People aged between 18 and 80 years old. - People who have persistent atrial fibrillation (an irregular heart rhythm that is ongoing or has required an electrical shock to reset the heart), confirmed by a heart tracing (ECG) or similar test within the past year. - People who...

Who might be able to join this trial: - People who have had their first ever episode of atrial fibrillation (an irregular heartbeat condition) - People who are under 35 years old - People whose atrial fibrillation was confirmed by a standard heart tracing test (ECG) or by a monitoring device that recorded the irregular...

Who might be able to join this trial: - People who have been identified as needing a left atrial appendage closure (a procedure to reduce stroke risk in people with an irregular heartbeat) based on French national medical guidelines. - People aged 18 or older. - People who have given written consent to take part in the...

**Who might be able to join this trial:** - You are between 18 and 75 years old. - You have been diagnosed with mild sleep apnea (breathing interruptions during sleep), confirmed by an overnight sleep study — and have **no** history of irregular heart rhythm (atrial fibrillation). - You have been diagnosed with modera...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form - People who have paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) with at least one episode in the past 12 months — though people already taking heart rhythm medicat...

**Who might be able to join this trial:** - You are 18 years old or older - You have been diagnosed with or are suspected to have a serious infection, and have been started on antibiotics - You need medication to keep your blood pressure stable (specifically norepinephrine or epinephrine) and have been on it for at le...

Who might be able to join this trial: - People who are 18 years of age or older - People who are currently admitted to hospital as an inpatient - People who have been diagnosed with at least one of three heart conditions: heart failure, coronary artery disease (a condition where the arteries supplying the heart become...

Who might be able to join this trial: - People who are scheduled for planned (non-emergency) open heart surgery - People who are older than 20 years of age Who may not be able to join: - People (or their legal decision-maker) who do not wish to participate in the trial - People who are already taking part in another c...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF) — either the kind that comes and goes (paroxysmal) or the kind that persists over time (persistent) - People who are already scheduled to...

**Who might be able to join this trial:** - People who have undergone cardiac (heart) surgery - People (or their next of kin) who have signed a consent form to take part - People who develop a new irregular heart rhythm called atrial fibrillation (a condition where the upper chambers of the heart beat irregularly) for...

**Who might be able to join this trial:** - Adults aged 18 or older who are taking a type of blood-thinning medication called a direct oral anticoagulant (DOAC) and are scheduled for a planned heart artery imaging procedure (coronary angiogram) or a procedure to open blocked heart arteries (such as a stent placement) -...

Who might be able to join this trial: - People whose left atrium (one of the heart's chambers) measures less than 55 mm in size - People whose irregular heart rhythm (atrial fibrillation) has come back even while taking heart rhythm medications, or who cannot tolerate those medications - People for whom a doctor has de...

"Who might be able to join this trial: - Adults who are scheduled to have a catheter ablation procedure to treat an irregular heartbeat condition called atrial fibrillation - People who are able to understand and agree to participate in the trial on their own behalf Who may not be able to join: - Children and young pe...

Who might be able to join this trial: - You have a permanent form of irregular heartbeat called atrial fibrillation. - You have been admitted to hospital at least once in the past 12 months because of heart failure. - Your heart's pumping strength is above 40% (as measured by a heart scan). - Your resting heart rate is...

"Who might be able to join this trial: - People who have atrial fibrillation (an irregular heartbeat condition) and are scheduled to have their first-ever catheter ablation procedure (a treatment that uses energy to correct abnormal heart rhythms) at Charité-Campus Benjamin Franklin hospital - People who are 18 years o...

Who might be able to join this trial: - People who are scheduled for a planned (non-emergency) heart valve replacement surgery using a biological (tissue-based) valve, with no other heart procedures being done at the same time - People who have a normal, regular heart rhythm and are not taking any heart rhythm medicati...

Who might be able to join this trial: - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition). - People whose atrial fibrillation diagnosis was made within the last year before joining the trial. Who may not be able to join: - People who have had atrial fibrillation for longer than...

**Who might be able to join this trial:** - People who have had atrial fibrillation (an irregular heartbeat) recorded on a heart tracing test lasting longer than 30 seconds, within the past 6 months. - People whose situation makes them suitable for a procedure to close off a small pouch in the heart called the left at...

**Who might be able to join this trial:** - You have been scheduled by your doctor to have, or have already had, a heart ablation procedure (a treatment that uses energy to correct abnormal heart rhythms) - You are willing to sign a consent form agreeing to take part in the study - You are 18 years of age or older, or...

**Who might be able to join this trial:** - You have been diagnosed with symptomatic paroxysmal (comes and goes) or persistent atrial fibrillation (irregular heartbeat), confirmed by a doctor's notes and at least two recorded episodes in the past 12 months. - You have tried at least one heart rhythm medication but it e...

**Who might be able to join this trial:** - Adults aged over 18 years - People who have persistent atrial fibrillation (an irregular heart rhythm lasting more than 7 days but less than 1 year) that is causing symptoms, and whose condition meets current guidelines for a specific heart procedure called pulmonary vein is...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have been diagnosed with persistent atrial fibrillation (an ongoing irregular heart rhythm condition) - People whose level of symptoms related to their atrial fibrillation is not yet fully known or measured **Who may not be able to...

Who might be able to join this trial: - People who have been diagnosed with symptomatic atrial fibrillation (an irregular heartbeat) that comes and goes or is persistent, with at least two recorded episodes in the past 12 months confirmed by heart tracing tests. - People for whom at least one heart rhythm medication ha...

Who might be able to join this trial: - Adults aged 18 or older who are male or not currently pregnant - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF), whether it comes and goes, has lasted a long time, or is permanent - People whose doctors have calculated their stro...

**Who might be able to join this trial:** - People who are scheduled to have a catheter ablation procedure for atrial fibrillation (AF), with a confirmed AF diagnosis within the past 12 months before enrolling. - People who have had one previous ablation procedure to isolate the pulmonary veins (using cryo, radiofreque...

**Who might be able to join this trial:** - You have been diagnosed with diabetes mellitus (DM) - You experience episodes of an irregular heartbeat that come and go (known as paroxysmal atrial fibrillation, or AF) **Who may not be able to join:** - You have Type 1 diabetes - You have symptoms of low blood pressure, or...

**Who might be able to join this trial:** - You have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) that is causing symptoms - You are 18 years of age or older (or meet the minimum age required in your country) - Your doctor is planning to treat your condition usi...

**Who might be able to join this trial:** - People who are older than 60 years of age - People who have been diagnosed with a type of stroke called ESUS (a stroke where no clear cause was found) within the last 180 days (about 6 months) from when the stroke started - People in whom a hole in the heart called a PFO (pat...

**Who might be able to join this trial:** - You have persistent atrial fibrillation (an irregular heartbeat that has continued without stopping for at least 7 days), confirmed by your cardiologist - Your atrial fibrillation causes symptoms and has not been controlled by at least one heart rhythm medication, including...

Who might be able to join this trial: - People who have been diagnosed with non-valvular atrial fibrillation (an irregular heartbeat not caused by a heart valve problem), including types that come and go or are ongoing - People between 18 and 80 years old - People whose left atrium (one of the heart's chambers) measure...

"Who might be able to join this trial: - Adults aged 18 or older. - People who show signs of a possible stroke, identified by standard stroke screening tools used by emergency teams. - People whose symptoms started within the last 24 hours. - People who are able to give informed consent to take part. - People who are n...

Who might be able to join this trial: - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition) - People who are able to make their own decisions, understand what the trial involves, and sign a consent form Who may not be able to join: - There are no stated exclusion criteria — the t...

**Who might be able to join this trial:** *ICM group (with implantable cardiac monitor):* - Adults aged 18 or older - Able and willing to provide written consent to participate - Diagnosed with a type 1 heart attack (as defined by current international medical guidelines) - Coronary arteries that are not significantly...

**Who might be able to join this trial:** - People who are older than 20 years of age. - People who have a stable, ongoing irregular heartbeat (called persistent atrial fibrillation) and have been taking a type of heart-rate-slowing medication called a beta-blocker, at the same dose, for at least 3 months. - People who...

**Who might be able to join this trial:** - People who are older than 20 years of age. - People who are currently taking a NOAC (a type of blood-thinning medication, also called a Non-Vitamin K Antagonist Oral Anticoagulant). **Who may not be able to join:** - People who are unable to provide at least one blood sample...

**Who might be able to join this trial:** - People who have had a successful procedure to open blocked heart arteries (called PCI) due to chest pain caused by reduced blood flow (unstable angina or stable coronary artery disease) - People who have a type of irregular heartbeat called atrial fibrillation that is not ca...

**Who might be able to join this trial:** - People who are scheduled for cardiac surgery at the Mayo Clinic in Rochester, Minnesota. - People who are scheduled to have mitral or aortic valve surgery, with or without also having coronary artery bypass grafting (a procedure to improve blood flow to the heart). **Who may...

**Who might be able to join this trial:** - People who have been referred for an ablation procedure or Maze surgery at Stanford Medicine for persistent atrial fibrillation (a type of irregular heartbeat that lasts more than 7 days or requires a medical procedure to stop) - People whose irregular heartbeat has not been...

**Who might be able to join this trial:** - You are 18 years of age or older and able to give your own consent to participate - You have a longer-than-normal delay in the electrical signal between the upper and lower chambers of your heart (a measurement called PR interval greater than 180 ms on a heart tracing) - You...

**Who might be able to join this trial:** - People aged 18 years or older - People who are able to read, understand, and sign a consent form agreeing to take part - People who have been diagnosed with atrial fibrillation (an irregular heartbeat), whether it is permanent, long-lasting, or comes and goes - People whose...

**Who might be able to join this trial:** - You are having an ablation procedure at Stanford for atrial fibrillation (AF) that either stops on its own within 7 days, or requires a medical procedure to stop it. - You have already tried at least one medication to control your heart rhythm that either did not work or caus...

**Who might be able to join this trial:** - People of Chinese background who have a type of irregular heartbeat (called non-valvular atrial fibrillation) and have been taking one of these blood-thinning medicines for 6 months or more: apixaban, dabigatran, edoxaban, or rivaroxaban. - People between 18 and 80 years old....

**Who might be able to join this trial:** - You have been diagnosed with atrial fibrillation (an irregular heartbeat), confirmed by a heart tracing (ECG), heart monitor, or implanted device, OR you have been diagnosed with a blood clot condition (either a new or returning clot in a vein) - You have been taking blood-th...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have a type of irregular heartbeat called atrial fibrillation (AF) that is either persistent (lasting a long time without stopping on its own) or long-standing persistent (lasting more than a year) - People whose left atrium (one of the he...

**Who might be able to join this trial:** - People who have been assessed as suitable candidates for a catheter ablation procedure for atrial fibrillation (AF), including those with a history of symptomatic persistent AF, or those having a repeat procedure for persistent or paroxysmal AF under certain conditions (conf...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation (either episodes that come and go, or a more ongoing form), meeting specific diagnosis guidelines set by a major European heart organisation in 2020 - Peop...

Who might be able to join this trial: - You are between 18 and 85 years old - You are able and willing to sign a consent form agreeing to take part in the study Who may not be able to join: - You do not have a good enough understanding of the German language to read the study documents and complete a computer-assisted...

Who might be able to join this trial: - People who have any type of heart or blood vessel condition. - People who are able to give their consent to take part in the study. - People who are proficient in English. - People who have access to a device (such as a smartphone or tablet) that can run a mobile app. - People wh...

Who might be able to join this trial: - Adults aged 18 years or older - People who own a smartphone (iPhone or Android) with an active phone number, and who are willing to download the Eureka Research Platform app - People who have an email address that can be used to access a web portal on any internet-connected devic...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have given written consent to participate - People with heart failure that causes symptoms, rated as moderate (a classification doctors use called NYHA Class II or III) - People who have a type of irregular heartbeat called atrial fibrill...

Who might be able to join this trial: - You have a condition called Beta-thalassemia that requires regular blood transfusions to manage - You are currently being monitored and receiving care at the Cardiology Unit of the University Hospital of Ferrara - You have had a heart rhythm test (ECG/electrocardiogram) performed...

**Who might be able to join this trial:** - You are between 18 and 85 years old (male or female) - You have been diagnosed with paroxysmal atrial fibrillation (an irregular heartbeat that comes and goes) and are experiencing symptoms from it - Your doctor has determined that a catheter ablation procedure (a treatment f...

Who might be able to join this trial: - You have atrial fibrillation (an irregular heartbeat) that is causing symptoms such as palpitations, shortness of breath, or fatigue - Your doctor has recommended a procedure called pulmonary vein isolation (a treatment to correct the irregular heartbeat) - You are able to unders...

Who might be able to join this trial: - Any patient who has been recommended by their doctor to have a device implanted to close a small pouch in the heart called the left atrial appendage, regardless of the reason for the recommendation or whether the procedure ends up being successful Who may not be able to join: -...

**Who might be able to join this trial:** - People aged 55 years or older - People who have been diagnosed with a stroke where the cause could not be found, after completing a standard set of tests including brain scans, blood vessel scans, a 24-hour heart rhythm test, and a heart ultrasound - People who have had a str...

**Who might be able to join this trial:** - Adults aged 18 or older - People who were admitted to Amiens University Hospital for heart surgery that involved being connected to a heart-lung bypass machine (known as "on-pump" cardiac surgery) - People whose on-pump heart surgery took place within the last 96 hours (4 da...

Who might be able to join this trial: - People who are 18 years of age or older, of any gender - People who have a documented history of atrial fibrillation (an irregular heartbeat condition) - People who are able to sign and provide written consent to participate Who may not be able to join: - People who have a moder...

**Who might be able to join this trial:** - People who have been assessed by their doctor as needing an ablation procedure for atrial fibrillation, in line with current medical guidelines. - People who are willing and able to give informed consent and attend all required appointments at an approved study centre. - Peop...

Who might be able to join this trial: - People who are scheduled to have a catheter ablation procedure (a heart procedure using thin, flexible tubes) for a type of irregular heartbeat called persistent atrial fibrillation, where the irregular heartbeat has been present for less than 24 months and no previous ablation p...

Who might be able to join this trial: - You must be older than 18 years of age. - You must have been diagnosed with atrial fibrillation (an irregular heartbeat), confirmed by a heart tracing test (ECG or Holter monitor). Who may not be able to join: - People who have blood diseases, autoimmune diseases, or cancer. - P...

**Who might be able to join this trial:** - People who are over 18 years of age - People who are willing to sign and date a consent form - People who are willing to have their heart monitored remotely - People who are about to start a type of cancer treatment called a BTK inhibitor for an approved condition (such as ce...

Who might be able to join this trial: - Adults (18 years or older) who are scheduled to have open heart surgery using standard surgical methods. - People who develop a new irregular heartbeat (called atrial fibrillation) after their heart surgery, which was not present before the operation. - People who agree to take p...

**Who might be able to join this trial:** - People who are able to understand the trial and have agreed in writing to take part - People who have been diagnosed with atrial fibrillation (an irregular heartbeat) or atrial flutter, confirmed by a heart tracing (ECG) or monitor recording - People aged 65–74 with a stroke...

**Who might be able to join this trial:** - People who are older than 18 years of age - People who have been diagnosed with paroxysmal atrial fibrillation (AF that comes and goes) or persistent atrial fibrillation (AF that lasts but has not been continuous for more than a year) - People whose AF quality-of-life score...

**Who might be able to join this trial:** - You have a confirmed diagnosis of atrial fibrillation (an irregular heartbeat condition) - You have had an ischemic stroke (a stroke caused by a blocked blood vessel, not bleeding) — including cases where stroke symptoms went away within 24 hours but a brain scan showed evid...

Who might be able to join this trial: - People who are currently receiving, or are planning to receive, a type of cancer medication called a BTK inhibitor or venetoclax - People who are 18 years of age or older, of any gender - People who are willing to follow all study procedures and are available for the full duratio...

Who might be able to join this trial: - People who have been newly diagnosed with atrial fibrillation (an irregular heart rhythm), whether it comes and goes, has lasted a while, or is ongoing - People who are 65 years of age or older - People who are willing and able to take part and attend scheduled follow-up appointm...

**Who might be able to join this trial:** - You have a heart device called a cardiac resynchronisation therapy (CRT) pacemaker or defibrillator, and have had it for more than 6 months - You have been diagnosed with an irregular heart rhythm called atrial fibrillation (AF), which is either permanent or keeps coming back...

Who might be able to join this trial: - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF) that comes and goes or is ongoing, and who have agreed to take part by signing a consent form - People who are currently taking blood-thinning medication (anticoagulants) in tablet o...

Who might be able to join this trial: - People aged between 60 and 80 years old - People who have been diagnosed with persistent atrial fibrillation (an irregular heart rhythm that doesn't stop on its own) - People whose doctor has recommended treatment to restore a normal heart rhythm - People who have scored between...

**Who might be able to join this trial:** - People aged 19 years or older who have ongoing, symptomatic atrial fibrillation (an irregular heart rhythm that hasn't stopped) and are scheduled for a catheter ablation procedure because medication has not controlled their condition - People who have a moderate amount of sc...

Who might be able to join this trial: - People who have atrial fibrillation (an irregular heartbeat), either the type that comes and goes (paroxysmal) or the type that has lasted a while but can still be treated (persistent) - People whose doctor has recommended a procedure to reset their heart rhythm, either using a c...

**Who might be able to join this trial:** - You are 55 years of age or older - You have recently been discharged from hospital after having an ischemic stroke (a stroke caused by a blood clot) where doctors were not able to find the exact cause - You are receiving follow-up care at the Emory Stroke Clinic - Your doctor...

Who might be able to join this trial: - People aged 18 or older - People who have been admitted to an intensive care unit (ICU) and are receiving breathing support through a mask or high-flow oxygen, or are on a breathing machine, where that support is expected to last more than 24 hours due to breathing difficulties -...

**Who might be able to join this trial:** - People aged 18 or older - People who have had heart surgery — including bypass surgery (CABG), heart valve surgery, replacement of the main artery leaving the heart (ascending aorta), or a combination of these — within the last 14 days - People who developed a new irregular h...

**Who might be able to join this trial:** - Adults between 18 and 100 years of age (men or women) - People who have been confirmed by an ECG (heart tracing test) to have an irregular heart rhythm called atrial fibrillation (AF) and/or atrial flutter, and who are scheduled for a planned procedure called catheter ablati...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have been newly diagnosed with atrial fibrillation (an irregular heart rhythm) while in the intensive care unit (ICU), confirmed by a heart tracing test or a recorded episode lasting at least 30 seconds - People who are currently in...

**Who might be able to join this trial:** - People who are over 18 years of age - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm) confirmed by a heart tracing (ECG) before their cardioversion procedure - People whose heart was successfully returned to a normal rhythm during cardiover...

Who might be able to join this trial: - People who are between 50 and 70 years old - People with a Body Mass Index (BMI) between 18 and 28 (a measure of body weight relative to height) - People who are scheduled to have a planned (non-emergency) coronary artery bypass graft (CABG) heart surgery at the Yangzhou Institut...

Who might be able to join this trial: - People who have been diagnosed with atrial fibrillation (an irregular heartbeat) that is not caused by a heart valve problem, within the last 12 months, at any level of stroke risk. - People who are 18 years of age or older. - People who are either not currently taking blood-thin...

Who might be able to join this trial: - People who are older than 18 years of age - People who are scheduled for a planned (non-emergency) procedure to restore a normal heart rhythm, either as an outpatient or as a hospital inpatient, for a condition called atrial fibrillation (an irregular heartbeat) - People for whom...

**Who might be able to join this trial:** - People who have paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) that causes symptoms and has not improved with one or more heart rhythm medications. - People who are willing to have a catheter ablation procedure (a procedure to treat the irr...

Who might be able to join this trial: - You must be willing and able to give your consent to take part in the trial - You must be 18 years old or older - You have been diagnosed with atrial fibrillation (an irregular heartbeat) - You have been told you have moderate or severe disease affecting your heart's mitral valve...

**Who might be able to join this trial:** - You live in the Capital Region of Denmark - You are over 18 years old - You have been diagnosed with atrial fibrillation (AF) that comes and goes or is ongoing (not permanent) - You have had or are scheduled for a cardioversion procedure (a procedure to reset your heart rhyt...

**Who might be able to join this trial:** - People aged 18 or older - People who have atrial fibrillation or atrial flutter and whose doctor has determined they need to take a type of blood thinner called a direct-acting oral anticoagulant (DOAC) for at least 12 months - People who have had a successful procedure to op...

Who might be able to join this trial: - People who are older than 18 years of age. - People who have been newly diagnosed with one of the following heart or blood vessel conditions: a heart attack (including certain types classified as acute coronary syndrome), cardiac arrest, atrial fibrillation or atrial flutter (irr...

**Who might be able to join this trial:** - You have been diagnosed with atrial fibrillation (an irregular heartbeat) that comes and goes, or that is ongoing - You are already scheduled to have a catheter ablation procedure (a treatment for irregular heartbeat) that is approved by European heart guidelines - You are be...

**Who might be able to join this trial:** - Adults aged 18 or older - People who are scheduled for a repeat heart rhythm procedure (called AF ablation) for atrial fibrillation — either the type that comes and goes (paroxysmal) or the type that is more continuous (persistent) — where the main recurring abnormal rhythm...

**Who might be able to join this trial:** - People aged 50 to 79 years who are patients at the Mitral Valve Clinic/CVC and are scheduled for planned (non-emergency) heart surgery to repair the mitral valve, without a specific heart rhythm procedure called the Cox MAZE procedure - People having mitral valve repair who a...

**Who might be able to join this trial:** - You have a type of irregular heartbeat called paroxysmal atrial fibrillation (AF that comes and goes) and are scheduled to have a specific heart procedure called pulmonary vein isolation (a procedure to treat this irregular heartbeat) **Who may not be able to join:** - You a...

Who might be able to join this trial: - People who have had a small heart monitor (called an implantable loop recorder with remote monitoring) surgically placed under their skin to track heart rhythms. - People who have had a stroke within the last six months that doctors could not find a clear cause for, after a full...

Who might be able to join this trial: - People who meet the standard medical guidelines for receiving a commercially available Watchman device (a small implant used to reduce stroke risk in people with a certain type of irregular heartbeat) - People who are not currently enrolled in another active clinical trial Who m...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing consent - People who have a heart rhythm problem (affecting the upper or lower chambers of the heart) that has been recorded on a heart monitor test within the past 12 months, and for whom an ablation procedure i...

Who might be able to join this trial: - You are 18 years of age or older. - You have been diagnosed with a long-lasting or ongoing irregular heartbeat (called persistent or long-standing persistent atrial fibrillation), confirmed by your medical records or a heart tracing test (ECG). - Your doctor has calculated your s...

Who might be able to join this trial: - People who have persistent atrial fibrillation (an irregular heartbeat that does not stop on its own) - People whose atrial fibrillation has not responded to medication, or who are unable to tolerate the medication used to treat it Who may not be able to join: - People who have...

Who might be able to join this trial: - People who are 18 years of age or older (or meet the minimum age required by local rules) - People who are already scheduled to have a procedure using the Affera Platform, which is a commercially available medical device - People who are willing and able to follow the study requi...

Who might be able to join this trial: - People having their first pulmonary vein isolation (PVI) procedure, which is a treatment for an irregular heart rhythm condition - People diagnosed with paroxysmal atrial fibrillation, meaning their irregular heart rhythm comes and goes rather than being constant - People whose h...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who are admitted to Amiens University Hospital for a planned coronary artery bypass graft surgery (a scheduled heart bypass operation) using a heart-lung bypass machine - People whose heart ultrasound (echocardiogram) images ar...

**Who might be able to join this trial:** - People over 18 years of age who have severe narrowing of the heart's aortic valve (aortic stenosis) and have had a procedure called TAVI (a non-surgical way to replace the aortic valve) - People who developed a new or worsened electrical conduction problem in their heart, det...

Who might be able to join this trial: - People who are scheduled to have an ablation procedure for a heart rhythm condition known as supraventricular tachycardia (this includes atrial fibrillation, typical atrial flutter, AV nodal reentry tachycardia, or an accessory pathway condition) - People who are 18 years of age...

**Who might be able to join this trial:** - You have been diagnosed with heart failure based on European heart specialist guidelines - Your heart is pumping at least 40% of its normal capacity (your doctor can check this) - You have scored a certain level on a specialist heart failure assessment called the HFA-PEFF sc...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who are able and willing to give their consent to participate - People who are already scheduled for a planned medical procedure that involves inserting a needle into a vein (such as a heart procedure for atrial fibrillation),...

Who might be able to join this trial: - People who have had a cardiac implantable electronic device (a pacemaker or similar heart device) implanted - People who have been diagnosed with a blood clot in a vein or lung (venous thromboembolism) - People who have experienced a heart attack or severe chest pain caused by re...

Who might be able to join this trial: - People who are able to give their consent to participate in the study - People aged between 18 and 85 years old - People who have had an irregular heart rhythm (atrial fibrillation) that has lasted more than 7 days but less than 2 years in total, as recorded in their medical note...

**Who might be able to join this trial:** - You have a score of 2 or higher on a standard stroke risk calculator used for people with atrial fibrillation (called the CHA2DS2-VASc score) - You are not a good candidate for long-term blood thinning medication, or there is a good reason to look for a non-medication alterna...

**Who might be able to join this trial:** - You have been diagnosed with atrial fibrillation (an irregular heartbeat) that comes and goes or is persistent, with at least one episode confirmed by a heart monitor or ECG recording within the past 24 months. - You are between 18 and 80 years old. - You are willing and able...

Who might be able to join this trial: - People aged 70 years or older - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm), confirmed by a heart tracing test (ECG or Holter monitor) showing an episode lasting at least 30 seconds within the past year - People whose atrial fibrillation-re...

Who might be able to join this trial: - You are 18 years old or older - You are already enrolled in a related study called OCEANIC-AF - You are willing and able to read and understand the patient information sheet and sign a consent form - You agree to have blood samples taken as part of the study Who may not be able...

**Who might be able to join this trial:** - You have atrial fibrillation (an irregular heartbeat) that comes and goes or is ongoing, and it causes symptoms - Your doctor has calculated a stroke risk score (called CHA₂DS₂-VASc) of 2 or higher - You have been diagnosed with a type of heart failure where the heart pumps n...

**Who might be able to join this trial:** - You are having radiofrequency catheter ablation (a procedure to treat an irregular heartbeat) for the very first time - You have been diagnosed with atrial fibrillation (an irregular heart rhythm) confirmed by an ECG (a heart tracing test) **Who may not be able to join:** -...

Who might be able to join this trial: - People who are 18 years of age or older - People who have had at least one confirmed episode of a specific type of irregular heart rhythm called atrial flutter, recorded by a heart tracing (ECG or Holter monitor) in the 180 days before joining the trial — recordings from other ho...

Who might be able to join this trial: - People who are at least 22 years old at the time of signing the consent form - People who have been advised by their doctor to have a Holter monitor test (a test that records heart activity over time) - People who are able to wear a smartwatch-style device called the HeartWatch o...

**Who might be able to join this trial:** - People who are older than 18 years and younger than 80 years - People who have had persistent atrial fibrillation (an irregular heart rhythm) lasting more than 1 year - People whose left atrium (a chamber of the heart) measures less than 6cm in size - People who are able to s...

"Who might be able to join this trial: - People admitted to hospital with a sudden worsening of heart failure who also had at least one previous hospital admission for worsening heart failure in the three months before this current admission. - People admitted to hospital with a sudden worsening of heart failure who al...

**Who might be able to join this trial:** - People who have been recently diagnosed with persistent atrial fibrillation (an irregular heart rhythm that doesn't stop on its own) that is causing symptoms, diagnosed no more than 6 months before joining the trial - People aged 18 or older - People with a body mass index (B...

Who might be able to join this trial: - Adults aged 18 or older who have a medical reason to take blood-thinning medication called a VKA (vitamin K antagonist, such as warfarin) long-term, and who have already been taking it for more than 6 months. Who may not be able to join: - People who do not wish to take part in...

**Who might be able to join this trial:** - Adults aged 19 years or older at the time of screening - People whose atrial fibrillation (an irregular heart rhythm) has been confirmed by a heart tracing (ECG) during screening and at the baseline visit - People who have a stroke risk score (called CHA2DS2-VASc) of 1 or mo...

Who might be able to join this trial: - People who have had one previous pulmonary vein isolation (a specific heart procedure for atrial fibrillation) using one of three methods: cryoballoon, radiofrequency ablation, or pulsed field ablation - People whose first pulmonary vein isolation procedure took place less than 5...

Who might be able to join this trial: - People who have persistent atrial fibrillation (an irregular heart rhythm that does not stop on its own) along with heart failure symptoms that have not improved enough with medication, and who have been assessed as suitable for a heart procedure called AF ablation, with no more...

Who might be able to join this trial: - People aged 18 years or older - People who have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes on its own) - People whose heart is pumping at a normal or near-normal level (a heart pumping function measurement of 50% or above...

Who might be able to join this trial: - People who are scheduled to have a catheter ablation procedure for atrial fibrillation (an irregular heartbeat) because medication has not worked well enough to control it. - People with a stroke risk score (called CHA2DS2-VASc, not counting gender) of between 1 and 4. - People w...

Who might be able to join this trial: - People who are scheduled to have their first-ever catheter ablation procedure for atrial fibrillation (an irregular heart rhythm condition) Who may not be able to join: - People under 18 years of age - People with a long-standing persistent form of atrial fibrillation (where the...

Who might be able to join this trial: - You are currently admitted to a hospital with a heart rhythm condition called atrial fibrillation or atrial flutter that is not caused by a heart valve problem Who may not be able to join: - You do not have atrial fibrillation or atrial flutter that is unrelated to a heart valve...

**Who might be able to join this trial:** - You have atrial fibrillation (an irregular heartbeat) that causes noticeable symptoms affecting your daily life - Your atrial fibrillation comes and goes, or has been ongoing, and medications to control your heart rate have not been enough - You want to have a procedure call...

Who might be able to join this trial: - People who are older than 18 years of age - People who have persistent atrial fibrillation (an irregular heart rhythm that has lasted more than 7 days) - People whose heart condition and health history place them at a moderate-to-high risk of stroke, as measured by a standard med...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have atrial fibrillation (an irregular heart rhythm) that has not responded to medication designed to control heart rhythm - People who have a persistent or long-standing persistent form of atrial fibrillation (meaning the...

Who might be able to join this trial: - People who have been diagnosed with atrial fibrillation (an irregular heartbeat) — either the kind that comes and goes (paroxysmal) or the kind that lasts longer (persistent) — confirmed by a heart tracing test (ECG) - People who experience noticeable symptoms from their atrial f...

Who might be able to join this trial: - People aged 18 to 85 who are scheduled to have surgery to remove part or all of the oesophagus (food pipe), or part or all of a lung. Who may not be able to join: - People for whom regional anaesthesia (numbing a specific area of the body with nerve-blocking injections) is not m...

**Who might be able to join this trial:** - You must be willing and able to sign a consent form before the study begins - You must be 18 years old or older - You must be scheduled for planned (non-emergency) heart surgery using a heart-lung bypass machine, and your surgery must be one of the following types: heart valv...

**Who might be able to join this trial:** - People who have permanent or persistent atrial fibrillation (an irregular heart rhythm that does not go back to normal on its own) - People who have moderate to severe heart failure symptoms (classified as NYHA Class II to IVa, meaning symptoms range from slight limitations...

**Who might be able to join this trial:** - You are 50 years of age or older - You are mostly independent in daily life with little to no disability (confirm with trial site) - You have recently (within the last 2 weeks) had a mini-stroke (TIA) AND either have a high risk score, an irregular heart rhythm called atrial...

Who might be able to join this trial: - People who have atrial fibrillation (an irregular heartbeat) that comes and goes on its own within 7 days, has not responded to medication, and whose doctor considers them a suitable candidate for an ablation procedure - People aged 18 years or older - People who are able and wil...

**Who might be able to join this trial:** - People who have a medical need for cardiac stimulation (a device to help regulate or support the heart's rhythm) - People who have already had a cardiac stimulation device implanted **Who may not be able to join:** - People under 18 years of age - People who are currently pr...

**Who might be able to join this trial:** - People between 18 and 85 years of age - People who are willing and able to give informed consent and attend all required follow-up visits - People who have a confirmed diagnosis of atrial fibrillation (an irregular heart rhythm) within the past year, supported by a heart tra...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have a confirmed diagnosis (shown in their medical records) of one of the following heart conditions: - **Atrial fibrillation** (any type — paroxysmal, persistent, long-standing persistent, or permanent), confirmed by an ECG recording l...

Who might be able to join this trial: - You are between 18 and 85 years old - You have persistent atrial fibrillation (an irregular heartbeat lasting at least 1 week) that is causing symptoms, is not caused by a heart valve problem, and has not been controlled by at least one heart rhythm medication - You are planning...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who are able to give informed consent (agree to participate after being told what the study involves) - People whose main diagnosis is a fast, irregular heartbeat called atrial fibrillation or atrial flutter, with a heart rate of 120 bea...

Who might be able to join this trial: - People who have persistent atrial fibrillation (an irregular heart rhythm lasting 7 days or more) that is still causing symptoms after already having a procedure called pulmonary vein isolation (PVI) to treat it Who may not be able to join: - People whose atrial fibrillation has...

Who might be able to join this trial: - People who are able to sign and date a consent form agreeing to take part in the study - People who are willing to follow all study procedures and are available for the full duration of the study - People who are 18 years of age or older, of any gender - People who have been diag...

Who might be able to join this trial: - People who are 18 years of age or older, or meet the minimum age required by local regulations. - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition). - People whose doctor is planning to perform a procedure using a specific commercially ava...

Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with atrial fibrillation (an irregular heartbeat), confirmed by a heart tracing test (ECG), either in a clinic or through a wearable heart monitor. Who may not be able to join: - People who have had a stroke caused by a blood clot...

Who might be able to join this trial: - People who have been diagnosed with persistent atrial fibrillation (a type of irregular heartbeat that does not stop on its own) - People who are over 18 years of age Who may not be able to join: - People who have an autoimmune disease (where the immune system mistakenly attacks...

Who might be able to join this trial: - People who are older than 18 years of age - People who have previously had some type of heart surgery that included a procedure to close off a small pouch in the heart called the left atrial appendage (this includes several different surgical techniques or devices, such as the At...

**Who might be able to join this trial:** - You have been diagnosed with persistent atrial fibrillation (an ongoing irregular heartbeat) and your doctor has recommended a procedure called catheter ablation to treat it. - Your doctor has assessed you as a suitable candidate for catheter ablation. - You are willing and a...

Who might be able to join this trial: - People who are 18 years of age or older - People who are able and willing to attend all study visits and check-ins for the full duration of the study - People who a doctor (the study investigator) has determined are medically appropriate to receive a left atrial appendage closure...

Who might be able to join this trial: - People aged 18 to 90 years old - People who have been diagnosed with persistent or permanent atrial fibrillation (an irregular heart rhythm that doesn't go away on its own) - People who received a CRT device (a type of heart pacemaker) or a specialised pacing device between 3 mon...

Who might be able to join this trial: - People aged 18 years or older - People with a type of irregular heartbeat called atrial fibrillation (not caused by a heart valve problem) who are already scheduled to have two specific heart procedures: a procedure to correct the irregular heartbeat (ablation) and a procedure to...

**Who might be able to join this trial:** - You need to be recommended for a specific heart procedure (called a left atrial exclusion) using a device called LAMBRE, as advised by French health authorities - You must be 18 years old or older - You must have been told about the study and agreed to take part **Who may no...

Who might be able to join this trial: - Adults aged 18 or older. - People who have given their informed consent to participate in the trial. Who may not be able to join: - People who are not able to make their own decisions or give consent (confirm with trial site). - People who are in generally poor health at the tim...

**Who might be able to join this trial:** - People aged between 18 and 75 years old - People with a body mass index (BMI) of 30 or higher (a measure of body weight relative to height) - People who have a type of irregular heartbeat called atrial fibrillation (AF) — either the kind that comes and goes (paroxysmal) or t...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing consent - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm) that either comes and goes in episodes lasting less than 7 days, or has been ongoing for 7 days or longer - People with a B...

**Who might be able to join this trial:** - Adults aged 18 or older (or older if required by local laws in the country where the trial is taking place) - People who have been diagnosed with symptomatic atrial fibrillation (an irregular heart rhythm) that is either persistent (ongoing) or paroxysmal (comes and goes), c...

Who might be able to join this trial: - People who have atrial fibrillation (an irregular heart rhythm) that has lasted continuously for between 1 and 3 years - People whose atrial fibrillation causes symptoms and has not responded to at least one medication designed to control heart rhythm - People between 18 and 75 y...

Who might be able to join this trial: - People who have been diagnosed with persistent atrial fibrillation (an irregular heart rhythm that continues for a long period) within the past 6 months - People whose left atrial diameter (a measurement of one of the heart's chambers) was between 40mm and 50mm before entering th...

**Who might be able to join this trial:** - Adults between the ages of 19 and under 85 - People who are willing to give their consent to take part and are able to attend follow-up appointments during the study - People who have both atrial fibrillation (an irregular heartbeat) and heart failure, and who have either had...

**Who might be able to join this trial:** - You have been diagnosed with persistent or long-standing persistent atrial fibrillation (an irregular heart rhythm that doesn't stop on its own) — (confirm with trial site which phase applies to you) - You have persistent atrial fibrillation and have never had a catheter abl...

**Who might be able to join this trial:** - You have been diagnosed with both atrial fibrillation (an irregular heartbeat) and moderate to severe obstructive sleep apnea (a condition where breathing repeatedly stops during sleep) - You are 18 years old or older - You are willing to take part in the study and agree to...

Who might be able to join this trial: - People who are older than 18 years of age - People who have had an acute (sudden-onset) stroke caused by a blood clot, with the stroke occurring within the last 14 days - People who have been diagnosed with a type of irregular heart rhythm called atrial fibrillation (AF) that is...

Who might be able to join this trial: - Adults aged 18 or older who are willing to take part and are able to sign a consent form - People who have been diagnosed with atrial fibrillation (an irregular heartbeat) and whose doctor has recommended a procedure called catheter ablation to treat it Who may not be able to jo...

Who might be able to join this trial: - Adults aged 18 years or older. - People who have been diagnosed with persistent atrial fibrillation (an ongoing irregular heartbeat). - People who have an elective cardioversion (a planned procedure to restore a normal heart rhythm) scheduled at the University of Ottawa Heart Ins...

Who might be able to join this trial: - You have atrial fibrillation (an irregular heartbeat) that is **not** caused by a heart valve problem, and your heart has been successfully returned to a normal rhythm — whether by medication, an electric shock treatment, or on its own. Who may not be able to join: - You have rh...

**Who might be able to join this trial:** - People who have given written agreement to take part in the study. - People aged 18 or older. - People who have been assessed as needing mitral valve surgery (either repair or replacement), with or without a procedure to close a small pouch in the heart called the left atria...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) and whose doctor has recommended a procedure called catheter ablation, according to specific medical guidelines - People who have h...

**Who might be able to join this trial:** - You have been diagnosed with heart failure where the heart pumps less effectively than normal (called "reduced ejection fraction"), and your heart's pumping strength has been measured at below 50% at some point in the last 12 months - You have been diagnosed with an irregula...

**Who might be able to join this trial:** - People aged between 18 and 80 years - People with symptomatic, persistent atrial fibrillation (an irregular heartbeat lasting more than 7 days without returning to normal on its own) that has been present for at least 6 months, with at least two episodes in the past 6 months...

**Who might be able to join this trial:** - People who have atrial fibrillation (an irregular heartbeat condition) or atrial flutter (a related heart rhythm problem) and are already scheduled to have a procedure called a transoesophageal echocardiogram (a scan of the heart done through the throat) to check whether they...

Who might be able to join this trial: - Adults who have had an acute ischemic stroke (a stroke caused by a blood clot) affecting any part of the brain, whether or not the cause is known - People who have a type of irregular heart rhythm called paroxysmal atrial fibrillation (AF), meaning it comes and goes rather than b...

Who might be able to join this trial: - People aged 18 years or older - People who are scheduled for a planned (non-emergency) catheter ablation procedure for atrial fibrillation, using specific-sized access tubes (6 to 14 Fr inner diameter) inserted into one or two veins in the groin area, regardless of the type of en...

**Who might be able to join this trial:** - People who are 18 years of age or older (but not older than 85) - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition), whether it comes and goes, has lasted a while, or has been ongoing for a long time - People whose heart was successfu...

Who might be able to join this trial: - Adults aged 18 years or older. - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF) that is not caused by a problem with the heart's mitral valve or a mechanical heart valve. - People whose stroke risk score (called CHA₂DS₂-VASc) is...

**Who might be able to join this trial:** - People between 18 and 80 years of age - People who have been diagnosed with symptomatic paroxysmal atrial fibrillation (an irregular heartbeat that comes and goes) with a history of less than 5 years - People who have moderate to severe mitral regurgitation (a leaky heart val...

Who might be able to join this trial: - Adults aged 18 or older - People who have never previously had an ablation procedure for atrial fibrillation - People diagnosed with paroxysmal atrial fibrillation, meaning their irregular heart rhythm episodes last less than 48 hours - People with early atrial fibrillation, mean...

Who might be able to join this trial: - People who have paroxysmal atrial fibrillation (an irregular heartbeat that comes and goes), with symptoms, and where the episodes stop on their own or with treatment within 7 days of starting - People aged between 18 and 70 years old - People who are willing and able to give inf...

**Who might be able to join this trial:** - People aged 18 or older - People who have a type of irregular heart rhythm called atrial fibrillation (AF) that is not caused by heart valve problems and is not the short, occasional type — and who were first diagnosed with AF within the last 5 years - People whose irregular...

Who might be able to join this trial: - You are 18 years old or older - You have had an ischemic stroke (a stroke caused by a blocked blood vessel) - You either have no known history of an irregular heartbeat called atrial fibrillation (AF), or you have been previously diagnosed with an occasional/intermittent form of...

Who might be able to join this trial: - People whose doctor has determined they need both the FARAPULSE™ heart rhythm treatment system and the WATCHMAN device to close off a part of the heart called the left atrial appendage, based on standard medical care. - People who are willing and able to give their informed conse...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have a chronic subdural hematoma (a blood collection between the brain and its outer covering) on one or both sides of the head that is causing symptoms, and where scans show it is mostly dark or grey in appearance — requiring a specific...

Who might be able to join this trial: - People aged 18 to 75 years old at the time of joining the trial - People who are willing and able to give informed consent and attend all required visits, tests, and follow-up appointments - People diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that...

Who might be able to join this trial: - People who are over 18 years old. - People who have been diagnosed with a type of irregular heart rhythm called atrial fibrillation (either the "comes and goes" type or the ongoing type) within the last 2 years. - People whose doctor has recommended a specific heart procedure tha...

**Who might be able to join this trial:** - People who have been diagnosed with permanent atrial fibrillation (an irregular heart rhythm that does not return to normal) - People aged 65 years or older - People whose atrial fibrillation has not responded to medications meant to control heart rhythm or heart rate, or who...

**Who might be able to join this trial:** - You are scheduled for planned (non-emergency) heart surgery through a full chest opening (sternotomy) - Your surgery is for one or more of the following conditions: blocked heart arteries, aortic valve problems, mitral valve problems, tricuspid valve problems, or disease of t...

Who might be able to join this trial: - Adults aged 18 years or older - People who need surgery on the upper part of the main blood vessel leaving the heart (the aorta), the heart valves, and/or the arteries that supply blood to the heart - People who are able to give their written agreement to take part in the study...

**Who might be able to join this trial:** - People between 20 and 85 years old. - People who are able to give written consent on their own free will and are willing to follow the study procedures. - People who are already scheduled to have open-chest heart surgery through a full cut down the centre of the chest (called...

**Who might be able to join this trial:** - People who are 18 years of age or older, of any gender or ethnic background - People who have given their free, informed, and written agreement to take part - People who are covered by, or benefit from, a social security scheme **Who may not be able to join:** - People under...

Who might be able to join this trial: - People who have been diagnosed with symptomatic persistent atrial fibrillation (an irregular heart rhythm lasting longer than 7 days but less than 12 months), confirmed by a doctor's notes and a heart tracing (ECG). - People who have been assessed as a suitable candidate for a ca...

**Who might be able to join this trial:** - People who have been diagnosed with at least one of the following conditions: heart failure, irregular heart rhythms, chronic kidney disease, coronary artery disease, a previous stroke or mini-stroke (TIA), or diabetes. - People who visit a primary care provider for any reaso...

**Who might be able to join this trial:** - People who are comfortable reading and writing in English - People who own a smartphone and are willing and able to use a specific mobile app called Eureka - People who have been diagnosed with a type of irregular heartbeat called paroxysmal atrial fibrillation (AFib), where...

**Who might be able to join this trial:** - People whose doctor has decided they should be treated with the FARAPULSE™ Pulsed Field Ablation system for heart tissue ablation, in line with the hospital's standard care practices - People who are willing and able to give their informed consent to take part - People who ar...

Who might be able to join this trial: - People who are scheduled to have coronary artery bypass graft (heart bypass) surgery Who may not be able to join: - People who are unable to sign a consent form agreeing to take part in the study - People with significant kidney problems, where the kidneys are working at a reduc...

Who might be able to join this trial: - Adults between 18 and 80 years old (or over 18 if local rules require it). - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm) that keeps coming back and has not been controlled by medication — either episodes that last less than 7 days (paroxysm...

Who might be able to join this trial: - People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition) - People who are planned to have a procedure called radiofrequency ablation carried out under general anesthesia (fully asleep) - People who are 18 years of age or older Who may not be abl...

Who might be able to join this trial: - People who are scheduled for a planned (non-emergency) heart bypass surgery that uses a heart-lung bypass machine. - People who are willing to sign a consent form agreeing to take part in the study. Who may not be able to join: - People whose heart's main pumping chamber is sign...

Who might be able to join this trial: - People aged 18 or older - People scheduled for a non-urgent heart operation, where at least 24 hours pass between the decision to operate and the actual surgery — specifically procedures involving coronary artery bypass grafting, aortic valve replacement, aortic surgery (without...

Who might be able to join this trial: - You have atrial fibrillation (an irregular heartbeat) that is not the "paroxysmal" type, meaning it does not come and go in short episodes but is more persistent or permanent - Your doctor has recommended a procedure called catheter ablation to treat your atrial fibrillation, in...

Who might be able to join this trial: - People who are having heart surgery performed by a specific surgeon (identified as V.K. in the trial) - People who have given their informed consent to take part in the trial Who may not be able to join: - People who have a history of an irregular heart rhythm condition called a...

Who might be able to join this trial: - You must have previously taken part in the "Tailored AF" study - You must have stayed in the Tailored AF study for the full 12-month follow-up period after your procedure without withdrawing - You must be willing and able to sign a consent form agreeing to take part in this exten...

**Who might be able to join this trial:** - You have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) that keeps coming back and is causing symptoms, with at least one recorded episode. - You have tried at least one medication to control your heart rhythm, but it ei...

Who might be able to join this trial: - People aged 18 years or older - People who have had a catheter ablation procedure as treatment for atrial fibrillation (an irregular heart rhythm) at least one year before joining the trial Who may not be able to join: - People who do not sign the consent form agreeing to take p...

**Who might be able to join this trial:** - You have been diagnosed with permanent atrial fibrillation (an irregular heart rhythm) lasting more than 6 months - Your heart's pumping strength is at or above a normal level (at least 50%) - You have been hospitalised at least once for heart failure in the past year - Your...

Who might be able to join this trial: - People aged 60 years or older - People who have never been diagnosed with atrial fibrillation (an irregular heartbeat condition) - People who are willing to be randomly assigned to a study group and attend follow-up appointments Who may not be able to join: - People who have a p...

**Who might be able to join this trial:** - Adults aged 18 or older who have atrial fibrillation or atrial flutter (in any form — ongoing, long-lasting, or coming and going) that requires blood-thinning medication - People currently taking warfarin (with a target INR of 2.0–3.0) or one of the following blood thinners a...

Who might be able to join this trial: - People who are either admitted to a hospital or attending as an outpatient. - People who have had at least one electrocardiogram (a heart tracing test, often called an ECG) within the past year. Who may not be able to join: - People who have been diagnosed with atrial fibrillati...

Who might be able to join this trial: - People who have a medical need for both a pulmonary vein isolation procedure (a heart rhythm treatment for atrial fibrillation) and a left atrial appendage closure procedure (a procedure to reduce stroke risk by closing off a small pouch in the heart) Who may not be able to join...

Who might be able to join this trial: - Adults between 18 and 80 years of age - People who had a heart rhythm procedure (ablation for atrial fibrillation or atrial flutter) roughly 2 to 12 months ago (within a specific time window around that range) - People with a heart stroke-risk score called CHA2DS2-VA of 2 or high...

Who might be able to join this trial: - Adults who are having a specific heart procedure called pulse field ablation to treat an irregular heart rhythm (atrial fibrillation and/or atrial flutter) as part of their normal medical care. - People for whom a bladder catheter (a thin tube inserted into the bladder to drain u...

**Who might be able to join this trial:** - People aged 18 to 80 years old - People who have been diagnosed with persistent atrial fibrillation (an ongoing irregular heart rhythm), confirmed by a heart tracing (ECG) - People who have moderate-to-severe or worse leaking of the mitral heart valve (specifically a type li...

**Who might be able to join this trial:** - You are 19 years old or older and have been diagnosed with atrial fibrillation (an irregular heartbeat condition) - You have at least one of the following health conditions: heart failure, high blood pressure, coronary artery disease (blocked arteries in the heart), periphera...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of joining the trial - People who have had a confirmed bleed in the brain (shown by a brain scan such as a CT or MRI) within 48 hours of symptoms starting - People who are able to give consent themselves, or who have a legal...

**Who might be able to join this trial:** - People who have been diagnosed with persistent (but not long-standing) atrial fibrillation (an irregular heart rhythm), or recurring atrial fibrillation, as defined by this study's criteria. - People who have recent heart electrical activity recordings (ECGs) from their atri...

**Who might be able to join this trial:** - People who are 40 years of age or older - People who have paroxysmal atrial fibrillation (AF), meaning a type of irregular heartbeat that comes and goes - People who have a recorded episode of AF (shown on a heart tracing or equivalent test) within the past 12 months — if som...

**Who might be able to join this trial:** - You have been recently diagnosed with a type of irregular heartbeat called atrial fibrillation that is not caused by a heart valve problem. - You have never taken blood-thinning tablets (anticoagulants) before joining the trial. - You are 18 years old or older. - You are will...

Who might be able to join this trial: - Adults aged 18 years or older - People whose main reason for seeking care is symptoms caused by atrial fibrillation (an irregular heartbeat condition) - People whose heart is beating faster than 100 beats per minute due to atrial fibrillation, as shown on a heart tracing test (EC...

Who might be able to join this trial: - People who are Veterans, male or female, aged 22 years or older - People who have been diagnosed with atrial fibrillation (an irregular heartbeat) or atrial flutter (a related heart rhythm condition) and are currently taking either apixaban or rivaroxaban (blood thinners) - Peopl...

Who might be able to join this trial: - Adults aged 18 or older who have atrial fibrillation, atrial flutter, or a blood clot condition (such as a clot in the leg or lungs), and who are taking a full-strength dose of one of these blood thinners: apixaban, dabigatran, edoxaban, or rivaroxaban (at specific doses suited t...

Who might be able to join this trial: - You are 18 years of age or older - You are having heart valve surgery or a coronary artery bypass grafting (CABG) procedure, which is a surgery to improve blood flow to the heart Who may not be able to join: - You are having surgery on the aorta (the main large artery coming fro...

**Who might be able to join this trial:** - People aged between 18 and 85 years old - People who are willing and able to give informed consent and attend all required follow-up visits as set out in the study plan - People who have a documented history of atrial fibrillation (an irregular heart rhythm) — either the typ...

Who might be able to join this trial: - People who have agreed to take part by signing a consent form and are willing to be monitored during the study. - People who have atrial fibrillation (an irregular heart rhythm) that has not responded to, or could not be tolerated, at least one type of heart rhythm medication (Cl...

**Who might be able to join this trial:** - You have been diagnosed with atrial fibrillation (an irregular heartbeat) that comes and goes or is ongoing, and it causes symptoms that keep coming back - You have already tried at least one medication used to control heart rhythm (a type called Class I or III antiarrhythmic...

Who might be able to join this trial: - People who have had a stroke and where a team of heart and brain specialists has agreed that closing a small natural opening in the heart (called a patent foramen ovale, or PFO) is the right treatment, following current medical guidelines. - People who are older than 18 years of...

**Who might be able to join this trial:** - You are 18 years of age or older and have been diagnosed with atrial fibrillation that is not caused by a heart valve problem - Your doctor has determined that you are a suitable candidate for both a left atrial appendage closure procedure (using the WATCHMAN FLX device) and...

**Who might be able to join this trial:** - People who have persistent atrial fibrillation (an irregular heart rhythm that has continued without stopping for more than 7 days) and are experiencing symptoms from it - People who have tried heart rhythm medications but found them ineffective, had bad side effects, or do n...

**Who might be able to join this trial:** - People aged 18 years or older. - People who have had a recorded episode of atrial fibrillation (an irregular heart rhythm) lasting longer than 30 seconds, confirmed by a heart tracing device such as an ECG, a Holter monitor, an implanted heart monitor, or a wearable ECG devic...

Who might be able to join this trial: - People who have been diagnosed with heart failure for at least 90 days and are currently experiencing moderate symptoms (not the most mild, but not the most severe) - People who, in the past year, were admitted to hospital with worsening heart failure as the main reason for admis...

Who might be able to join this trial: - People who are already scheduled and medically approved for open-heart surgery that requires the use of a heart-lung bypass machine and opening of the sac surrounding the heart. - People who are 65 years of age or older and have a stroke risk score (called CHA2DS2-VASc) of 3 or h...

Who might be able to join this trial: - People who are 21 years of age or older - People who own a smartphone - People who are able to use the Eureka mobile app - People who have a history of atrial fibrillation (an irregular heart rhythm) that comes and goes or has been ongoing for a period of time - People who have d...

Who might be able to join this trial: - People who are 18 years of age or older - People who have atrial fibrillation (an irregular heartbeat) that causes symptoms and is not caused by a temporary or treatable condition such as an infection, a blood clot in the lungs, or an overactive thyroid - People whose doctors, fo...

**Who might be able to join this trial:** - People who have been diagnosed with recurring, drug-resistant paroxysmal atrial fibrillation (a type of irregular heartbeat that starts and stops on its own or with treatment within 7 days), with at least two episodes recorded by a doctor in the past 6 months - People aged 1...

Who might be able to join this trial: - People who are 18 years of age or older - People who are willing to participate and have signed a consent form - People who have a confirmed or suspected heart rhythm problem - People who are able to use a smartphone and a mobile app called Kardi Ai - People whose smartphone meet...

Who might be able to join this trial: - People who are already scheduled to have a heart rhythm procedure called pulmonary vein isolation (PVI) using a specific device called the FARAPULSE catheter ablation system - People who have been diagnosed with a type of irregular heartbeat called paroxysmal atrial fibrillation...

**Atrial Fibrillation (AF) Group** Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm), including types that come and go or that persist over time - People who are scheduled to have their first-ever cathet...

**Who might be able to join this trial:** - You have been diagnosed with severe aortic stenosis (a serious narrowing of a heart valve) that is causing symptoms, and your doctors have recommended a procedure called TAVI (a minimally invasive heart valve replacement) - You are able to understand and follow the study inst...

Who might be able to join this trial: - People who are willing and able to sign a written consent form agreeing to take part - People who are 18 years of age or older - People who have been diagnosed with persistent atrial fibrillation (a type of irregular heartbeat that does not stop on its own) - People who are alrea...

**Who might be able to join this trial:** - People of any sex who have high blood pressure and are older than 75 years of age - People with high blood pressure who are between 65 and 75 years old and also have at least one of the following conditions: - Obesity - Type 2 diabetes - Obstructive sleep apnea (breath...

Who might be able to join this trial: - People between 18 and 85 years of age - People who have been diagnosed with persistent atrial fibrillation (an irregular heart rhythm that has lasted less than one year, or that has needed a procedure to restore normal rhythm) - People whose condition meets the current Japanese m...

Who might be able to join this trial: - People who are 18 years of age or older - People who have come to hospital with atrial fibrillation (an irregular heartbeat condition) and are planning to have an ablation procedure (a treatment that uses energy to correct the abnormal heart rhythm) Who may not be able to join:...

Who might be able to join this trial: - You are 18 years of age or older - You have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) and experience symptoms such as palpitations, dizziness, fatigue, shortness of breath, or chest discomfort - This would be your first...

Who might be able to join this trial: - People aged between 18 and 80 years old. - People who have persistent atrial fibrillation (an irregular heart rhythm lasting more than 90 days) that causes symptoms such as palpitations, near-fainting, fainting, tiredness, or shortness of breath. - People whose atrial fibrillatio...

Who might be able to join this trial: - The person must have given their informed consent to take part in the trial - The person must be undergoing a heart procedure called ablation (a treatment that uses energy to correct irregular heart rhythms) using a specific technology called pulsed field ablation (PFA) Who may...

**Who might be able to join this trial:** - You are 18 years old or older - You have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF), either the kind that comes and goes or the kind that lasts longer - Your doctor has recommended a procedure to treat your heart's irregular rhythm, spec...

Who might be able to join this trial: - People who are 18 years of age or older - People who have never had an ablation procedure for their heart rhythm condition before - People whose atrial fibrillation (an irregular heartbeat) has lasted for episodes of at least 7 days but no longer than 3 years continuously, includ...

Who might be able to join this trial: - People who are 22 years of age or older - People who have a documented or current history of atrial fibrillation (an irregular heart rhythm condition), including any type — paroxysmal (comes and goes), persistent, or long-standing persistent - People who are scheduled to have pla...

**Who might be able to join this trial:** - People who have been diagnosed with atrial fibrillation (an irregular heartbeat) that is not caused by a faulty or mechanical heart valve - People whose stroke risk score (called CHA2DS2-VA) is 2 or higher, indicating a moderate to high risk of stroke - People who meet the m...

Who might be able to join this trial: - People aged between 18 and 80 years old who have persistent atrial fibrillation (an irregular heartbeat that doesn't stop on its own) along with an enlarged left chamber of the heart (measured at a specific size range) - People who are willing to have their heart rhythm reset (ca...

**Who might be able to join this trial:** - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm), confirmed by a heart tracing test, a portable heart monitor, or an implanted heart device - People whose doctor has determined that a procedure to correct the irregular heart rhythm (called a...

Who might be able to join this trial: - People who have had atrial fibrillation (AF) or an irregular heart rhythm called atypical atrial flutter return after a previous procedure to treat it (called pulmonary vein isolation, or PVI) - People whose heart condition makes them suitable for a repeat pulmonary vein isolatio...

Who might be able to join this trial: - People who are 60 years of age or older - People who live in the Qujiang District - People who have been diagnosed with a long-term heart or blood vessel condition, such as high blood pressure, coronary artery disease, heart failure, irregular heartbeat (atrial fibrillation), or...

**Who might be able to join this trial:** - People who have a type of irregular heart rhythm called atrial fibrillation (AF) — either one that comes and goes, or one that is ongoing — confirmed by a heart tracing test (ECG) or a monitoring device within the past 24 months, with the episode lasting at least 30 seconds....

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with paroxysmal atrial fibrillation (an irregular heartbeat that comes and goes) and have had at least one episode lasting 30 seconds or more, confirmed by a heart monitor test - People who are willing a...

Who might be able to join this trial: - People aged 16 years or older - People who have been admitted to a medical-surgical intensive care unit at a hospital taking part in the trial - People for whom a magnesium replacement treatment plan has been ordered by their medical team Who may not be able to join: - People wh...

"Who might be able to join this trial: - Adults of any gender between 18 and 99 years old - People who are scheduled to have heart surgery - People who are able to answer survey questions Who may not be able to join: - People who have a type of irregular heartbeat called persistent or permanent atrial fibrillation - P...

**Who might be able to join this trial:** - You have been diagnosed with a heart or blood vessel (cardiovascular) condition, are male or female, and are older than 22 years of age - You are willing and able to sign a consent form agreeing to take part in the study - You agree to follow the study's procedures and requir...

**Who might be able to join this trial:** - People who have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that starts and stops on its own) or persistent atrial fibrillation (an irregular heartbeat lasting more than 7 days but less than 1 year), confirmed by a doctor's note and hear...

**Who might be able to join this trial:** - People aged 18 or older (or older if local laws require it) - People who have persistent atrial fibrillation (an irregular heart rhythm lasting more than 7 days but no longer than 365 days) that causes symptoms and has not responded to medication, confirmed by medical record...

**Who might be able to join this trial:** - People who have an irregular heart rhythm called atrial fibrillation (AF) that has been confirmed on a heart tracing (ECG), and who are already scheduled to have a procedure called electrical cardioversion (a controlled electric shock to reset the heart's rhythm) between 7 an...

Who might be able to join this trial: - People who have already had a heart rhythm test (called an electrophysiological study) or an electric shock treatment to restore normal heart rhythm (called electrical cardioversion) at University Hospital Düsseldorf since 2015 (for the past records part of the study) - People wh...

Who might be able to join this trial: - People who are at least 18 years old at the time of giving consent - People who are scheduled to have a catheter ablation procedure to treat atrial flutter or atrial fibrillation (irregular heart rhythms), as recommended by their doctor and in line with current medical guidelines...

**Who might be able to join this trial:** - You are 18 years of age or older (male or female) - You have had at least 2 episodes of atrial fibrillation (AF) or atrial flutter, and at least one of those must have been atrial fibrillation specifically - At least one of those AF episodes happened within the last 12 month...

Who might be able to join this trial: - People who are 21 years of age or older - People who have had a specific implanted device (called an HGNS device) placed to treat obstructive sleep apnea, and who are followed up at UCSF Health - People who are willing to temporarily stop using their upper airway stimulation devi...

**Who might be able to join this trial:** - People who have been diagnosed with paroxysmal atrial fibrillation (an irregular heartbeat that comes and goes) and are experiencing symptoms from it, where their doctor considers them a suitable candidate for a catheter ablation procedure (a procedure to correct the irregul...

**Who might be able to join this trial:** - People who have been diagnosed with paroxysmal atrial fibrillation (an irregular heartbeat that comes and goes) and have experienced symptoms from it - People whose heart specialist has determined that a procedure to isolate the pulmonary veins (the main electrical pathways i...

**Who might be able to join this trial:** - You are 18 years of age or older - You have had your first-ever stroke caused by a blocked blood vessel in the brain (ischemic stroke) **Who may not be able to join:** - You have bleeding in the brain (intracranial haemorrhage) - Your stroke has led to bleeding complications...

**Who might be able to join this trial:** - You are scheduled to receive treatment with the WATCHMAN FLX™ Pro device, which is used to close off a small pouch in the heart. - You have a type of irregular heartbeat called atrial fibrillation that is not caused by a problem with your heart valve, and your doctor has reco...

Who might be able to join this trial: - People who are willing and able to sign a written consent form agreeing to take part. - People who are 18 years of age or older. - People who have been diagnosed with a type of irregular heart rhythm called atrial fibrillation (AF), confirmed by a heart tracing (ECG), where episo...

Who might be able to join this trial: - People aged between 18 and 70 years old - People who are scheduled to have their first ablation procedure for atrial fibrillation (a heart rhythm condition) - People whose heart failure symptoms are mild or absent, meaning day-to-day activities are not significantly limited (conf...

Who might be able to join this trial: - People who are at least 18 years old at the time of signing the consent form - People who are already scheduled to have a catheter ablation procedure to treat atrial flutter (AFL) or atrial fibrillation (AF), as recommended by their doctor following standard medical guidelines -...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with atrial fibrillation (an irregular heart rhythm), confirmed by a heart monitoring test such as a Holter monitor, rhythm strip, or ECG - People with moderate heart failure symptoms, classified as NYH...

Who might be able to join this trial: - People who are having their first-ever procedure to isolate the pulmonary veins (the veins connecting the lungs to the heart) as a treatment for atrial fibrillation (an irregular heartbeat condition). - People who are male or non-pregnant female, aged 21 years or older. - People...

**Who might be able to join this trial:** - Your left atrium (a chamber in your heart) is enlarged, based on measurements taken during a heart scan - The walls of your heart's main pumping chamber are thicker than normal (15mm or more) - A specific measurement from your heart ultrasound (called E/e') is above 14, whic...

**Who might be able to join this trial:** - Adults aged 18 or older who are male or not currently pregnant - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF) that is not caused by a damaged heart valve - People whose AF-related stroke risk score meets a certain threshol...

**Who might be able to join this trial:** - People diagnosed with recurrent symptomatic paroxysmal atrial fibrillation (AF that starts and stops on its own) or persistent atrial fibrillation (AF that continues unless treated), with documented proof of episodes within the past 12 months - People with persistent AF who...

**Who might be able to join this trial:** - You are between 18 and 80 years old - You have been diagnosed with a type of irregular heartbeat called paroxysmal atrial fibrillation, where episodes stop on their own and last less than 7 days - You are scheduled to have your first-ever procedure (called radiofrequency cath...

**Who might be able to join this trial:** - You are 18 years of age or older - You are scheduled to have a planned heart bypass surgery (where surgeons use blood vessels to reroute blood around blocked arteries in the heart) **Who may not be able to join:** - You have a history of an irregular heart rhythm condition c...

**Who might be able to join this trial:** - You are between 18 and 75 years old (either gender) - You have been diagnosed with persistent atrial fibrillation (an irregular heart rhythm lasting more than 7 days) that is causing symptoms - Your medical records show evidence of this ongoing irregular heart rhythm, either...

Who might be able to join this trial: - People who have been diagnosed with recurring paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes), where episodes last more than 30 seconds but stop on their own or with treatment within 7 days, with at least 2 symptomatic episodes recorded by a doc...

"Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with atrial fibrillation or a fast abnormal heart rhythm (called atrial tachycardia), and whose heart is either currently in a normal rhythm or can be confirmed to be in a normal rhythm at the time of the h...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have had a spontaneous brain bleed (not caused by injury) between 14 days and 12 months before joining the trial - People for whom brain scan images from their brain bleed are available for the trial team to review - People...

Who might be able to join this trial: - People who have persistent atrial fibrillation (an irregular heart rhythm that doesn't stop on its own) and have not previously had a catheter ablation procedure for it, and are now planned to have one - People whose left atrium (one of the heart's chambers) is enlarged, as measu...

**Who might be able to join this trial:** - You (or a legal representative on your behalf) are willing and able to give consent to take part, following the rules of the institution and location - You have already received a Micra AV2 device (a small, wireless pacemaker) or are planned to receive one as part of your nor...

Who might be able to join this trial: - People who are 30 years of age or older. - People who have been diagnosed with a stroke where the cause could not be determined (called Embolic Stroke of Undetermined Source), and who have already had, or are planned to have, a small heart-monitoring device implanted under the sk...

**Who might be able to join this trial:** - People whose doctor has determined they need treatment with both the FARAPULSE™ pulse field ablation system and a WATCHMAN FLX™ Pro or WATCHMAN FLX™ left atrial appendage closure device, based on their hospital's standard care guidelines. - People who are willing and able to...

Who might be able to join this trial: - People diagnosed with atrial fibrillation (an irregular heartbeat) that comes and goes, or that is ongoing - People aged 18 years or older - People who are already scheduled to have a specific heart procedure called CTI ablation (a procedure that uses heat or cold energy to corre...