Multiple Sclerosis Trial, Recruiting NCT07292480 Sponsor: Centre Hospitalier Universitaire de Nīmes Condition: Multiple Sclerosis
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Multiple Sclerosis Trial, Recruiting

NCT07292480
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with relapsing-remitting multiple sclerosis (a form of MS with flare-ups and periods of recovery) according to 2024 diagnostic guidelines.
  • People whose MS symptoms first appeared less than 10 years ago.
  • People whose MS has shown signs of activity in the last 24 months, such as a relapse or new or growing lesions visible on MRI scans compared to a previous MRI taken within the last 24 months (plus or minus 3 months).
  • People currently taking a first-line MS medication (such as interferon, glatiramer acetate, teriflunomide, or fumarates) for less than 24 months.
  • People who have had a standard MRI follow-up scan within the 90 days before joining the trial.
  • People whose MS has been clinically stable for at least 30 days before joining.
  • People already enrolled in certain MS observational studies or registries (such as OFSEP or PROMISE) may also be eligible.
  • Women who could become pregnant must have a negative pregnancy test at the time of joining and must use an effective method of contraception throughout the trial.
  • People who are able to attend all scheduled trial visits.
  • People who have signed a consent form agreeing to take part.
  • People who are covered by a health insurance plan.

Who may not be able to join:

  • Women who are pregnant or breastfeeding.
  • People who are unable to have brain and/or spinal cord MRI scans.
  • People who are not willing to have monthly blood draws.
  • People currently taking higher-intensity MS treatments, including medications such as natalizumab, ocrelizumab, alemtuzumab, cladribine, or similar drugs.
  • People who have had a relapse within the 6 months before joining.
  • People whose most recent MRI (within 3 months before joining) showed actively inflamed lesions (known as contrast-enhancing lesions).
  • People with progressive MS (a form of MS that worsens steadily rather than in flare-ups).
  • People who are unable to sign a consent form.
  • People for whom it is not possible to provide adequate information about the trial.
  • People already taking part in another clinical treatment trial, or who are within a waiting period after a previous trial (based on how long the previous trial drug stays in the body).
  • People under judicial protection or adults under legal guardianship.
  • Women of reproductive potential who are not willing to use effective contraception for the duration of the trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Eric Thouvenot, Centre Hospitalier Universitaire de Nīmes

Phone: 04 66 68 32 61

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centre Hospitalier Universitaire de Nīmes
Registry
ClinicalTrials.gov
Start date
12 December 2025
Est. completion
1 December 2030

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Time to evidence of disease activity between groups; Time to evidence of disease activity between groups

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov