Phase 1 Multiple Sclerosis Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People between the ages of 50 and 85 who have been diagnosed with secondary progressive multiple sclerosis (a specific form of MS) using the 2024 McDonald Criteria.
- People who have not been treated with a disease-modifying therapy for MS in the last 6 months, or who have previously used one of three specific MS treatments: alemtuzumab, cladribine, or mitoxantrone.
- People whose MS has shown signs of getting worse over the past 12 months.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People with unstable coronary artery disease, including a heart attack within the last 6 months or ongoing chest pain (angina).
- People who have been hospitalised for any reason within the last 6 months.
- People who have had a stroke or a brief stroke-like episode (sometimes called a "mini-stroke") in the past 6 months.
- People who have a condition called pulmonary arterial hypertension, which is high blood pressure in the lungs.
- People with a current or long-term history of liver disease.
- People who have been diagnosed with Alzheimer's disease or Parkinson's disease.
- People who have had a problem with drug or alcohol misuse at any point in the last 5 years.
- People with a history of blood clotting disorders, bleeding in the brain, or bleeding in the digestive system.
- People with any history, at any point in their life, of chest pain (angina), heart attack, irregular heartbeat, or heart failure.
- People with a heart electrical abnormality known as QTc prolongation (confirm with trial site).
- People with low levels of red blood cells, platelets, or certain white blood cells below specific thresholds measured by blood tests.
- People with moderately low levels of potassium or magnesium in their blood, based on specific laboratory measurements.
- People whose liver function blood test results are above certain levels, indicating possible liver stress (confirm with trial site).
- People with chronic kidney disease where kidney filtering function falls below a specific level measured by a blood test.
- People who drink more than 2 alcoholic drinks per day (for men) or more than 1 alcoholic drink per day (for women).
- People who take certain heart medications known to affect heart rhythm (specifically those that cause QTc prolongation).
- People who take antipsychotic or anti-anxiety medications.
- People who take blood-thinning or anti-clotting medications, except for aspirin.
- People who take a type of antibiotic called quinolone antibiotics.
- People who are pregnant, breastfeeding, planning to become pregnant, or planning to donate eggs or sperm during the trial.
- People whose levels of a specific biological marker called p16INK4a are below a certain threshold established from a separate MS research group (confirm with trial site).
- People who take medications that are broken down by the same liver pathways as the trial drugs (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Participant retention rate; Recruitment feasibility; Frequency of adverse drug effects of dasatinib and quercetin
Can't join this trial?
Data last synced from ClinicalTrials.gov: 24 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.