Stroke

Who might be able to join this trial: - You are a man or woman aged 18 or older who has been diagnosed with atrial fibrillation (an irregular heartbeat) - You are aged 75 or older - You have previously had a stroke - You have previously had a transient ischemic attack (TIA, sometimes called a "mini-stroke") or a blood...

**Who might be able to join this trial:** - You have a history of a type of irregular heartbeat called atrial fibrillation (AF) that comes and goes, is ongoing, or is permanent - You are 18 years of age or older (or the legal age of adulthood in your region) - Your doctor has determined that you are a suitable candidat...

Who might be able to join this trial: - People who are planned to receive a BIOTRONIK Implantable Cardiac Monitor (a small device placed under the skin to track heart activity). - People who are able to understand what the registry involves and are willing to sign a consent form. - People who are willing and able to us...

**Who might be able to join this trial:** - People who have had a recent brain bleed (called an intracerebral hemorrhage) in the upper part of the brain, where the bleed is at least 20mL in size - People aged 18 or older - People where surgery could begin within 8 hours of when symptoms first appeared, or within 8 hou...

**Who might be able to join this trial:** - People who are showing symptoms of a stroke affecting the back part of the brain (posterior circulation stroke), caused by a partial or complete blockage of a major artery at the base of the brain called the basilar artery. - Symptoms must have started — or the person must h...

**Who might be able to join this trial:** - Adults aged 18 or older who have had an ischemic stroke (a stroke caused by a blockage) with a large blood vessel blockage in the brain, confirmed by a CT or MRI scan of specific arteries (the internal carotid artery or the main middle brain artery) - People who are being tr...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of screening - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF) that is not caused by a faulty heart valve - People who have a medical reason to have a procedure to close off...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who are able to give written consent to participate (a large-print version is available for people with visual impairment, and an easy-to-read version is available for people who need extra support due to cognitive difficulties) - Peopl...

Who might be able to join this trial: - People who have been clinically diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel in the brain) - People aged 18 years or older - People whose stroke involves a blockage in the front part of the brain's blood supply (anterior circulation) - People...

Who might be able to join this trial: - People who have had a disabling stroke caused by a blood clot, who arrive for care within 4.5 hours of when their symptoms started (or when they were last seen to be well), and who may benefit from a clot-dissolving medication called tenecteplase given through a vein. - People wh...

Who might be able to join this trial: - Adults aged 18 years or older - People who have received a procedure to open blocked blood vessels in the brain (called endovascular therapy) within 24 hours of their stroke symptoms starting or when they were last known to be well - People whose blood pressure has remained high...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been clinically diagnosed with a stroke Who may not be able to join: - There are no general exclusion criteria listed at the overall trial level — however, each specific section of the trial has its own additional require...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with a spontaneous brain bleed (bleeding in the brain that was not caused by an injury), confirmed by a CT scan without contrast dye - People who are within 24 hours of when their symptoms started, or within 24 hours...

Who might be able to join this trial: - People aged between 18 and 80 years old - People who have been diagnosed with a spontaneous brain bleed (not caused by injury or another known condition) in the upper part of the brain, confirmed by a brain scan - People who arrived at hospital within 24 hours of their symptoms s...

**Who might be able to join this trial:** - People aged 18 years or older - People who have had an acute ischaemic stroke (a stroke caused by a blockage) involving two connected blockages — one in a blood vessel inside the brain and one in the main artery in the neck, where the neck blockage is thought to be caused by...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been assessed as needing a transcatheter aortic valve replacement (a minimally invasive procedure to replace a heart valve) - People who are willing to attend follow-up appointments as outlined in the study plan - People w...

Who might be able to join this trial: - Adults aged 22 years or older - People who are showing sudden neurological symptoms (such as weakness, speech problems, or facial drooping) that are suspected to be a stroke, with symptoms starting within the last 24 hours - People whose participation in the scan would not cause...

**Who might be able to join this trial:** - People who are able to read and understand the consent form, and who are willing to sign it - Men and women between 18 and 65 years old (inclusive) at the time of signing the consent form - People with no significant past or current health problems affecting the heart, liver...

Who might be able to join this trial: - People who are 18 years of age or older - People who have come to a participating hospital emergency department, intensive care unit, or inpatient unit because they have had, or are at risk of having, a stroke, mini-stroke (TIA), or another problem affecting blood flow to the bra...

Who might be able to join this trial: - Children from birth to 18 years of age who have been diagnosed with a stroke after January 1, 2003, at one of the participating trial sites - Children diagnosed with arterial ischemic stroke (a stroke caused by a blocked artery in the brain) - Children diagnosed with cerebral sin...

Who might be able to join this trial: - People who are 18 years of age or older - People who have lived in the area near the recruitment centre for at least 6 months - People who have been diagnosed with a spontaneous brain bleed (one that occurred without an obvious outside cause) - People whose brain bleed was not ca...

Who might be able to join this trial: - People who are 18 years of age or older - People who speak German - People who have had their first ever ischemic stroke (a stroke caused by a blocked blood vessel in the brain), with the stroke having started within the last 7 days - People who are willing to sign a written cons...

Who might be able to join this trial: - You must be available and able to participate in follow-up visits and check-ins for 5 years Who may not be able to join: - People who pass away during the study from causes not related to heart or blood vessel disease would be excluded from final results (confirm with trial site...

Who might be able to join this trial: - People who have a brain arteriovenous malformation (AVM), which is an abnormal tangle of blood vessels in the brain. Who may not be able to join: - People whose brain AVM has caused bleeding that is putting pressure on the brain and requires surgery to treat. However, if surgery...

**Who might be able to join this trial:** *For stroke survivors:* - People who had a stroke at least 3 months ago (sub-acute) or at least 6 months ago (chronic) - People with a score above 24 out of 30 on a standard memory and thinking test, indicating normal cognitive ability - People with mild to moderate disability...

Who might be able to join this trial: - People who have had their first stroke (either a bleed in the brain or a blockage) on one side only, from 24 hours after being admitted to hospital up to one year after the stroke occurred - People who have weakness or paralysis on one side of their body as a result of a stroke -...

**Who might be able to join this trial:** - People who have been fully informed about the study, its goals, what it involves, and their rights as a participant, and who have freely agreed to take part by signing a consent form - People who are covered by a health insurance plan - People who are able to attend follow-up...

Who might be able to join this trial: - People who have been diagnosed with an acute intracranial artery dissection (a tear in an artery inside the skull) with symptoms that started within the last 30 days - People who are 18 years of age or older - People who have given consent to participate, following the rules requ...

Who might be able to join this trial: - People who have been diagnosed with cerebral vascular disease (a condition affecting the blood vessels in the brain), regardless of gender, age, ethnicity, stage of disease, or current treatment. - People for whom follow-up medical information is expected to be available over the...

Who might be able to join this trial: - People who have had a stroke and are still experiencing difficulty swallowing 12 weeks after their stroke (anywhere between 9 and 15 weeks after the stroke) Who may not be able to join: - Stroke patients who also have neurological or psychiatric conditions, or any other illness...

Who might be able to join this trial: - People over 70 years old who have severe narrowing of the aortic heart valve and whose doctors have determined they need a non-surgical valve replacement procedure called TAVI (where a new valve is inserted through a blood vessel rather than open-heart surgery) Who may not be ab...

**Who might be able to join this trial:** - You are 18 years old or older - You are willing and able to sign a written consent form to participate - You are having a major abdominal operation lasting 3 hours or more, such as major bowel or stomach surgery (for example, removal of part of the pancreas, stomach removal,...

**Who might be able to join this trial:** **Volunteers:** - People who have given their informed consent to participate in the trial **Stroke patients:** - People who have given their informed consent to participate in the trial - People who have had a new stroke in a specific area of the brain (above the brainstem),...

Who might be able to join this trial: - Adults who are generally healthy with no significant medical conditions - People between 18 and 45 years of age - People who have been living in Calgary for at least the past one year - People who are not taking any blood pressure medications - People who are able to tolerate lac...

**Who might be able to join this trial:** - People aged between 21 and 75 years - People who have had one stroke on one side of the brain (not the brainstem or cerebellum), either caused by a blocked blood vessel or bleeding in the brain - People who have had only one stroke (no previous strokes before this one) - Peop...

Who might be able to join this trial: **Healthy younger adults (ages 18–49):** - People aged 18 to 49 years old. - People who are willing and able to give informed consent to participate. - People whose muscles in the upper arm or hand respond to a type of brain stimulation called TMS, as checked during a screening se...

**Who might be able to join this trial:** *For the Symptomatic Group (people who have had a stroke or related event):* - People between 30 and 85 years of age - People who have had a recent stroke shown on a specific type of brain scan (MRI), caused by a clot travelling from a narrowed artery in the brain (at least 60...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have had a stroke - People who are still experiencing symptoms caused by that stroke **Who may not be able to join:** - No specific exclusion criteria were listed in the provided information (confirm with trial site) **Im...

**Who might be able to join this trial:** - People who have been diagnosed with an acute ischemic stroke (a stroke caused by a blood clot blocking blood flow to the brain) - People who are eligible for, and have already received, clot-dissolving medication given through a drip (intravenous thrombolysis), started within...

**Who might be able to join this trial:** **For people who had a stroke at least 6 months ago (Chronic stroke group):** - People who have weakness or limited movement on one side of the body as a result of their first-ever stroke, which happened at least 6 months before the screening appointment - People with severe d...

Who might be able to join this trial: - People aged between 18 and 70 years old (inclusive) - People who have a permanent pacemaker or implanted defibrillator already fitted that is capable of pacing both the upper and lower chambers of the heart - People whose heart is pumping at more than 50% of its normal capacity (...

Who might be able to join this trial: - People who are right-handed - People who speak English as their only language - People who have had a single stroke affecting the left side of the brain - People who are at least six months past their stroke - People who have been clinically diagnosed with apraxia of speech (a mo...

Who might be able to join this trial: - People aged between 18 and 90 years old - People who have weakness in an arm or hand following an ischemic (blockage) or hemorrhagic (bleeding) stroke, measured by a standard stroke assessment tool - People who are able to follow simple instructions given in English - People who...

Who might be able to join this trial: - You must be showing signs and symptoms of an acute (sudden) ischemic stroke (a stroke caused by a blocked blood vessel in the brain) - You must be 18 years old or older - Your stroke must be rated at least 6 on a standard stroke severity scale, meaning it is causing noticeable di...

Who might be able to join this trial: - People aged 18 years or older - People who have had a recent neurological problem (such as weakness, numbness, or difficulty speaking) that started less than 15 days ago, caused by a small stroke in a deep part of the brain - People whose brain MRI scan confirms a recent small, d...

Who might be able to join this trial: - The person must agree to take part and sign a consent form - There must be a blockage in one of the major blood vessels supplying the brain, confirmed by a special scan (CTA or MRA), in specific locations in the front or back part of the brain's blood supply - A brain scan must s...

**Who might be able to join this trial:** This trial has several different groups. You may qualify for one of the following: **Group 1a:** - You have a history of atrial fibrillation (an irregular heartbeat condition) **Group 1b:** - You have a history of atrial fibrillation, AND you are already scheduled for a hear...

**Who might be able to join this trial:** - You have recently had a stroke caused by a blocked blood vessel, or a "mini-stroke" (a brief stroke-like episode that goes away quickly) with a risk score of 3 or higher on a standard medical scale - You are 40 years of age or older - You have high blood pressure, either diag...

Who might be able to join this trial: - You are between 18 and 85 years old - You have had a single stroke on one side of the brain, confirmed by an MRI or CT scan, that happened more than 6 months ago - Your stroke has affected your ability to move your eyes or head, and caused some arm or leg weakness, as measured by...

**Who might be able to join this trial:** - Adults aged 18 or older - People who had a stroke with a certain level of severity (measured by a standard stroke scale), assessed either within 16 hours or between 16 and 24 hours after they were last known to be well - People whose stroke is caused by a blockage in one of...

**Who might be able to join this trial:** - People aged between 18 and 80 years old - People whose stroke symptoms began within the past week - People with a stroke severity score of 12 or less on a standard medical scale called the NIHSS - People who have been confirmed to have had an ischemic stroke (caused by a bloc...

**Who might be able to join this trial:** - People who have been diagnosed by a neurologist with an ischemic stroke that is believed to have come from an unknown source (called an embolic stroke of undetermined source, or ESUS), within the past 365 days before joining the trial. - People who have a small natural openin...

**Who might be able to join this trial:** - People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) on the left side of the brain - People who spoke English fluently before their stroke, by their own report - People who are able to give informed consent themselves, or who have a legall...

**Who might be able to join this trial:** - People aged 21 or older - People who had their first stroke (either a bleeding stroke or a blockage stroke) at least 6 months ago - People who are able to follow a simple 3-step instruction and remember 2 out of 3 items after a 30-minute delay - People who have full movement...

**Who might be able to join this trial:** - People between 18 and 90 years of age. - People who are able to understand and follow instructions given in English. - People who have been diagnosed with a neurological condition — specifically stroke, Parkinson's disease, or Multiple Sclerosis — for at least 6 months befor...

Who might be able to join this trial: - You are between 18 and 90 years old when you join the study - It has been more than 6 months since your first stroke (either a blockage or bleeding type of stroke) - You have significant weakness in one hand and wrist, meaning you cannot fully extend your wrist, thumb, or fingers...

**Who might be able to join this trial:** - You must live in the city of Hamburg at the time you join the study - You must be between 45 and 74 years old - You must be willing and able to sign a consent form agreeing to take part in the study **Who may not be able to join:** - You may not be able to join if you do not...

**For Stroke Patients:** Who might be able to join this trial: - People who had a stroke more than 6 months ago - People between 18 and 90 years old - People whose brain scan shows evidence of a stroke Who may not be able to join: - People who have difficulty understanding or following instructions - People with a hi...

Who might be able to join this trial: - Adults aged 18 or older who have had heart bypass surgery (CABG) on its own, not combined with other procedures - People who develop a type of irregular heart rhythm called atrial fibrillation after their bypass surgery, where the irregular rhythm either lasts more than 60 minute...

Who might be able to join this trial: **For stroke patients:** - Adults between 18 and 80 years old who have had a stroke more than 3 months ago - People who have given their written agreement to take part in the study **For healthy volunteers (no stroke history):** - Adults between 18 and 80 years old - People who h...

Who might be able to join this trial: - People who have recently had a stroke (either a blocked blood vessel type or a bleeding in the brain type) and are in the early recovery phase. - People who were transferred directly from an acute hospital to an inpatient rehabilitation program at the trial's institute. Who may...

**Who might be able to join this trial:** - People who have had an acute brain injury — such as an ischemic or hemorrhagic stroke (including a burst aneurysm), traumatic brain injury, brain damage after cardiac arrest, or a brain tumour — that required admission to intensive care and breathing support through a tube i...

**Who might be able to join this trial:** *For patients:* - People who have had a stroke or a transient ischaemic attack (a brief, stroke-like episode) that meets certain medical severity criteria, as assessed by the trial site - People whose level of disability after stroke or TIA is mild (a score of 2 or less on a s...

**Who might be able to join this trial:** - People aged 18 or older - People who have weakness or loss of movement on one side of the body (in one arm or leg) caused by a stroke that affected one specific area of the brain, where the stroke occurred between 4 and 10 weeks before the start of the study - People whose wr...

**Who might be able to join this trial:** - People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) confirmed by a brain scan within 48 hours of their symptoms starting - People who are within 5 days of when their stroke symptoms first began - People who have been found to have moderate...

**Who might be able to join this trial:** - People who are right-handed (for stroke survivors, this means right-handed before the stroke occurred) - People who have completed high school or an equivalent level of education - People who speak English as their first language and were not exposed to a second language bef...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with an acute (sudden onset) stroke caused by a blocked blood vessel in the brain, confirmed by specific brain scans (MRI and CT scan) - People whose stroke symptoms began within the last 72 hours (3 day...

Who might be able to join this trial: - Adults between 18 and 70 years old, both male and female - People who have a single, specific area of brain damage in one region of the brain (for example, from a stroke or after brain surgery), confirmed by an MRI scan - People with enough intellectual ability and language under...

Who might be able to join this trial: - People aged 18 or older - People who have recently had a stroke - People who have been admitted to an inpatient rehabilitation facility - People who have been identified as having neglect (a condition where someone has difficulty paying attention to one side of their body or surr...

**Who might be able to join this trial:** - People aged 18 or older - People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) involving a blockage in one of the major blood vessels supplying the front part of the brain, and who were assessed as suitable for a procedure to mechanically...

Who might be able to join this trial: **Healthy younger adults (ages 18–55):** - People aged 18 to 55 years - People with no diagnosed neurological, heart, lung, muscle, bone, or other ongoing or sudden health conditions - People who have not had major surgery in the last 6 months or a hospital stay in the last 3 mont...

**Who might be able to join this trial:** - People who have been diagnosed with a stroke - People who speak, read, and write in Turkish - People whose hand function is at level 4, 5, or 6 according to the Brunnstrom scale (a measure of movement and muscle control recovery after stroke — confirm with trial site if unsur...

Who might be able to join this trial: - People who have been diagnosed with a stroke and are either currently admitted to the Shirley Ryan AbilityLab or had a stroke in the past and are living in the community. - Healthy individuals with no known significant health problems may also be able to join as a comparison grou...

Who might be able to join this trial: - People who are having their first coronary artery bypass surgery done without the use of a heart-lung bypass machine (known as "off-pump"), and this is the only procedure being performed Who may not be able to join: - People who currently have, or have had in the past, an irregu...

**Who might be able to join this trial:** - People aged 18 years or older. - People who have been confirmed to have an acute (sudden-onset) ischemic stroke, shown by specific brain scans — an MRI and a CT scan — that identify a new area of damage in the brain. - People who are within 24 hours of when their stroke sympt...

Who might be able to join this trial: **For people without stroke (control participants):** - People between 45 and 90 years of age - People with sufficient language and thinking skills to take part in training and testing - People who are in stable enough health to participate in the study - People who speak English...

**Who might be able to join this trial:** **Healthy Volunteers:** - You are between 18–35 years old (Group 1) or between 50–80 years old (Group 2) - You speak English - You are strongly right-hand dominant (you almost always use your right hand for tasks) - You have a normal neurological exam as confirmed by the study...

**Who might be able to join this trial:** - People who are 21 years of age or older at the time of joining - People who have weakness on one side of the body affecting arm movement, caused by their first-ever stroke, that occurred at least 6 months before the screening visit - People whose arm movement is rated as seve...

**Who might be able to join this trial:** **For healthy volunteers (people who have not had a stroke):** - People aged 18 or older - People who speak and understand English fluently - People with no history of neurological conditions (such as epilepsy or Parkinson's disease) or psychiatric conditions (such as schizoph...

**Who might be able to join this trial:** - You are 50 years of age or older - You have recently had an ischemic stroke (caused by a blockage) within the last 72 hours, confirmed by a specific type of brain scan called an MRI - The stroke affected either the outer layer of the brain (cortex) or a deeper area within the...

**Who might be able to join this trial:** - People who have had a bleeding stroke (hemorrhagic stroke) confirmed by a CT or MRI scan - People who have been in a reduced state of consciousness for more than 4 weeks since their stroke occurred - People who are in a vegetative state or a minimally conscious state, as meas...

Who might be able to join this trial: - You must be 18 years old or older - You must have had one or more strokes, with your most recent stroke happening at least six months ago - You must have weakness in your arm or hand that makes it hard to do everyday tasks with the affected hand - All the fingers on your affected...

Who might be able to join this trial: - People who are in early neurological rehabilitation (sometimes called "phase B" rehabilitation) - People who have had a stroke, a traumatic brain injury, or a brain injury caused by lack of oxygen - People who have a disorder of consciousness, such as being in a coma, an unrespon...

Who might be able to join this trial: - People aged between 20 and 75 years old. - People who have had their first stroke (either caused by a blocked blood vessel or a bleed in the brain) on one side of the body, with the stroke happening more than 3 months ago. - People with moderate to severe weakness or movement dif...

**Who might be able to join this trial:** - People aged 60 or under who have been diagnosed with a stroke or mini-stroke (TIA) where no clear cause was found (called a "cryptogenic" stroke or TIA) - People who have already had a successful procedure to close a small hole in the heart called a PFO (patent foramen ovale)...

Who might be able to join this trial: - People who are over 18 years old - People who have had their first stroke affecting one side of the brain, with the stroke occurring more than 3 months ago - People who still have walking difficulties affecting one side of the body as a result of their stroke (such as an abnormal...

"Who might be able to join this trial: - People who are currently experiencing an acute stroke (a stroke that is happening or has just happened recently) Who may not be able to join: - No specific exclusion criteria have been listed for this trial (confirm with trial site) Important: Always verify eligibility with th...

Who might be able to join this trial: - People who are already included in the Dijon Stroke Registry and have not objected to taking part in the study Who may not be able to join: - People who are under 18 years of age - People who have stated that they do not wish to participate in the study Important: Always verify...

**Who might be able to join this trial:** - People aged between 18 and 85 years old - People who have been diagnosed with an acute ischaemic stroke (a stroke caused by a blocked artery) affecting the front part of the brain, involving a major artery such as the internal carotid artery or middle cerebral artery - People...

**Who might be able to join this trial:** - People aged between 18 and 85 years old - People who are able to walk at least 10 metres on their own, with or without a walking aid such as a cane or walker - People who had a stroke at least 6 months ago - People who have a caregiver available to help with at-home training...

Who might be able to join this trial: - People aged between 18 and 64 years old - People who have been clinically diagnosed with a first or repeated stroke, either the type caused by a blocked blood vessel or the type caused by bleeding in the brain - People who are living at home after being discharged from hospital f...

**Who might be able to join this trial:** - You must have already been treated with the NeVa thrombectomy device (a clot-removal tool) before being considered for this trial. - You are 18 years of age or older. - Your stroke symptoms are assessed as moderately severe or worse on a standard stroke scale (NIHSS score of...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been admitted to the Pitié-Salpêtrière stroke unit - People who have had a stroke that has caused weakness or movement problems in one or both arms - People who have agreed to take part in the trial **Who may not be a...

Who might be able to join this trial: - People who are being assessed for a possible acute stroke - People who have been admitted to a stroke unit Who may not be able to join: - People who are under 18 years of age Important: Always verify eligibility with the trial site directly before applying.

**Who might be able to join this trial:** - Adults aged 18 or older - People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) and whose treating doctor has determined them to be suitable for a procedure to open the blocked vessel (endovascular treatment) - People who have given their si...

**Who might be able to join this trial:** - Adults aged 18 to 80 years old - People who have had a blockage in a large artery supplying the front part of the brain (confirmed by a special type of brain scan called a CTA or MRA) - People whose stroke symptoms started less than 24 hours before the brain scan was taken -...

**Who might be able to join this trial:** - People who had a stroke on the left side of the brain (either a blocked blood vessel or a bleed) at least 12 months before joining the trial. - People who have spoken English as their primary language for at least the last 20 years. - People who are able to give their own co...

**Who might be able to join this trial:** - People who are 18 years of age or older, or who meet the legal age for giving consent in their country or state. - People who score 10 points or higher on a standard stroke severity scale (called the NIHSS) measured before being enrolled in the trial. - People who had little...

**Who might be able to join this trial:** **Main patient group (experimental group):** - People of any gender who have had a severe bleeding or blockage stroke, or brain injury caused by lack of oxygen after cardiac arrest and resuscitation, and are being treated at the Institute of Intensive Care Medicine at Universi...

Who might be able to join this trial: - People who had a stroke at least 6 months ago and whose overall health is currently stable - People who had a single stroke on one side of the brain only, with no restrictions on whether it was a bleeding or blockage type of stroke, or how large it was - People who have some meas...

**Who might be able to join this trial:** - People who have had a stroke at least 6 months ago and are currently in a stable medical condition - People who have had a single stroke affecting one side of the body only (both ischemic — caused by a blockage — and hemorrhagic — caused by bleeding — strokes are considered,...

**Who might be able to join this trial:** - People who had a stroke at least 6 months ago and whose health is currently stable - People who had a single stroke on one side of the brain only (either a bleeding stroke or a blocked blood vessel stroke, of any size) - People who have some detectable stiffness or tightness...

**Who might be able to join this trial:** - People aged 18 to 70 years old (or 18 to 65 for the dose escalation part of the trial) at the time of signing the consent form - People who have muscle stiffness and weakness on one side of the body (spastic hemiparesis) caused by a stroke or traumatic brain injury - People...

**Who might be able to join this trial:** **Healthy volunteers:** - Adults between 18 and 75 years of age who do not have a physical disability or health condition that would prevent them from completing physical tasks in the study - People who are proficient in English, as the study requires following spoken instruct...

Who might be able to join this trial: - People who have had an ischemic stroke (caused by a blockage) affecting the front part of one side of the brain - People who are 18 years of age or older - People who are at least 5 days past their stroke but no more than 8 weeks past their stroke when treatment starts - People w...

**Who might be able to join this trial:** - People who have a medical reason to have a left atrial appendage closure (a procedure to close off a small pouch in the heart) and are having this procedure done at Gottsegen National Cardiovascular Center between 10 March 2021 and 31 December 2025 - People aged 18 years or o...

**Who might be able to join this trial:** - People who have had a stroke on one side of the brain only - People whose stroke happened more than 6 months ago - People whose weakness or paralysis affects only one side of their body - People who are able to walk on their own, with or without a walking aid such as a cane o...

Who might be able to join this trial: - People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel in the brain) - People between 18 and 65 years of age Who may not be able to join: - People who had a transient ischemic attack (a brief, temporary stroke-like episode) that did not progress...

Who might be able to join this trial: - You have had a stroke recently, within the last one month. Who may not be able to join: - Your stroke happened more than one month ago. Important: Always verify eligibility with the trial site directly before applying.

Who might be able to join this trial: - People who have had their first-ever stroke on the left side of the brain, within the last 3 months before joining the study, or people who are healthy volunteers with no history of stroke - People aged between 18 and 80 years old - People who were fluent in English and able to r...

**Who might be able to join this trial:** **Stroke patients may be eligible if they:** - Are under 80 years old - Score above 24 on a standard memory and thinking test (Mini Mental State Examination) - Have a moderate level of disability — able to do some things independently but with some limitations (Modified Rankin...

**Who might be able to join this trial:** - A person who has given written agreement to take part (or whose legal representative has done so) before any study procedures begin. - People aged between 18 and 80 years old at the time of signing the consent form. - People who were admitted to hospital within 48 hours of t...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with a stroke - For the main study group: people who are within the first 4 months after their stroke occurred, starting from the day after the stroke - For the primary care group: people who are at least 3 months aft...

**Who might be able to join this trial:** - Your stroke symptoms fall within a specific range of severity — not too mild and not too severe — based on a standard stroke scale score (confirm with trial site) - Before this stroke, you were mostly able to manage daily activities independently (based on a disability scori...

**Who might be able to join this trial:** - People who score below 45 on a balance assessment called the Berg Balance Scale (a test of standing and moving balance) - People whose natural walking speed over 10 metres is slower than 0.8 metres per second (a relatively slow walking pace) - People who have had a stroke aff...

Who might be able to join this trial: - People who are adults (18 years of age or older) - People who have had a stroke caused by a blockage in a large blood vessel in the brain Who may not be able to join: - People who have bleeding in the brain, a brain tumor, an aneurysm (a bulge in a blood vessel), or an abnormal...

**Who might be able to join this trial:** - You have had a minor stroke or a TIA (sometimes called a "mini-stroke") and do not need rehabilitation after leaving hospital, but could benefit from physical activity to help protect your heart and blood vessels - You currently spend 5 hours or less per week doing intense ph...

**Who might be able to join this trial:** - You are between 18 and 85 years old - You have had an ischemic stroke (a stroke caused by a blocked blood vessel) within the last 30 days, linked to a 70%–99% narrowing of a major artery inside the brain, as seen on a special scan called a CTA - The affected blood vessel meas...

Who might be able to join this trial: - People who have been diagnosed with a confirmed acute Type A aortic dissection (a serious tear in the main blood vessel leaving the heart). - People who have been accepted to have surgery to repair the dissection. Who may not be able to join: - People who are showing new neurolo...

**Who might be able to join this trial:** - The patient or their caregiver has given approval to participate - A stroke (either caused by a blocked blood vessel or by bleeding in the brain) has been confirmed using a brain scan such as a CT or MRI - At least one muscle in the upper arm or hand is significantly stiff or...

Who might be able to join this trial: - People who are already taking part in the CUHK Brain Health Longitudinal Study and who had an MRI brain scan completed at the start of that study Who may not be able to join: - People who had a stroke or dementia that was diagnosed by a doctor before joining the study - People w...

Who might be able to join this trial: - People who are having surgery for a blood vessel problem in the brain or spinal cord - People who are between 1 and 120 years of age Who may not be able to join: - There are no stated exclusion criteria for this trial Important: Always verify eligibility with the trial site dir...

**Who might be able to join this trial:** - People who are eligible for a procedure to remove a blood clot blocking a large blood vessel in the brain (called endovascular thrombectomy) - People who are eligible for a procedure to widen narrowed blood vessels in the brain after a type of brain bleed caused by a burst an...

Who might be able to join this trial: - Babies whose corrected age (counting from their original due date) is between full-term birth age and 24 months old at the time of joining the study - Babies who have had a confirmed brain injury shown on a scan, such as a stroke around the time of birth, bleeding in the brain, o...

**Who might be able to join this trial:** - Adults between 18 and 95 years of age who have had a blockage in a specific artery in the brain (the internal carotid artery or a main branch of the middle cerebral artery). - People whose stroke symptoms were measured as moderately severe or worse on a standard stroke scale...

**Who might be able to join this trial:** - People aged 18 or older who are able to give written agreement to take part in the study - People who have been clinically diagnosed with an ischemic stroke (a stroke caused by a blockage, not bleeding) or a transient ischemic attack (TIA, sometimes called a "mini-stroke"),...

**Who might be able to join this trial:** - People aged between 18 and 90 years old - People weighing between 40 kg and 166 kg - People for whom treatment can begin within 24 hours of when they were last known to be well before their stroke symptoms started - People whose stroke severity score (measured by a standard...

Who might be able to join this trial: - People who have had a stroke recently (within approximately 15 to 30 days of the stroke occurring) - People who are experiencing their first ever stroke - People who have weakness on one side of their body as a result of the stroke - People who are currently staying in a hospital...

**Who might be able to join this trial:** - You are 18 years of age or older - You have had your first-ever stroke (either a blockage-type or bleeding-type stroke) that damaged the main vision area of the brain, causing you to lose vision in part of your visual field - Brain scans (MRI or CT) show that some vision-rel...

Who might be able to join this trial: - People who have had a stroke on the left side of the brain, either from a blocked blood vessel or a bleed, and whose stroke is considered long-term (chronic) - People who spoke English fluently before their stroke, based on their own report - People aged 18 or older - People who...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been confirmed to have an acute (sudden-onset) ischemic stroke, shown by specific brain scan results (both an MRI and a CT scan showing a new area of damage) - People who are within 72 hours (3 days) of when their stroke s...

Who might be able to join this trial: - People who have been clinically diagnosed with an acute ischemic or hemorrhagic stroke (a stroke caused either by a blocked blood vessel or bleeding in the brain) - People who were admitted to hospital within 12 hours of their stroke - People between the ages of 18 and 45 years o...

Who might be able to join this trial: - People who are 70 years old or older. - People who have been diagnosed with an ischemic stroke (a stroke caused by a blood clot) or a TIA (sometimes called a "mini-stroke") within the last 14 days. Who may not be able to join: - People who have already been diagnosed with atrial...

**Who might be able to join this trial:** - People aged 18 to 85 years old, both male and female - People who had little to no disability in daily life before their stroke (confirm with trial site regarding the specific scoring measure used) - People who have been diagnosed with either an ischemic (blockage) or bleedi...

Who might be able to join this trial: - Adults between the ages of 50 and 75 years old - People who have never had a stroke, a mini-stroke (TIA), or heart disease - People whose top blood pressure number (systolic) is between 121 and 139 mmHg - People who have one or more lifestyle risk factors, such as smoking, being...

Who might be able to join this trial: - People who have been diagnosed with a stroke - People who are willing and able to understand and sign a written consent form Who may not be able to join: - People who currently have an active infection - People who currently have active cancer - People who have chronic failure o...

Who might be able to join this trial: - Adults aged 18 years or older - People who are willing and able to give written consent and follow the study procedures - People who had their stroke at least 6 months ago - People who have weakness or paralysis on one side of the body caused by a single stroke - People who need...

**Who might be able to join this trial:** - People who have recently had a stroke in a specific area of the brain (the Middle Cerebral Artery region) that has caused weakness or partial paralysis on one side of the body - People whose stroke was either caused by a bleed in the brain or a blockage in a blood vessel - Pe...

**Who might be able to join this trial:** - People aged 18 or older - People who have had a stroke at least 8 months ago, where the stroke affected the primary motor area of the brain - People who have weakness or partial paralysis on one side of the body (called hemiparesis) - People who retain some ability to move bo...

Who might be able to join this trial: - People who have been diagnosed with Broca's aphasia or mixed aphasia, as determined by a Speech-Language Pathologist - People whose stroke caused damage only in the left side of the brain, confirmed by a CT or MRI scan - People who are in the chronic stage of recovery, meaning th...

**Who might be able to join this trial:** - Adults aged 18 or older who have had an acute ischemic stroke (a stroke caused by a blockage), with symptoms starting within one week before being admitted to hospital - People whose brain MRI scan shows clear evidence of an ischemic stroke (strokes that do not show up on ima...

**Who might be able to join this trial:** - People who have had an acute ischemic stroke (a stroke caused by a blockage) and are eligible to receive a clot-dissolving medication given through a vein within 4.5 hours of the stroke starting. - People who had little to no physical disability before the stroke occurred. -...

**Who might be able to join this trial:** - You have had an acute stroke caused by a blocked blood vessel, and you are not eligible for the standard clot-busting injection (because too much time has passed) or for a procedure to physically remove the clot (because the blockage is not in one of the main large arteries)...

**Who might be able to join this trial:** - People who have been diagnosed with an ischemic stroke (a stroke caused by a blocked blood vessel) or a transient ischemic attack (TIA, sometimes called a "mini-stroke"), confirmed by a CT or MRI brain scan. - People whose stroke or TIA symptoms began less than 90 days ago. -...

**Who might be able to join this trial:** - People who have had a stroke, including a blocked blood vessel in the brain (cerebral infarction), bleeding inside the brain (intracerebral hemorrhage), or bleeding around the brain (subarachnoid hemorrhage) **Who may not be able to join:** - People with cancer that has spre...

**Who might be able to join this trial:** - People who have had an ischemic stroke (a stroke caused by a blocked blood vessel) that started less than 1 day before being admitted to hospital - People whose stroke affected specific areas of the brain supplied by one of three main brain arteries (the anterior cerebral ar...

**Who might be able to join this trial:** - People who have had heart failure for at least 6 months, with symptoms that are stable (not in crisis), where the heart failure is caused by blocked arteries, inflammation, or a genetic heart condition - People who are willing to sign a consent form agreeing to take part in t...

Who might be able to join this trial: - You have been experiencing shoulder pain on your affected (weaker) side after a stroke or similar condition for at least 3 months - You have moderate to significant shoulder pain (scoring more than 3 out of 10) when someone gently moves your affected shoulder for you Who may not...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have had an ischemic stroke (a stroke caused by a blocked blood vessel) confirmed by an MRI scan - People whose stroke involves a blockage in a specific large artery in the brain (known as the M1 and/or M2 segments) - People for whom doct...

Who might be able to join this trial: - People who have had their first stroke (either a blockage or bleed in the brain) less than 3 years ago and whose condition is now medically stable. - People who are no longer receiving active treatment for their stroke. - People with normal vision, or vision that is fully correct...

Who might be able to join this trial: - People who have had a stroke caused by a blockage in one of the major blood vessels at the front of the brain (specifically the internal carotid artery or middle cerebral artery), and who are receiving a procedure to physically remove that blockage. Who may not be able to join:...

Who might be able to join this trial: - The stroke must have occurred less than 72 hours ago - People must be older than 18 years of age Who may not be able to join: - People who have bleeding in the brain, confirmed by a CT or MRI scan - People who have a current or past immune system disease, or another serious heal...

Who might be able to join this trial: - People who have experienced at least some weakness on one side of their body (including one leg) following a brain injury such as a stroke or traumatic brain injury - People who speak French - People who are enrolled in the French social insurance system - People who had no previ...

**Who might be able to join this trial:** - You have had an ischemic stroke (a stroke caused by a blood clot) in the past four weeks, confirmed by a brain scan (CT or MRI) or a doctor's assessment - It is possible for you to begin the trial treatment within four weeks of your stroke, when your doctors feel it is safe t...

Who might be able to join this trial: - People who have had their first-ever stroke caused by a blocked artery on the left side of the brain, confirmed by an MRI scan - People who are at least 3 months past the date their stroke occurred - People who have a type of language difficulty called non-fluent aphasia, confirm...

**Who might be able to join this trial:** **Phase 1:** - Adults who are medically stable with no health problems that would prevent them from taking part in stroke rehabilitation - People who have had a stroke (either a blocked or bleeding blood vessel in the brain) more than 3 months ago, where the stroke has affecte...

**Who might be able to join this trial:** - Adults aged 18 or older - People who are presenting between 24 and 72 hours after their stroke began, or after they were last seen to be well - People who have been diagnosed with an acute ischaemic stroke caused by a blockage in one of the major arteries at the front of the...

**Who might be able to join this trial:** - People aged 18 years or older - People who have had a stroke caused by a blockage (not bleeding) on one side of the brain that is causing symptoms; a second silent (symptom-free) stroke on the other side is still permitted - People who have weakness in the shoulder and/or fin...

Who might be able to join this trial: - People who are within 2 months of having a stroke Who may not be able to join: - People who have restrictions on putting weight through their legs, such as an amputation or a broken bone in the leg or foot - People who were not able to walk more than 50 metres before their most...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been admitted to hospital because of an ischemic stroke (a stroke caused by a blocked blood vessel) - People for whom a signed informed consent form has been completed **Who may not be able to join:** - People whose m...

**Who might be able to join this trial:** - People who have been diagnosed with a stroke that occurred on the left side of the brain - People whose consent date is at least 1 month after their stroke happened - People who are right-handed - People who are fluent in English - People who are 18 years of age or older **W...

**Who might be able to join this trial:** - People who have had a stroke confirmed by brain imaging (MRI or CT scan), with the timing of joining depending on what blood-thinning medication was taken after the stroke - People who have had a TIA (mini-stroke) lasting 10 minutes or more, with symptoms such as weakness, s...

Who might be able to join this trial: - People who have weakness or paralysis on one side of the body only, with significant loss of movement in the affected arm. - People who are able to understand and agree to take part in the trial on their own behalf. Who may not be able to join: - People who have problems with mu...

Who might be able to join this trial: - People who have had their first-ever stroke at least 3 months ago - People aged between 20 and 80 years old - People with a moderate level of arm and hand movement difficulty, as measured by a specific arm function score (confirm with trial site for exact score range) - People wh...

Who might be able to join this trial: - It has been at least 6 months since the person had a stroke - The person is able to make certain minimum hand and wrist movements: bending the wrist upward at least 20 degrees from a fully bent position, moving the thumb outward or upward at least 10 degrees, and straightening ea...

**Who might be able to join this trial:** - You have been diagnosed with Multiple Sclerosis, Parkinson's Disease, Stroke, or an acquired brain injury - You are able to attend at least 10 sessions with the robotic system used in this trial - You are able to attend sessions at least twice a week - You are 18 years of age...

**Who might be able to join this trial:** - You are 40 years of age or older and have recently had a stroke or a "mini-stroke" (also called a TIA, or transient ischemic attack) - Your stroke has been confirmed by a doctor using brain scans, such as a CT scan or an MRI scan - Your stroke was caused by something other th...

**Who might be able to join this trial:** - People who have been diagnosed with a sudden, non-trauma-related bleed in the brain, confirmed by a CT scan (without contrast dye). - People where the brain imaging procedure (called a cerebral DSA, a detailed X-ray of blood vessels) can be started within 3 hours of symptoms...

Who might be able to join this trial: - People who are willing and able to give their consent to take part in the study - People aged 18 years or older - People who have been clinically diagnosed with a stroke that has affected their arm or hand, and who have enough movement in that arm or hand to complete a motor lear...

Who might be able to join this trial: - People who have had a stroke at least 6 months ago - People who can move their more-affected arm to a minimum level: able to raise the shoulder at least 30 degrees forward or out to the side, able to start bending and straightening the elbow, and able to start moving the wrist, f...

**Who might be able to join this trial:** *For stroke patients:* - People who were sent home from NINSH hospital after a stroke, or who visited NINSH shortly after having a stroke - People who are having their first-ever stroke (not a repeat stroke) - People who have had any type of stroke, except a specific type call...

Who might be able to join this trial: - A medical team has decided that the person needs a procedure to remove a blood clot as part of stroke treatment, following their hospital's guidelines. - The person is 18 years of age or older, of any sex. - The person has a stroke severity score of 4 or higher on a standard medi...

Who might be able to join this trial: - People who have been admitted to hospital with a blockage in a large blood vessel in the brain and are being treated with a device called the Tigertriever, according to its approved instructions for use. - People for whom the Tigertriever was used as the first treatment attempted...

**Who might be able to join this trial:** - People who have had a stroke or a temporary stroke-like episode (called a TIA) that was caused by a narrowed artery inside the brain. A TIA is defined here as a sudden episode of neurological symptoms — such as weakness, difficulty speaking, temporary vision loss in one eye,...

**Who might be able to join this trial:** - People who have had their first-ever ischemic stroke (a stroke caused by a blocked blood vessel) and are either more than 3 months or more than 6 months into recovery - People who still have lasting movement or motor difficulties in one or both arms following their stroke - P...

"Who might be able to join this trial: - People who are 18 years of age or older - People who have a family member or loved one with CADASIL (a rare inherited condition affecting blood vessels in the brain), or who may be at risk of having CADASIL themselves Who may not be able to join: - People who are under 18 years...

**Who might be able to join this trial:** **For stroke survivors:** - Adults aged 20 years or older - People who have been diagnosed with their first stroke within the past two years - People who speak Mandarin - People who have an identified main family caregiver who helps look after them and takes responsibility for...

Who might be able to join this trial: - People who are 18 years of age or older. - People who have had an ischemic stroke (a stroke caused by a blocked blood vessel in the brain) where a blockage is suspected in one of several major blood vessels in the brain or neck — specifically the internal carotid artery, certain...

Who might be able to join this trial: - People who have had their first-ever stroke - People whose stroke happened more than six weeks ago - People who are having difficulty swallowing as a result of their stroke - People with good enough comprehension, as measured by a standard language test (a score not below PT 53 o...

**Who might be able to join this trial:** - People who have had a single ischemic stroke (a stroke caused by a blocked blood vessel) that was confirmed by brain imaging and resulted in weakness or partial paralysis on one side of the body - People who are at least six months past their stroke - People whose arm and ha...

Who might be able to join this trial: - People scheduled for planned (non-urgent) heart surgery involving coronary artery bypass grafting and/or heart valve surgery and/or surgery on the upper part of the main artery from the heart (the ascending aorta), whether for the first time or as a repeat procedure, where a hear...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing the consent form - People who had a stroke caused by a blockage in the brain (not a bleed) between 1 and 14 days ago, confirmed by a brain scan (MRI or CT) - People who are willing and able to sign a consent form...

Who might be able to join this trial: - Adults who are 18 years of age or older - People who have been admitted to Lynn Rehabilitation Center with a recent ischemic stroke (a stroke caused by a blocked blood vessel) diagnosed within the past month - People who are able to give written consent to participate, or who hav...

**Who might be able to join this trial:** - People aged 18 or older - People who received a clot-dissolving drug called tenecteplase through a drip for a stroke, and whose symptoms either stayed about the same, got worse, or fluctuated up and down significantly within 4 to 24 hours after that treatment - People whose...

Who might be able to join this trial: - People who have had a stroke on one side of the brain only, either caused by a blocked blood vessel or a bleed in the brain - People whose stroke happened within the last 3 months - People who have significant weakness in the arm on the affected side (muscle strength rated at 3 o...

Who might be able to join this trial: - People who are suspected of having had a stroke or reduced blood flow to the brain and need brain and blood vessel scans (such as CT or MRI) - People with no history of kidney failure - People aged 18 years or older - People who have given written consent to participate Who may...

Who might be able to join this trial: - People who are between 50 and 80 years old - People who have had a single stroke at least 6 months ago - People who have full movement control in their unaffected arm, and at least some ability to lift the affected shoulder against gravity Who may not be able to join: - People w...

Who might be able to join this trial: - People who are 18 years of age or older - People who are covered by social security - Women of childbearing age who are using an effective form of contraception - People who have provided written consent to participate Who may not be able to join: - People who have any medical r...

**Who might be able to join this trial:** - People who have had one stroke, on one side of the brain only, that occurred between 2 and 18 months before joining the trial - People whose hand has mild to moderate impairment after their stroke, based on a specific hand function rating scale called the Chedoke-McMaster Str...

Who might be able to join this trial: - People who are 18 years of age or older, or who have reached the legal age to give consent in their region - People (or their legal representative, where required) who have agreed to allow their data to be used in the trial Who may not be able to join: - People whose brain scan...

Who might be able to join this trial: - Adults aged 18 or older who have given their consent (or had consent given on their behalf) to participate. - People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) with noticeable neurological effects, such as problems with speech, movement, thi...

**Who might be able to join this trial:** - People who have had their first-ever stroke, where more than 12 months have passed since it occurred - People with mild to moderate weakness or movement difficulty in the upper arm and hand, based on a specific movement assessment score (between 15 and 53 on the Fugl-Meyer Up...

Who might be able to join this trial: **Initial enrolment (after a possible mini-stroke/TIA):** - People who have been assessed by a stroke specialist doctor for a possible mini-stroke (TIA), whether or not a firm diagnosis has been made - People who have been prescribed blood-thinning medication (such as antiplatelet...

Who might be able to join this trial: - People aged 18 years or older - People who have been diagnosed with a stroke (either a blockage-type or bleeding-type stroke), confirmed by medical imaging - People who have been assessed by a heart specialist and cleared to take part in a cardiac rehabilitation program, with no...

Who might be able to join this trial: - You must be 18 years of age or older - You must have had your first-ever stroke (specifically an ischemic stroke affecting the front part of the brain), confirmed by a routine MRI scan - You must be enrolled within 10 days of when your stroke happened Who may not be able to join...

Who might be able to join this trial: - People who have been diagnosed with aphasia (difficulty with language and communication) lasting more than 6 months, caused by a stroke that affected the left side of the brain. - People whose results on a specific language assessment test (the Comprehensive Aphasia Test) show di...

Who might be able to join this trial: - You were admitted to the hospital between January 1st, 2018 and January 1st, 2028 - You are 18 years old or older - You have been diagnosed with an ischemic stroke (a stroke caused by a blocked blood vessel), confirmed by a brain scan (CT or MRI) - A scan (CTA or MRA) has shown a...

**Who might be able to join this trial:** - Adults between 18 and 75 years old - People who are currently hospitalised in the surgical intensive care unit at Lariboisière Hospital after a brain bleed (subarachnoid haemorrhage) caused by a ruptured aneurysm - People whose condition falls within a specific range of sever...

Who might be able to join this trial: - You are between 18 and 85 years old - You have been diagnosed with an acute ischemic stroke (a stroke caused by a blood clot) and are a candidate for clot-dissolving treatment - You are planned to receive, or have already received, a clot-dissolving medication called "non-immunog...

Who might be able to join this trial: - People who are older than 18 years of age - People who have developed difficulty with language or communication (aphasia) after a stroke - People who have developed a condition after a stroke where they have trouble paying attention to one side of their body or environment (negle...

Who might be able to join this trial: - People who have been admitted to Sahlgrenska University Hospital in Gothenburg, Sweden with their first-ever ischemic stroke (caused by a blockage in a blood vessel in the brain) or their first-ever intracerebral haemorrhage (caused by bleeding inside the brain) Who may not be a...

**Who might be able to join this trial:** - People who have been diagnosed with an ischemic stroke (a stroke caused by a blockage) for the first time, following Chinese national stroke diagnosis guidelines from 2018 - People whose condition is currently stable after their first stroke - People whose internal carotid a...

**Who might be able to join this trial:** - People who had a stroke between 1 and 6 months ago - People who have weakness on one side of their body (but not due to problems with the cerebellum, a part of the brain that controls balance and coordination) - People who are able to walk at least 10 meters (with or without...

Who might be able to join this trial: - People who have had an ischemic stroke (a stroke caused by a blocked blood vessel) as defined by the American Heart Association. - People whose CT or MRI scan shows the stroke affected the front part of the brain (frontal, parietal, or upper temporal lobes), OR whose brain artery...

Who might be able to join this trial: - People who are at least 21 years old - People who had a stroke at least 6 months before joining the study - People whose balance score on a standard test called the Berg Balance Scale is below 52 (a lower score indicates more difficulty with balance) - People who are able to stan...

Who might be able to join this trial: - People who have a narrowing of the carotid artery (a major blood vessel in the neck) that is causing symptoms, along with evidence of a stroke on the same side as the narrowing - People who have at least 1mm of soft (non-hardened) plaque buildup on the same side of the neck as th...

**Who might be able to join this trial:** - Adults between 18 and 60 years of age. - People who are able to understand the purpose of the trial and are willing to participate and sign a consent form. - People who have been confirmed to have a patent foramen ovale (a small opening between the upper chambers of the hear...

Who might be able to join this trial: - You have read and signed an agreement (consent form) saying you agree to take part in the study - You are 45 years old or older Who may not be able to join: - You do not wish to take part in the study - You have had heart muscle damage or a heart attack within the last two weeks...

**Who might be able to join this trial:** - People aged between 40 and 85 years old - People whose native language is French - People who are affiliated with the French Social Security system - People who have been assessed at a University Memory Clinic and have a mild or major memory or thinking disorder linked to Alz...

Who might be able to join this trial: - People who have had a stroke - People who have one or more risk factors for stroke, such as high blood pressure, diabetes, HIV, malaria, physical inactivity, or obesity Who may not be able to join: - People who have not had a stroke and also have no known risk factors for stroke...

Who might be able to join this trial: - You are male or female and older than 18 years of age - You had a stroke (either a bleed in the brain or a blockage) more than 3 months ago, confirmed by a brain scan (CT or MRI) - You experience severe fatigue, shown by an average score of more than 4 on a fatigue rating scale -...

Who might be able to join this trial: - People who have been diagnosed with Mild Cognitive Impairment, Parkinson's disease, or stroke - People who have functional use of at least one hand - People who have normal vision, or vision that is corrected to normal (for example, with glasses or contact lenses) Who may not be...

Who might be able to join this trial: - Adults (aged 18 or older) who have weakness or limited movement on one side of the body as a result of a stroke. - The stroke must have occurred at least 6 months ago. - Scores on a specific arm movement test called the Fugl-Meyer Upper Extremity scale must fall within a particul...

**Who might be able to join this trial:** - People aged 18 or older (there is no upper age limit) - People showing signs consistent with an acute ischemic stroke (a stroke caused by a blood clot blocking blood flow to the brain) - People with a stroke severity score above 5 at the time of enrolment, where the last tim...

Who might be able to join this trial: - Adults aged 18 or older who have had a non-traumatic brain bleed (bleeding inside the brain not caused by an injury) and who arrived for treatment within 4.5 hours of their symptoms starting. Who may not be able to join: - People whose brain bleed was caused by blood thinning me...

**Who might be able to join this trial:** - People aged between 22 and 85 years old - People who speak English (Spanish-only speakers may be included at some trial sites in the future) - People who have been diagnosed with atrial fibrillation (an irregular heartbeat) that is not permanent - People whose stroke risk sc...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who have had a carotid artery ultrasound or other imaging that showed a narrowing of 60% or more in a carotid artery (the arteries in the neck that supply blood to the brain), but who have no symptoms from this narrowing - People whose s...

**Who might be able to join this trial:** - People who are over 18 years of age - People who have had an ischemic stroke (a stroke caused by a blocked blood vessel) - People who were admitted to hospital within 90 days of their stroke **Who may not be able to join:** - People who have had a hemorrhagic stroke (a strok...

Who might be able to join this trial: - People who are 18 years of age or older - People who were proficient in English before their stroke - People who have had a stroke on the left side of the brain (either a blocked blood vessel or a bleed), confirmed by a brain scan, where the stroke happened either between 1 and 4...

**Who might be able to join this trial:** - You are 18 years old or older - You are currently a patient receiving inpatient rehabilitation at St. John's Rehab - You had a stroke within the past two months before joining the study - You have been identified as being at possible risk for depression and/or anxiety based o...

**Who might be able to join this trial:** - People who are already enrolled in the main EXPLO-CCE study - People who are completing at least 2 aerobic exercise sessions per week (either as a new routine or continuing a previous one) - People who experienced exercise-related heat stroke at least 2 months ago **Who may...

Who might be able to join this trial: - People aged 18 to 79 years old - People who have signs of an acute ischemic (non-bleeding) stroke with a stroke severity score of 6 or higher on a standard medical scale - People whose brain CT scan shows an ASPECTS score of 6, which is a measure of how much brain tissue appears...

**Who might be able to join this trial:** **For patients:** - You have had a stroke on the right side of the brain (your first stroke), confirmed by a brain scan, and it happened less than 1 year ago - You are right-handed - You are 18 years of age or older - French is your first/native language - You are covered by a...

**Who might be able to join this trial:** - Adults between 35 and 70 years old who have been diagnosed with a stroke affecting a specific area of the brain (the middle cerebral artery territory), confirmed by clinical assessment and brain imaging - People who have weakness or partial paralysis on one side of the body...

Who might be able to join this trial: - People who have had a cerebral stroke and are over 20 years old - People who have muscle stiffness (spasticity) in the foot/ankle muscles that point the foot downward, rated above 1 on a standard medical scale called the Modified Ashworth Scale - People whose basic body signs (su...

**Who might be able to join this trial:** - You must be over 18 years old - You have had a stroke that has been confirmed by a doctor (for patients joining the study) - You are able to focus and concentrate for at least 15 minutes at a time to complete some thinking and memory tests **Who may not be able to join:** -...

**Who might be able to join this trial:** - You have had a stroke (either a bleed in the brain or a blockage) that has caused weakness on one side of your body - Your stroke happened either less than 6 months ago (recent/subacute) or more than 6 months ago (long-term/chronic) - You are between 18 and 75 years old - You...

Who might be able to join this trial: - People aged between 18 and 80 years old - People who have been diagnosed with a brain bleed (haemorrhage) in a specific area of the brain called the basal ganglia, confirmed by a CT scan - People whose brain bleed is between 20 and 40 millilitres in size, with less than 3mm of sh...

Who might be able to join this trial: - Adults aged 18 or older - People admitted to an intensive care unit (ICU) due to a sudden, serious brain injury - People whose brain injury has been confirmed by a CT scan and/or MRI scan - People for whom a contrast ultrasound scan (a special type of imaging using a contrast age...

**Who might be able to join this trial:** - People aged 40 years or older - People whose stroke began within the past 2 weeks - People whose stroke severity score (a standardised medical rating scale called the NIHSS) was 16 or below at the start - People whose stroke has been confirmed as an ischemic stroke (caused b...

Who might be able to join this trial: - People who are between 18 and 64 years old - People who have been clinically diagnosed with a first or repeat stroke (either ischaemic, caused by a blocked blood vessel, or haemorrhagic, caused by bleeding in the brain) - People who are living at home at the time of the study - P...

Who might be able to join this trial: - People who are 18 years of age or older - People who have weakness on one side of the body following a first stroke that occurred more than 1 year ago - People whose affected arm has enough movement to reach out to about 90% of the distance between their hand and shoulder - Peopl...

Who might be able to join this trial: **Phase 1 (System Design & Feasibility Study)** - People who have had a stroke on one side of the brain only - People between 20 and 80 years old - People whose arm movement after stroke falls within a specific range, as measured by a standard assessment called the Fugl-Meyer Uppe...

**Who might be able to join this trial:** - People who have had an acute stroke caused by a blocked blood vessel in the back part of the brain (posterior circulation), confirmed by symptoms and brain scans. - People whose stroke is caused by a blockage in a specific artery at the base of the brain (called the basilar...

Who might be able to join this trial: - People who have been admitted to a participating hospital with sudden stroke symptoms, within 24 hours of those symptoms starting Who may not be able to join: - People who would not be available for follow-up check-ins after the initial visit (for example, people who do not live...

Who might be able to join this trial: - People who have had a brain injury, stroke, or spinal cord injury, and whose overall medical condition has become stable. - People who have had an ultrasound scan of their blood vessels that shows no blood clots in the deep veins (a condition called deep vein thrombosis). - Peopl...

Who might be able to join this trial: - People who are already enrolled in the CAPTIVA trial, which involves having had a mild stroke caused by a significant narrowing (70–99%) of a specific artery in the brain, within the last 30 days - People who are able to have a baseline MRI scan done within 14 days of joining the...

**Who might be able to join this trial:** - You are 18 years of age or older - You had some level of physical disability before your stroke (needing help with some daily activities), and this had been the case for at least 3 months before your stroke - You arrived at the study hospital within 24 hours of when you were...

Who might be able to join this trial: - You have had a stroke on one side of the brain (either due to a blocked blood vessel or bleeding in the brain) - Your stroke happened within the last 3 months - You have significant weakness in your arm or hand (scoring 3 or below on a standard muscle strength test) - You have no...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with heat stroke - People who have given informed consent, or whose family members have given consent on their behalf Who may not be able to join: - People who need immediate cardiopulmonary resuscitation (...

**Who might be able to join this trial:** - Adults between 18 and 65 years old - People who have had a brain bleed (cerebral hemorrhage) and, after surgery, have been in a state of reduced consciousness for more than 28 days - People whose level of consciousness, as measured by a standardised assessment tool called the...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with heat stroke - People whose informed consent, or the consent of a family member, has been obtained Who may not be able to join: - People who require immediate cardiopulmonary resuscitation (emergency ch...

**Who might be able to join this trial:** - People aged 18 years or older - People who are suspected to have had an acute ischemic stroke affecting the front part of the brain - People with a stroke severity score of 4 or higher on a standard medical scale before being enrolled (if the score is 4–5, the stroke must be...

**Who might be able to join this trial:** - Adults between 18 and 78 years old (who have not yet turned 79) - People, or their legal representative, who are willing to give consent before any study procedures begin - People who have had an ischemic stroke (caused by a blockage, not bleeding) that has been confirmed by...

**Who might be able to join this trial:** - People aged between 35 and 75 years old (inclusive). - People who have been diagnosed with either an ischemic stroke (a blockage-type stroke) or a hemorrhagic stroke (a bleeding-type stroke), where the stroke affected the left side of the brain, and where the stroke occurred...

**Who might be able to join this trial:** - People aged between 35 and 75 years old (inclusive) - People who have been diagnosed with either an ischemic stroke (caused by a blockage) or a hemorrhagic stroke (caused by bleeding), where the stroke affected the left side of the brain, and the stroke occurred between 15 d...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People who have been diagnosed with an ischemic stroke (a stroke caused by a blood clot) within the past two months, including specific types such as lacunar, large-vessel, or cardioembolic strokes - People whose stroke occurred alongs...

**Who might be able to join this trial:** - People who have persistent or permanent atrial fibrillation (an irregular heartbeat that does not return to normal on its own), or people who have occasional episodes of atrial fibrillation and have previously had a stroke or blood clot travelling to another part of the body...

Who might be able to join this trial: - People aged between 35 and 75 years old (including those who are exactly 35 or 75). - People who have been diagnosed with either an ischemic stroke (caused by a blocked blood vessel) or a hemorrhagic stroke (caused by bleeding in the brain), where the affected area is on the left...

**Who might be able to join this trial:** - You are 18 years of age or older - You are willing and able to sign a consent form agreeing to take part - You have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF) — either all the time, most of the time, or coming and going — whether known...

Who might be able to join this trial: - People who have been diagnosed with atrial fibrillation (an irregular heartbeat), whether or not it is related to a heart valve problem. - People whose atrial fibrillation has been confirmed by a heart rhythm recording, such as a standard ECG, a rhythm strip, an event monitor, a...

Who might be able to join this trial: - People who have been clinically diagnosed with a stroke (either an ischemic stroke, which is caused by a blocked blood vessel, or an intracerebral haemorrhage, which is caused by bleeding in the brain). - People who are within 6 weeks of their confirmed stroke. Who may not be ab...

Who might be able to join this trial: - People who have had their first stroke affecting the right side of the brain, and who are over 18 years of age - People who are between 1 and 4 months since being diagnosed with a right brain stroke - People who are able to sit up, see out of both eyes with vision of at least 20/...

**Who might be able to join this trial:** - People who have had their first stroke on one side of the brain, where the stroke occurred at least 3 months ago but no more than 3 years ago - People between 30 and 80 years of age - People whose affected arm has some remaining movement, as measured by a standard arm functi...

**Who might be able to join this trial:** - The person is willing to give written consent to participate and is able to move around freely, without conditions affecting the bones, joints, or brain that would prevent them from travelling to appointments independently. - The person lives in the same city or suburb where...

**Who might be able to join this trial:** - People aged between 35 and 75 years old (including those who are exactly 35 or 75). - People who have been diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel) affecting the left side of the brain, where the stroke occurred at least 15 days ago...

**Who might be able to join this trial:** - People aged 18 years or older - People whose stroke severity score (called NIHSS) is 4 or higher, indicating a moderate to severe stroke - People whose brain imaging (using CTA, MRA, or DSA scans) has confirmed a blockage in a large artery in the brain - People whose brain sc...

Who might be able to join this trial: - You have had your first stroke at least 6 months ago - You score 24 or higher on a standard memory and thinking test called the Mini-Mental State Examination - The stiffness or tightness in your ankle muscles is mild to moderate (confirmed by a medical assessment scale) - You are...

**Who might be able to join this trial:** - People between the ages of 30 and 80 years old - People with a significant narrowing (70%–99%) of certain brain arteries, confirmed by a specialised X-ray procedure called DSA, that is causing symptoms - People who have had a mild stroke (with a low symptom severity score) w...

Who might be able to join this trial: - People who are over 18 years old - People who are able to understand and voluntarily sign a consent form before the treatment begins - People who have been medically diagnosed with a stroke (either ischemic, caused by a blocked blood vessel, or hemorrhagic, caused by bleeding in...

Who might be able to join this trial: - People who are 60 years of age or older. - People who are planning to have a new or repeat open-heart surgery involving the aortic valve, mitral valve, or multiple heart valves, with or without coronary bypass surgery (certain specific combinations apply — confirm with trial site...

Who might be able to join this trial: - People aged between 18 and 75 years old - People who had a stroke at least 6 months ago and whose condition is now medically stable - People who had a stroke on one side of the brain only, with just one stroke event (any type — whether caused by a blockage or bleeding — and any s...

**Who might be able to join this trial:** - People aged between 18 and 80 years old - People who have been diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel) and have a stroke severity score of 6 or higher on a standard medical scale called the NIHSS - People who can begin treatment wi...

Who might be able to join this trial: - People who are 18 years of age or older - People who are scheduled to have a HeartMate 3 durable Left Ventricular Assist Device (a mechanical heart pump) implanted Who may not be able to join: - People who are under 18 years of age - People who are scheduled to receive a durable...

Who might be able to join this trial: - People aged 18 or older - People who have been clinically diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel) and received a standard dose of a clot-busting medication called tenecteplase by IV drip within 4.5 hours of their stroke starting - Peopl...

Who might be able to join this trial: - People who have developed a sudden, specific neurological problem (such as weakness, speech difficulty, or vision changes) within the last 24 hours, with at least a minimal level of severity as measured by a standard stroke assessment tool Who may not be able to join: - People w...

Who might be able to join this trial: - People who have been diagnosed with a stroke affecting the left side of the brain, which has caused difficulty with language (aphasia). - People who are enrolling at least one month after their stroke occurred. - People who were fluent in English before their stroke. - People who...

**Who might be able to join this trial:** - People who have given written consent to participate, or whose legal representative has done so on their behalf. - People aged 18 years or older and under 85 years old. - People who have had a stroke caused by a blockage in a large blood vessel, who underwent a mechanical cl...

Who might be able to join this trial: - People who have weakness on one side of their body following their first stroke (either a blocked or bleeding blood vessel in the brain) - People who are in the early recovery period, between 15 days and 6 months after their stroke - People aged between 35 and 75 years old - Peop...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have weakness or reduced movement in their upper arm following a stroke on one side of the body, confirmed by an MRI or CT scan - People who are between two weeks and six months past the date of their stroke - People whose...

**Who might be able to join this trial:** - People aged between 18 and 90 years old (male or female) - People who have had a stroke recently — specifically, those who can be enrolled within 12 weeks of the stroke happening - People who were largely independent before their stroke (with little or no disability beforehan...

Who might be able to join this trial: - People aged 20 or older - People who have been diagnosed with a stroke - People whose stroke occurred at least 6 months ago - People whose affected arm has a moderate level of movement and muscle control, rated at stage III, IV, or V on a scale called the Brunnstrom scale (confir...

**Who might be able to join this trial:** - People aged 18 or older who are able to give their own consent to participate - People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation or atrial flutter (which comes and goes, is ongoing, or is permanent) and who are not caused by a hear...

Who might be able to join this trial: - People who are older than 18 years of age - People who have spastic weakness on one side of the body (left or right) following a single stroke (either a bleed in the brain or a blocked blood vessel), where the stroke occurred more than 6 months ago - People who are able to walk c...

Who might be able to join this trial: - People who have long-term muscle stiffness or spasms (spasticity) that have not improved with standard treatments, or where standard treatments cannot be used, and where the problem is linked to one or more nerves in the spine. - People aged 16 or older (if under 18, a parent or...

**Who might be able to join this trial:** - People aged 50 years or older - People of Asian ethnicity - People who have been newly diagnosed with one of these conditions: stroke, traumatic brain injury (a brain injury caused by a physical impact), knee osteoarthritis (wear-and-tear joint disease in the knee), or breas...

Who might be able to join this trial: - You must be at least 18 years old. - You must have had a heart procedure to close off a small pouch in the heart (called the left atrial appendage) using a specific device (either a Watchman, Watchman FLX, or Amplatzer Amulet) at the trial's hospital between January 2019 and June...

**Who might be able to join this trial:** - People aged 21 to 85 years, both male and female - People who have had their first-ever stroke (either a blocked blood vessel or a bleed in the brain), confirmed by a specialist doctor or brain scan - People who are more than 16 weeks past their stroke - People whose stroke...

**Who might be able to join this trial:** - People who are at least 18 years old - People who have had a stroke on one side of the brain at least 3 months before joining the trial - People who score an average of 4 or higher on a fatigue rating scale called the Fatigue Severity Scale (FSS) - People who have some abilit...

Who might be able to join this trial: - People who have had a recent heart attack (such as a STEMI or NSTEMI) within the past 30 to 120 days, or a mini-stroke or stroke caused by a blockage in a nearby large blood vessel, confirmed by ultrasound, CT, or MRI scan - People whose symptoms are stable and whose body is copi...

**Who might be able to join this trial:** - People between 18 and 65 years of age, of any gender - People who have had their first bleeding episode from a brainstem cavernous malformation (a small, abnormal cluster of blood vessels in the brainstem) within the six months before joining the trial - People whose brainste...

**Who might be able to join this trial:** - Adults between 18 and 80 years of age. - People who have recently experienced a head injury that also involved at least one other part of the body being injured, OR people who have had a stroke or bleeding in the brain with no signs of lung infection caused by inhaling fluid...

Who might be able to join this trial: - People admitted to the participating hospital between June 1st, 2019 and January 1st, 2029 - People who have recently had an acute ischemic stroke (a stroke caused by a blocked blood vessel in the brain) - People whose stroke symptoms were present at the time of hospital admissio...

**Who might be able to join this trial:** - People aged 40 years or older - People who have 3 or more of the following stroke risk factors: high blood pressure, high cholesterol, diabetes, irregular heartbeat or heart valve disease, a history of smoking, being significantly overweight or obese, low levels of physical a...

**Who might be able to join this trial:** - A signed consent form has been provided by the patient or, if the patient is unable to consent, by their next of kin - People aged 18 years or older - People who had an ischemic stroke (a stroke caused by a blocked blood vessel) with symptoms starting within 48 hours before...

**Who might be able to join this trial:** - You are over 18 years old - You have had your first stroke that caused a significant physical disability - You have weakness or partial paralysis on one side of your body (due to stroke) and are between 1 and 4 months from when the stroke happened - You have significant diffi...

**Who might be able to join this trial:** - You must already be taking a stable, established dose of recommended medications for Heart Failure. - You must have an existing diagnosis of Heart Failure, confirmed by a scan or imaging test within the last 6 months. - You must be between 18 and 80 years old. - Your Body Ma...

Who might be able to join this trial: - People who have had a single stroke event that was confirmed by an MRI or CT scan - People aged between 18 and 85 years old - People whose stroke occurred within the last six months - People whose score on a standard memory and thinking test (called the Montreal Cognitive Assessm...

**Who might be able to join this trial:** - People who have had their first-ever stroke between 2 weeks and 2 years ago, which has left one side of the body weakened or paralysed. - People who are able to understand and follow simple instructions. - People who can sit upright and maintain their balance while seated. -...

Who might be able to join this trial: - People who have been clinically diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel in the brain) - People whose stroke symptoms began within the last 9 hours - People who have a blockage in one of the major or medium-sized blood vessels in the brai...

Who might be able to join this trial: - You have been diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel) affecting a large or medium-sized blood vessel in the brain, as confirmed by a doctor following Chinese stroke diagnosis guidelines. - You, or someone legally authorized to make deci...

**Who might be able to join this trial:** - People between 18 and 90 years of age - People who have weakness on one side of the body following a stroke - People whose stroke occurred more than 6 months ago - People who are able to walk on a treadmill for at least 2 minutes, with or without an ankle-foot brace - People...

**Who might be able to join this trial:** - People aged 18 years or older - People who had a stroke caused by a blocked blood vessel, with symptoms starting within the last 4 weeks - People whose stroke has been rated as "moderate to severe" using a standard medical stroke scale (a score of 6–24 on the NIHSS) at the ti...

Who might be able to join this trial: - People of any gender who have had either a stroke caused by a blocked blood vessel or a stroke caused by bleeding in the brain - The stroke must have occurred between 7 and 14 days before joining the trial - People who were living independently and managing daily life on their ow...

**Who might be able to join this trial:** - People aged 18 or older - People who are currently hospitalised after having an ischemic stroke (a stroke caused by a blocked blood vessel) in a specific deep region of the brain supplied by the middle cerebral artery - People whose stroke can be seen on an MRI scan - People...

**Who might be able to join this trial:** - People aged 18 or older - People experiencing symptoms of an acute ischemic stroke (a stroke caused by a blocked blood vessel) - People whose imaging (CTA or MRA scan) has confirmed a blockage in a specific artery supplying the front part of the brain (the intracranial carot...

**Who might be able to join this trial:** - People who have had an ischemic stroke (a stroke caused by a blocked blood vessel in the brain) - People whose stroke occurred no less than 2 months ago and no more than 6 months ago - People whose stroke recovery falls within a specific range on a medical scale called the TI...

**Who might be able to join this trial:** - You are 18 years of age or older - You have had symptoms of an acute ischemic stroke (a stroke caused by a blockage) and your initial stroke severity score was below 6 points - Your symptoms got worse within 7 days of your stroke first starting - You can be enrolled in the s...

**Who might be able to join this trial:** - People who have had a stroke, mini-stroke (TIA), or a blood clot in another organ or body system that is linked to a hole in the heart called a patent foramen ovale (PFO) - People whose heart has been confirmed by ultrasound to have this hole (PFO) present - People aged 18 or...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with an acute ischemic stroke (a stroke caused by a blood clot blocking blood flow to the brain) - People who are within 6 hours of when their stroke symptoms started - People who have already received, or are planned t...

**Who might be able to join this trial:** - People who have had a stroke within the last year - People who have some ability to walk, either with help or more independently, based on a walking ability assessment scale (scored 2–5 on the Functional Ambulation Classification) **Who may not be able to join:** - People wh...

**Who might be able to join this trial:** - People who are male or female and aged between 18 and 79 years old - People who have had an ischemic stroke (caused by a blockage), a hemorrhagic stroke (caused by bleeding in the brain), or a Transient Ischemic Attack (a brief, temporary stroke-like episode with a severity...

**Who might be able to join this trial:** - You are 16 years of age or older and have had a sudden, serious brain or nervous system injury - You need a breathing machine (ventilator) to help you breathe due to a neurological condition - Your lungs are otherwise healthy, meaning your chest X-ray looks normal and your bl...

**Who might be able to join this trial:** - You are an adult currently admitted to Cimiez University Hospital - You have had a stroke (either a blockage or a bleed in the brain) within the last two weeks - You have weakness on one side of your body that requires rehabilitation treatment - You have scored 6 or below on...

Who might be able to join this trial: - Adults aged 18 or older. - People who have been clinically diagnosed with an acute ischemic stroke (a stroke caused by a blockage in blood flow to the brain), confirmed by brain imaging showing a relevant area of damage, or with symptoms lasting more than 24 hours, with a scan ru...

Who might be able to join this trial: - People who were admitted to hospital between January 1, 2018 and January 1, 2028 - People who arrived at the hospital more than 24 hours after the last time they were known to be well - People whose ischemic stroke (a stroke caused by a blocked blood vessel) was confirmed by a CT...

Who might be able to join this trial: - People who are 20 years of age or older - People who have weakness or reduced movement on one side of the upper body (arm, shoulder, or hand) caused by their first-ever stroke - People who have some ability to move the affected arm or hand voluntarily - People who are able to fol...

Who might be able to join this trial: - People who are 18 years of age or older - People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) within 24 hours of when they were last known to be well - People (or their representative) who are able to sign a written consent form before joining...

**Who might be able to join this trial:** - People who have had a recent stroke affecting the front part of the brain and are receiving a procedure to open a blocked blood vessel within 24 hours (without prior clot-busting medication). - People who are 18 years of age or older. - People who had little to no disability...

**Who might be able to join this trial:** - You had an ischemic stroke (a stroke caused by a blood clot) between 2 and 12 weeks before joining the study, confirmed by a brain scan (CT or MRI), and your stroke symptoms lasted more than 24 hours - Your stroke caused mild to moderate physical or movement difficulties (no...

Who might be able to join this trial: - People who were fluent and able to read in English before their stroke - People who have had their first-ever stroke - People who are more than 3 months past their stroke - People who have difficulty reading after their stroke, based on specific accuracy scores for reading words...

Who might be able to join this trial: **For people who have had a stroke:** - People between 20 and 79 years old - People who score 26 or higher on a standard memory and thinking test called the Montreal Cognitive Assessment - People who have had a stroke affecting one side of the body, either from bleeding in the bra...

Who might be able to join this trial: - People aged 18 or older - People who have had an ischemic stroke (the type caused by a blocked blood vessel, not a bleed) - People who are between 3 weeks and 60 months (5 years) past their stroke - People whose arm function falls within a specific range on a test called the Acti...

Who might be able to join this trial: - People who have had their first ischemic stroke (a stroke caused by a blocked blood vessel, not bleeding) within the past 3 months, confirmed by a CT scan or MRI. - People who have enough mental clarity to understand the study procedures and agree to take part. Who may not be ab...

**Who might be able to join this trial:** *For Aim 1:* - Adults aged 18–23 who are neurotypical (no neurological conditions) and right-handed *For Aim 2 – neurotypical participants:* - Neurotypical people of a similar age to the stroke participants in the study - People with no musculoskeletal (bone, joint, or muscle...

**Who might be able to join this trial:** - People who have had a stroke (either caused by a blocked blood vessel or bleeding in the brain), in any part of the brain, that occurred at least 24 hours before joining the study - People who are willing and able to give their consent to take part in the study - People whose...

**Who might be able to join this trial:** - People who are at least 3 months past having a stroke - People aged 18 or older - People who have been prescribed a leg brace (called an AFO) or who a doctor has identified as a possible candidate for one - People who are able to walk at least 10 metres, with or without a wa...

Who might be able to join this trial: - You have had a stroke and are 18 years of age or older Who may not be able to join: - You have another condition affecting the brain or nervous system (such as Parkinson's disease or Multiple Sclerosis) that affects your ability to move or balance, in addition to your stroke - Y...

Who might be able to join this trial: - People aged between 18 and 45 years old. - People who have been diagnosed with an ischemic stroke (a stroke caused by a blocked blood vessel) confirmed by a brain MRI scan, whether or not a major blood vessel was blocked, in any part of the brain. - People who speak and read Fren...

Who might be able to join this trial: - People who are 18 years of age or older - People who have had their first-ever stroke (either a blocked blood vessel or a bleed in the brain) affecting one side of the brain or the brainstem - People who have weakness in one arm as a result of the stroke, within a specific range...

**Who might be able to join this trial:** - People aged 30 to 85 years at the time of signing consent - People who have weakness on one side of the body caused by one or more strokes (either a blocked blood vessel or a bleed in the brain) - People whose most recent stroke (for which they received treatment) happened a...

**Who might be able to join this trial:** - You have had a stroke that caused weakness or paralysis on one side of your body, and it happened between 7 days and 3 months ago, and you are currently in the hospital - Your affected arm and hand have limited movement, based on a specific stroke recovery score (confirm with...

**Who might be able to join this trial:** - People who have had a stroke (either a blocked blood vessel or a bleed in the brain) that was confirmed by doctors using brain scans such as a CT or MRI. - People aged between 21 and 90 years old, of any gender. - People who are at least 28 days past their stroke. - People w...

**Who might be able to join this trial:** - People who have had a stroke caused by either a blocked blood vessel or bleeding in the brain - People who are between 6 and 24 months past their stroke - People who have finished their early post-stroke rehabilitation program (the intensive rehabilitation period that typical...

**Who might be able to join this trial:** - People who have been formally diagnosed with a stroke for the first time, confirmed according to standard diagnostic requirements - People whose lower limb movement after stroke is moderately to severely affected, based on a standard assessment score below 34 out of 34 (Fugl-...

**Who might be able to join this trial:** - People aged 19 years or older - People who have a significant narrowing of the carotid artery (a major blood vessel in the neck) — either more than 50% narrowing with symptoms, or more than 70% narrowing without symptoms — and who are planned to have or have already had a st...

**Who might be able to join this trial:** - People who have had an ischemic or hemorrhagic stroke that was confirmed by a CT scan or MRI. - People who had their stroke at least 6 months ago. - People who have at least some ability to move the arm affected by their stroke (some movement in the shoulder, elbow, or wrist...

Who might be able to join this trial: - People who are suspected of having an acute ischemic stroke (a stroke caused by a blockage in a blood vessel in the brain) - People whose stroke is likely caused by a blockage in a large or medium-sized blood vessel in the brain - People aged 18 years or older - People who were f...

Who might be able to join this trial: - Adults aged 18 or older of any gender - People who are showing signs of an acute stroke or a brief stroke-like episode (sometimes called a "mini-stroke"), and who are able to take a combination of two blood-thinning medications at the time of screening - People who arrive within...

Who might be able to join this trial: - People aged 18 or older - People who have had their first-ever suspected or confirmed ischemic stroke (a stroke caused by a blocked blood vessel), identified through a physical examination and/or brain scan - People whose stroke symptoms began less than 72 hours before being enro...

Who might be able to join this trial: - People aged between 18 and 75 years old - People who have muscle stiffness in the ankle and foot (specifically the muscles that point the foot downward) following a stroke, rated as mild to moderate on a standard scale - People who have had their first stroke only - People whose...

**Who might be able to join this trial:** - People who had little to no disability before their stroke (scoring 0–2 on a standard pre-stroke disability scale) - People currently experiencing an acute ischemic stroke (a stroke caused by a blockage) that is considered moderate to severe based on a standard neurological...

Who might be able to join this trial: - People who have been diagnosed with stroke, confirmed by a CT scan or MRI. - People between the ages of 50 and 65 years old (both men and women). - People whose heart and circulation are medically stable. - People with sufficient mental clarity to understand and follow the study...

**Who might be able to join this trial:** - People who had a single stroke (either a blocked-artery stroke or a bleeding stroke) more than 6 months ago that caused difficulty with speech (dysarthria). - People between the ages of 18 and 75 years old. - People who speak English. - People whose speech is affected enough...

**Who might be able to join this trial:** - People aged 18 to 75 years old, either male or female (who are not pregnant) - People who have been diagnosed with an unruptured brain aneurysm (a bulge in a blood vessel in the brain that has not burst), confirmed by a specialised brain scan (such as CTA, MRA, or DSA) - Peop...

**Who might be able to join this trial:** - People who have been diagnosed with a stroke or have a traumatic injury and are being cared for by the Trauma & Acute Care Surgery team - People who currently have medical orders requiring them to drink thickened liquids or have restrictions on what liquids they can have - Pe...

**Who might be able to join this trial:** - People who have weakness or loss of movement in one arm or hand caused by a stroke (either a blocked or bleeding stroke), confirmed by a brain scan - People whose stroke happened more than three months ago - People who are unable to actively open their hand or extend their f...