If this is close to home

This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.

  • Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
  • Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
  • Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
  • Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
  • Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14

Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.

Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.

Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.

Phase 3 study for people with Stroke

Recruiting Phase 3

Sources: ClinicalTrials.gov Checked: 11 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 3
Sponsor University of Melbourne
Registry number NCT05105633
Started 29 November 2021 Today 16 October 2026 Estimated completion 1 May 2028

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Bankstown-Lidcombe Hospital Bankstown NSW Not yet recruiting
John Hunter Hospital Newcastle NSW Not yet recruiting
Liverpool Hospital Sydney NSW Recruiting
Gold Coast Hospital Gold Coast QLD Not yet recruiting
Princess Alexandra Hospital Woolloongabba QLD Recruiting
Royal Adelaide Hospital Adelaide SA Recruiting
Alfred Health Melbourne VIC Recruiting
Austin Hospital Melbourne VIC Recruiting
Box Hill Hospital Melbourne VIC Recruiting
Monash Health Melbourne VIC Not yet recruiting
Royal Melbourne Hospital Melbourne VIC Recruiting
Western Health Melbourne VIC Recruiting
Fiona Stanley Hospital Murdoch WA Recruiting
Grampians Health Ballarat Australia Recruiting
Northern Hospital Melbourne Australia Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice

Who can join

Age 18 Years and over
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 688

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

* Patients presenting with posterior circulation ischemic stroke symptoms due to partial or complete basilar artery occlusion within 24 hours from symptom onset (or clinical deterioration/coma) or the time the patient was last known to be well.

* Patient's age is ≥18 years

* Presence of basilar artery occlusion, proven by CT Angiography or MR Angiography. Basilar artery occlusion is defined as 'potentially retrievable' occlusion at the basilar artery. This can be a partial or complete occlusion.

* Premorbid mRS ≤3 (independent function or requiring only minor domestic assistance and able to manage alone for at least 1 week).

* Local legal requirements for consent have been satisfied.

Exclusion Criteria:

* Intracerebral hemorrhage (ICH) or other diagnosis (e.g. tumour) identified by baseline imaging.

* Posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS) \<7 on non-contrast CT, CT Angiography source images or DWI MRI.

* Significant cerebellar mass effect or acute hydrocephalus.

* Established frank hypodensity on non-contrast CT indicating subacute infarction.

* Bilateral extensive brainstem ischemia.

* Strong suspicion of underlying intracranial atherosclerotic disease (e.g diffuse arterial calcifications, basilar stenosis) or dissection which may require immediate neuro-interventional procedure with intracranial stenting and not benefit from intravenous thrombolysis at investigator's discretion.

* Pre-stroke mRS of ≥4 (indicating moderate to severe previous disability).

* Other standard contraindications to intravenous thrombolysis.

* Contraindication to imaging with contrast agents.

* Clinically evident pregnant women.

* Current participation in another research drug treatment protocol.

* Known terminal illness such that the patients would not be expected to survive a year.

* Planned withdrawal of care or comfort care measures.

* Any condition that, in the judgment of the investigator could impose hazards to the patient if study therapy is initiated or affect the participation of the patient in the study.

Dates on the record

Started 29 November 2021
Estimated completion 1 May 2028
Registry last updated 6 May 2026
Checked by Voxsanity 11 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 6 May 2026.
  • This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.