Motor Neurone Disease Trial, Recruiting (NCT06551649)

Motor Neurone Disease Trial, Recruiting NCT06551649 Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Condition: Motor Neurone Disease

Printed from Voxsanity (voxsanity.com.au) — NCT06551649 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Motor Neurone Disease

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

People with ALS (a nervous system disease affecting muscle control) who are between 50 and 60 years old and have a similar age when their disease started and a similar length of time since diagnosis as other participants.
People with multiple sclerosis (MS) who have recently been diagnosed, are between 20 and 50 years old, and where the mix of male and female participants follows roughly a 2-to-1 female-to-male ratio.
Healthy volunteers who are spouses of patients, have no neurological (brain or nerve) diseases themselves, and are a similar age and gender to the patients they are matched with.

Who may not be able to join:

Anyone who does not agree to take part in the study.
MS patients who have been treated with medicines that affect the immune system or steroids, and whose MS is currently in an active (acute) phase.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 27 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ornella Parolini, Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Phone: +0630154464

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT06551649

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Phase: Not Applicable

Status: Recruiting

Condition: Motor Neurone Disease

Trial contact: +0630154464

More information: https://clinicaltrials.gov/study/NCT06551649

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

People with ALS (a nervous system disease affecting muscle control) who are between 50 and 60 years old and have a similar age when their disease started and a similar length of time since diagnosis as other participants.
People with multiple sclerosis (MS) who have recently been diagnosed, are between 20 and 50 years old, and where the mix of male and female participants follows roughly a 2-to-1 female-to-male ratio.
Healthy volunteers who are spouses of patients, have no neurological (brain or nerve) diseases themselves, and are a similar age and gender to the patients they are matched with.

Who may not be able to join:

Anyone who does not agree to take part in the study.
MS patients who have been treated with medicines that affect the immune system or steroids, and whose MS is currently in an active (acute) phase.

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 27 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Registry

ClinicalTrials.gov

Start date

17 January 2025

Est. completion

31 March 2026

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Neurite length measurement in a three-dimensional cellular model of amyotrophic lateral sclerosis.; Percentage of apoptotic cells in a three-dimensional cellular model of amyotrophic lateral sclerosis.; Area measurement of damaged myelin in a three-dimensional cellular model of multiple sclerosis.; Number of inflamed microglial cells in a three-dimensional cellular model of multiple sclerosis.; Neurite length measurement in amyotrophic lateral sclerosis organoids after treatment with human amniotic mesenchymal stromal cell secretome.; Percentage of apoptotic cells in amyotrophic lateral sclero...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov