Phase 4 Atrial Fibrillation Trial, Recruiting NCT03968393 Sponsor: Population Health Research Institute Condition: Atrial Fibrillation
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Phase 4 Atrial Fibrillation Trial, Recruiting

NCT03968393
Recruiting Phase 4 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who had at least one episode of atrial fibrillation (an irregular heart rhythm) that occurred during or after a non-heart-related surgery or a serious illness requiring a hospital stay within the past 35 days
  • People whose heart is beating in a normal, regular rhythm at the time they would enter the trial
  • People who meet certain age and health risk combinations — for example, those aged 55–64 with heart or blood vessel disease or other risk factors, those aged 65–74 with similar risk factors, or those aged 75 and older (confirm specific details with trial site)
  • People who are able and willing to give written consent to participate

Who may not be able to join:

  • People whose main reason for being admitted to hospital was a heart condition
  • People who have a history of long-term or ongoing atrial fibrillation diagnosed before their surgery
  • People who already need to take long-term blood-thinning (anticoagulant) medication
  • People who already need to take two different types of blood-thinning (antiplatelet) medications long-term at the same time
  • People for whom blood-thinning medication would be considered unsafe or unsuitable
  • People with severely reduced kidney function
  • People with severe liver disease (the most serious stage of liver scarring)
  • People who have had a stroke within the past 14 days
  • People who had heart surgery within the past 35 days
  • People who have a history of bleeding inside the skull, eye, or spine that was not caused by an injury
  • People with a condition that causes problems with blood clotting or abnormal bleeding
  • People who are unlikely to be able to attend follow-up visits or take the study medications as required
  • People whose life expectancy is less than one year due to another serious illness
  • Women who are pregnant, breastfeeding, or capable of becoming pregnant and not using effective contraception
  • People who have already taken part in this trial previously

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: David Conen, MD, MPH, Population Health Research Institute

Phone: 1-905-594-0560

Australian sites

Canberra Hospital, Garran, Australian Capital Territory
Bankstown Hospital, Bankstown, New South Wales
Royal Prince Alfred Hospital, Camperdown, New South Wales
Concord Repatriation General Hospital, Concord, New South Wales
Liverpool Hospital, Liverpool, New South Wales
John Hunter Hospital, Newcastle, New South Wales
Westmead Hospital, Westmead, New South Wales
Sunshine Coast Hospital and Health Service, Birtinya, Queensland
Royal Brisbane and Women's Hospital, Herston, Queensland
Redcliffe Hospital, Redcliffe, Queensland
Royal Adelaide Hospital, Adelaide, South Australia
Box Hill Hospital, Box Hill, Victoria
Northeast Health Wangaratta, Wangaratta, Victoria
Royal Perth Hospital, Perth, Western Australia

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Population Health Research Institute
Registry
ClinicalTrials.gov
Start date
14 June 2019
Est. completion
1 December 2028

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇧🇷 Brazil 🇨🇦 Canada 🇩🇰 Denmark 🇫🇮 Finland 🇩🇪 Germany 🇮🇳 India 🇮🇹 Italy Nepal 🇳🇱 Netherlands 🇵🇰 Pakistan 🇰🇷 South Korea 🇪🇸 Spain 🇸🇪 Sweden 🇨🇭 Switzerland 🇬🇧 United Kingdom 🇺🇸 United States

14 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Incidence of Non-hemorrhagic stroke or systemic embolism; Incidence of vascular mortality, and non-fatal non-hemorrhagic stroke, myocardial infarction, peripheral arterial thrombosis, amputation, and symptomatic venous thromboembolism

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov