Multiple Sclerosis Trial, Recruiting NCT03981003 Sponsor: Centre Hospitalier Universitaire de Nīmes Condition: Multiple Sclerosis
Back to Multiple Sclerosis

Multiple Sclerosis Trial, Recruiting

NCT03981003
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been fully informed about the trial and have signed a consent form agreeing to take part.
  • People who are covered by a health insurance plan.
  • People who are 15 years old or older.
  • People who have been diagnosed with Multiple Sclerosis (MS) according to recognised 2017 diagnostic guidelines.
  • People who are already participating in a related study called the OFSEP-HD cohort (an linked study that this trial is connected to).
  • People whose MS-related disability level falls within a specific range on a standard medical scale (scored 0 to 7.0 — confirm with trial site for what this means for a specific case).
  • People who are taking MS medications or those who are not — both may be eligible.
  • For one part of the trial (Work Package 3): people whose MS has been active during follow-up, meaning they have had a relapse, a worsening of disability, or new activity seen on a brain scan.
  • For another part of the trial (Work Package 4): people whose MS has been stable, and who are being followed at either Nîmes or Nantes University Hospitals.

Who may not be able to join:

  • People who have taken part in another interventional (hands-on) study in the past three months that could affect this trial's results.
  • People who are currently in a waiting-out period required after a previous study.
  • People who are under judicial protection (a legal status where a court oversees their affairs).
  • People who are not able to be properly informed about the study, for example due to a language barrier or difficulty understanding the information.
  • People who are pregnant or breastfeeding.
  • People who are under 15 years old.
  • People who are unable to answer questionnaires.
  • People who have had a single episode that could suggest MS (called a Clinically Isolated Syndrome) but do not yet meet the full MS diagnosis criteria.
  • People who have MS-like changes visible on a brain scan but have never had any symptoms (called Radiologically Isolated Syndrome).
  • People who have a condition called Neuromyelitis Optica Spectrum Disorder, which is a separate condition from MS.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Eric Thouvenot, CHU Nimes

Phone: +33.(0)4.66.68.32.61

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centre Hospitalier Universitaire de Nīmes
Registry
ClinicalTrials.gov
Start date
22 May 2019
Est. completion
1 June 2028

Where this trial is recruiting

🇫🇷 France Martinique

Primary endpoints

Serum Neurofilament Light Chain level in patients with evolving disease compared to those with stable disease; GFAP level in patients with evolving disease compared to those with stable disease; Serum Neurofilament Light Chain level in patients with evolving disease compared to those with stable disease; GFAP level in patients with evolving disease compared to those with stable disease; Serum Neurofilament Light Chain level in patients with evolving disease compared to those with stable disease; GFAP level in patients with evolving disease compared to those with stable disease; Serum Neurofila...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov