Multiple Sclerosis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with progressive Multiple Sclerosis (either primary or secondary progressive) by a neurologist or MS specialist centre
- People whose depression screening score (measured by a specific questionnaire called PROMIS) is above a certain threshold at the start of the trial
- People who are able to give their own consent to participate and are able to use a virtual reality (VR) headset at home
- For some groups in the trial (Groups 1 and 2): people who are currently receiving antidepressant medication (such as SSRIs or SNRIs) or talking therapy (psychotherapy) for depression
Who may not be able to join:
- People with severe thinking or memory difficulties, or significant vision problems, that could interfere with using VR equipment — this also includes people who experience agoraphobia (fear of open spaces), claustrophobia (fear of enclosed spaces), or motion sickness
- People who are currently taking part in another clinical trial focused on treating depression
- People with severe mental health conditions that require hospitalisation, or who are experiencing thoughts of suicide (passive or active), psychosis, or active misuse of alcohol or drugs
- People who have another neurological or autoimmune disease in addition to MS (confirm with trial site for specific details)
- People who require glasses or other vision correction, unless the prescription is mild (within ±1) or the person wears prescription contact lenses
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Hala Darwish, PhD, University of Michigan
Phone: 734- 764- 5249
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Changes to the Patient-Reported Outcomes Measurement Information System (PROMIS) Depression short form 8b scores; Virtual Reality (VR) Sessions completed over 8 weeks; Qualitative feedback on the VR Neuroscience Questionnaire during the intervention (groups 1 and 3); Qualitative feedback with Semi-structured interviews for participants that received VR; Enrollment rate; Retention rates; Adherence to VR intervention; Dropout reasons; Hardware/software issues
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.