Motor Neurone Disease
Clinical trials recruiting in Australia for Motor Neurone Disease, as the public registries list them.
Also called: ALS; Lou Gehrig's disease; Charcot disease; Lou Gehrig disease; Amyotrophic lateral sclerosis with dementia; Dementia with amyotrophic lateral sclerosis; Motor neuron disease, amyotrophic lateral sclerosis; JPLS; Juvenile PLS; PLSJ; Primary lateral sclerosis, juvenile
At a glance
12 trials recruiting in Australia
5 states or territories with a listed site
0 started recruiting in the last 30 days
328 trials recruiting overseas
15 October 2026 date last checked
Where the trials are
Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.
17 listed sites on this page do not say which state they are in, so the counts above are lower than the real number of sites in some states. The trials themselves are all listed below.
Trials for Motor Neurone Disease
12 of 12 trials shown.
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Not a phased study
Study for people with Motor Neurone Disease
Where- Online Patient Enrollment System, Sydney — Recruiting
Who can join Age child, adult, older adult. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Sanford HealthTimelineStarted 1 July 2010 Today 16 October 2026 Estimated completion 1 December 2100NCT01793168 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Motor Neurone Disease
Where- Flinders Medical Centre, Adelaide — Not yet recruiting
- The Prince Charles Hospital, Brisbane — Not yet recruiting
- Motor Neurone Disease Australia, Canberra — Not yet recruiting
- Austin Health, Melbourne — Recruiting
- Australian MND Registry, Melbourne — Not yet recruiting
- FightMND, Melbourne — Not yet recruiting
- Institute for Breathing and Sleep, Melbourne — Not yet recruiting
- Monash University, Melbourne — Not yet recruiting
- University of Melbourne, Melbourne — Not yet recruiting
- Sir Charles Gairdner Hospital, Perth — Not yet recruiting
- Macquarie University, Sydney — Not yet recruiting
- Royal Prince Alfred Hospital, Sydney — Not yet recruiting
- Westmead Hospital, Sydney — Not yet recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor University of MelbourneTimelineStarted 15 December 2021 Today 16 October 2026 Estimated completion 28 February 2026Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.
NCT05136222 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Motor Neurone Disease
Where- Concord Hospital, Sydney (NSW) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Mario Negri Institute for Pharmacological ResearchTimelineStarted 26 March 2025 Today 16 October 2026 Estimated completion 1 April 2027NCT06126315 · Checked 13 October 2026
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Recruiting Phase 2
Phase 2 study for people with Motor Neurone Disease
Where- Concord Repatriation General Hospital, Concord (NSW) — Recruiting
- Macquarie University, Sydney (NSW) — Recruiting
- Sunshine Coast University Hospital, Birtinya (QLD) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Regeneron PharmaceuticalsTimelineStarted 28 August 2024 Today 16 October 2026 Estimated completion 21 March 2032NCT06351592 · Checked 11 October 2026
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Recruiting Phase 2
Phase 2 study for people with Motor Neurone Disease
Where- Zydus 200, Caulfield South — Recruiting
- Zydus 201, Sydney (NSW) — Recruiting
- Zydus 202, Southport — Not yet recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Zydus Therapeutics Inc.TimelineStarted 17 September 2025 Today 16 October 2026 Estimated completion 1 March 2028NCT07023835 · Checked 11 October 2026
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Not yet recruiting Phase 1
Phase 1 study for people with Motor Neurone Disease
WhereNo Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.
- Sunshine Coast University Hospital, Birtinya (QLD) — this site's status is not stated on the record
- Flinders Medical Centre, Bedford Park (SA) — this site's status is not stated on the record
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Brain Trust BioTimelineStarted 15 August 2025 Today 16 October 2026 Estimated completion 15 June 2026Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.
NCT07093268 · Checked 11 October 2026
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Recruiting Phase 2
Phase 2 study for people with Motor Neurone Disease
Where- Novartis Investigative Site, Camperdown (NSW) — Withdrawn
- Novartis Investigative Site, Wollongong (NSW) — Recruiting
Who can join Age 18 Years and over. Sex Male participants only. Healthy volunteers Not accepted.Sponsor Novartis PharmaceuticalsTimelineStarted 13 January 2026 Today 16 October 2026 Estimated completion 2 August 2032NCT07190300 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Motor Neurone Disease
Where- Sydney Children's Hospital_Randwick, Randwick (NSW) — Recruiting
Who can join Age 0 Days to 42 Days. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor BiogenTimelineStarted 28 April 2026 Today 16 October 2026 Estimated completion 28 November 2028NCT07221669 · Checked 11 October 2026
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Recruiting Phase 2
Phase 2 study for people with Motor Neurone Disease
Where- Sydney Children's Hospital, Randwick, Randwick (NSW) — Recruiting
- Royal Children's Hospital, Parkville (VIC) — Not yet recruiting
Who can join Age 5 Years to 17 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor argenxTimelineStarted 19 December 2025 Today 16 October 2026 Estimated completion 28 May 2029NCT07287982 · Checked 15 October 2026
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Recruiting Phase 2
Phase 2 study for people with Motor Neurone Disease
Where- Concord Repatriation General Hospital, Concord (NSW) — Recruiting
- Neuroscience Research Australia, Randwick (NSW) — Recruiting
- Royal Brisbane and Women's Hospital, Brisbane (QLD) — Recruiting
- Flinders Medical Centre, Bedford Park (SA) — Recruiting
- Calvery Health care Bethlehem, Caulfield South (VIC) — Recruiting
- Perron Institute, Nedlands (WA) — Recruiting
Who can join Age 18 Years to 80 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Nura BioTimelineStarted 4 March 2026 Today 16 October 2026 Estimated completion 1 April 2027NCT07369076 · Checked 11 October 2026
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Recruiting Phase 1
Phase 1 study for people with Motor Neurone Disease
Where- Macquarie University Hospital, Sydney (NSW) — Recruiting
Who can join Age 18 Years to 80 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Celosia Therapeutics Pty LtdTimelineStarted 12 January 2026 Today 16 October 2026 Estimated completion 1 December 2027NCT07401121 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Motor Neurone Disease
Where- The Royal Melbourne Hospital, Melbourne — Recruiting
Who can join Age 21 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Synchron, Inc.TimelineStarted 22 May 2026 Today 16 October 2026 Estimated completion 1 March 2027NCT07533903 · Checked 11 October 2026
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voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice
0 selected. Choose 2 or 3 trials to compare them side by side.
Compare selected trialsTrials not shown here
Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.
Trials overseas
328 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
About Motor Neurone Disease
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages from your brain and spinal cord to your voluntary muscles - the ones you can control, like in your arms and legs. At first, this causes mild muscle problems. Some people notice: - Trouble walking or running - Trouble writing - Speech problems Eventually, you lose your strength and cannot move. When muscles in your chest fail, you cannot breathe. A breathing machine can help, but most people with ALS die from respiratory failure. The disease usually strikes between age 40 and 60. More men than women get it. No one knows what causes ALS. It can run in families, but usually it strikes at random. There is no cure. Medicines can relieve symptoms and, sometimes, prolong survival. NIH: National Institute of Neurological Disorders and Stroke
US source; availability in Australia may differ.
Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- ClinicalTrials.gov processing date: 8 October 2026.
- This page last checked by Voxsanity: 15 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
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