Multiple Sclerosis Trial, Recruiting NCT05964829 Sponsor: Cionic, Inc. Condition: Multiple Sclerosis
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Multiple Sclerosis Trial, Recruiting

NCT05964829
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with relapsing-remitting or progressive forms of multiple sclerosis (MS) who are between 22 and 75 years old
  • People who are able to walk for at least 15 minutes throughout the day, five days a week, with or without a walking aid
  • People who have adequate thinking and communication abilities, as assessed by a phone-based cognitive screening test used to rule out dementia
  • People who are able to wear the Neural Sleeve device for up to 8 hours per day
  • People whose walking speed falls within a specific range, measured by a timed 25-foot walk test (between 8 and 45 seconds to complete)
  • People whose MS medications and symptoms have been stable for at least the past 60 days, with no recent changes or flare-ups
  • People whose MS-related disability falls within a specific range, as measured by recognised MS disability scoring tools (confirm with trial site for exact score requirements)

Who may not be able to join:

  • People with nerve damage or injury in the lower body (such as peripheral neuropathy) that could affect how muscles respond to electrical stimulation
  • People who have no feeling in the more affected leg
  • People whose muscles do not respond adequately to electrical stimulation, or who cannot tolerate the stimulation
  • People who are unable to walk with the Neural Sleeve worn in place of their current leg brace or ankle/foot support, if they use one
  • People who fall more than once a week
  • People who have used a functional electrical stimulation (FES) device in the past year
  • People who have a demand-type heart pacemaker or defibrillator
  • People who have a cancerous tumour in the more affected leg
  • People who have a blood clot (thrombosis) in the more affected leg
  • People who have a fracture or joint dislocation in the more affected leg that could be made worse by muscle movement caused by stimulation

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Douglas A Wajda, PhD, Cleveland State University

Phone: 3308837149

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Cionic, Inc.
Registry
ClinicalTrials.gov
Start date
4 September 2023
Est. completion
1 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Gait Speed; Change in Perceived Walking Ability; Change in MS Disability; Amount of Daily Walking/Activity Level; Duration of Daily Walking/Activity Level

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov