Myasthenia Gravis
Clinical trials recruiting in Australia for Myasthenia Gravis, as the public registries list them.
Also called: Acquired myasthenia; Autoimmune myasthenia gravis; MG
At a glance
8 trials recruiting in Australia
4 states or territories with a listed site
0 started recruiting in the last 30 days
127 trials recruiting overseas
11 October 2026 date last checked
Where the trials are
Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.
4 listed sites on this page do not say which state they are in, so the counts above are lower than the real number of sites in some states. The trials themselves are all listed below.
Trials for Myasthenia Gravis
8 of 8 trials shown.
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Not a phased study
Study for people with Myasthenia Gravis
Where- Online Patient Enrollment System, Sydney — Recruiting
Who can join Age child, adult, older adult. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Sanford HealthTimelineStarted 1 July 2010 Today 16 October 2026 Estimated completion 1 December 2100NCT01793168 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Myasthenia Gravis
Where- Melbourne Neurology Group, North Melbourne (VIC) — Completed
- Gold Coast University Hospital, Southport (QLD) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Janssen Research & Development, LLCTimelineStarted 15 July 2021 Today 16 October 2026 Estimated completion 17 November 2023Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.
NCT04951622 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Myasthenia Gravis
Where- Westmead Institute for Medical Research, Westmead — Recruiting
Who can join Age 18 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Kyverna TherapeuticsTimelineStarted 28 August 2024 Today 16 October 2026 Estimated completion 1 September 2027NCT06193889 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Myasthenia Gravis
WhereNo Australian site on this record is listed as recruiting right now, even though the trial itself is open. Check with the site or the official record before travelling.
- Research Site, Melbourne (VIC) — Not yet recruiting
Who can join Age child, adult, older adult. Sex Female participants only. Healthy volunteers Not accepted.Sponsor Alexion Pharmaceuticals, Inc.TimelineStarted 16 December 2024 Today 16 October 2026 Estimated completion 11 July 2034NCT06312644 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Myasthenia Gravis
Where- Royal Children's Hospital Melbourne, Melbourne (NSW) — Recruiting
- Sydney Children's Hospital, Randwick (NSW) — Recruiting
Who can join Age 2 Years to 17 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor argenxTimelineStarted 28 June 2024 Today 16 October 2026 Estimated completion 1 September 2027NCT06392386 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Myasthenia Gravis
Where- Brain and Mind Research Institute, Camperdown (NSW) — Recruiting
- Sunshine Coast University Hospital, Birtinya (QLD) — Recruiting
- Princess Alexandra Hospital - PARENT, South Brisbane (QLD) — Recruiting
- John Hunter Hospital - PARENT, City of Burnside (SA) — Recruiting
- Box Hill Hospital - PARENT, Box Hill (VIC) — Recruiting
- Gold Coast University Hospital - PARENT, Southport — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, GermanyTimelineStarted 25 June 2024 Today 16 October 2026 Estimated completion 23 August 2028NCT06463587 · Checked 11 October 2026
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Recruiting Phase 1
Phase 1 study for people with Myasthenia Gravis
Where- Concord Repatriation General Hospital, Sydney (NSW) — Recruiting
- Corner Hawkesbury Road and Darcy Road, Westmead (NSW) — Recruiting
Who can join Age 18 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Kite, A Gilead CompanyTimelineStarted 10 April 2026 Today 16 October 2026 Estimated completion 1 June 2029NCT07304154 · Checked 11 October 2026
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Recruiting Phase 2
Phase 2 study for people with Myasthenia Gravis
Where- Eastern Health - Box Hill Hospital, Box Hill — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Vertex Pharmaceuticals IncorporatedTimelineStarted 13 May 2026 Today 16 October 2026 Estimated completion 2 March 2029NCT07501702 · Checked 11 October 2026
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voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice
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Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.
Trials overseas
127 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
About Myasthenia Gravis
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
What is myasthenia gravis? Myasthenia gravis, sometimes called MG, is a chronic (long-lasting) disease that causes weakness in your voluntary muscles. The voluntary muscles are the ones that you can control. They include the muscles you use for: - Eye and eyelid movement - Facial expressions - Chewing - Talking - Swallowing - Breathing - Moving your arms and legs You can also have weakness in other muscles. This weakness gets worse with activity, and better with rest. Myasthenia gravis is a type of autoimmune disease. In autoimmune diseases, your immune system attacks the healthy cells of your organs and tissues by mistake. What causes myasthenia gravis? Myasthenia gravis is caused by an error in how nerve signals are sent to muscles. These signals get blocked at the nerve-muscle junction. This junction is the place where the nerve endings connect with the muscles they control. Normally, this is how the signals work: - The signals travel down a nerve that controls movement in the muscle - The nerve endings release a substance called acetylcholine - Acetylcholine binds to the muscle tissue at the nerve-muscle junction - This causes the muscle to contract (move) But in someone with myasthenia gravis, the body's own immune system makes antibodies that block the binding of acetylcholine to the muscle. This makes the muscles weaker. The thymus gland, which is part of your immune system, may play a role in myasthenia gravis. Normally, your thymus gland is active and growing when you are a child. It makes white blood cells to fight infections. At puberty, it starts getting smaller and is replaced by fat. It is usually small by the time you are an adult. But in many adults with myasthenia gravis, the thymus gland stays large. And some people with myasthenia gravis can get thymomas, which are tumors of the thymus. The are usually benign (not cancer), but they can sometimes become cancerous. Who is more likely to develop myasthenia gravis? Although myasthenia gravis can affect people of any age, it is most common in young adult women (under age 40) and older men (over age 60). It is usually not inherited (passed down in families). Myasthenia gravis normally does not affect infants. But if you are pregnant and have myasthenia gravis it's possible to pass the antibodies to your fetus. The baby can then be born with neonatal myasthenia. This condition is usually temporary, and the symptoms typically go away within two to three months after birth. What are the symptoms of myasthenia gravis? The symptoms of myasthenia gravis will depend on which muscles are affected. The symptoms often include: - Weakness of the eye muscles - Drooping of one or both eyelids - Blurred or double vision - Changes in facial expressions - Trouble swallowing - Shortness of breath - Speech problems - Weakness in the arms, hands, fingers, legs, and neck Different people have different levels of muscle weakness. And the weakness can vary from day to day. Some days it might be mild, and other days it might be worse. Physical activity often makes the muscle weakness worse. Some people with myasthenia gravis can get severe weakness that affects the muscles that control breathing. This is called a myasthenic crisis, and it is a life-threatening emergency. How is myasthenia gravis diagnosed? There are many other conditions that can cause muscle weakness, so myasthenia gravis can be hard to diagnose. To find out if you have myasthenia gravis, your health care provider: - Will ask about your medical history and symptoms - Will do a physical exam, including a neurological exam - Will likely order tests for myasthenia gravis, including: - Blood tests - Imaging tests - Electromyography (EMG) and nerve conduction studies What are the treatments for myasthenia gravis? There is no cure for myasthenia gravis, but treatments that can improve muscle weakness and help with symptoms. They include: - Anticholinesterase medicines, which can improve nerve-to-muscle messages and make muscles stronger. - Immunosuppressive medicines, which are medicines that decrease your body's immune system responses. They can lower your body's production of abnormal antibodies. - Monoclonal antibodies, which can also help decrease your body's immune system responses. - Plasmapheresis (plasma exchange) and intravenous immunoglobulin, which are procedures to remove abnormal antibodies from your blood. They are usually used in severe cases. They can help with symptoms for a few weeks or months. - Thymectomy, surgery to remove the thymus gland. It can reduce the symptoms of myasthenia gravis, possibly by rebalancing the immune system. Lifestyle changes may be helpful for some people. The changes could include regular gentle exercise, getting enough rest, and eating healthy foods. Some people with myasthenia gravis go into remission. This means that they do not have symptoms. The remission is usually temporary, but sometimes it can be permanent. NIH: National Institute of Neurological Disorders and Stroke
US source; availability in Australia may differ.
Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- ClinicalTrials.gov processing date: 28 September 2026.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
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