Phase 2 Multiple Sclerosis Trial, Recruiting NCT06599307 Sponsor: Cairo University Condition: Multiple Sclerosis
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Phase 2 Multiple Sclerosis Trial, Recruiting

NCT06599307
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with secondary progressive multiple sclerosis (a form of MS where disability gradually worsens over time), confirmed using a specific set of diagnostic standards that measure how much disability has progressed and over what period of time (confirm with trial site for full details)
  • People whose MS-related disability level, measured on a standard scale used by neurologists, is rated at 6.5 or above at the start of the trial

Who may not be able to join:

  • People who have previously taken MS-modifying medications other than a drug called rituximab
  • People who have had an MS relapse (a sudden worsening of symptoms) within the 3 months before joining the trial
  • People who have a known allergy or medical reason why rituximab would not be safe for them
  • People who have another neurological condition (a condition affecting the brain or nervous system) that could affect their thinking, memory, or hand and arm function

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Maha Atef Zaki, MD Neurology, Department of Neurology, Faculty of Medicine, Cairo University

Phone: 00201005393868

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 August 2024
Est. completion
1 September 2026

Where this trial is recruiting

🇪🇬 Egypt

Primary endpoints

The effect of rituximab on cognitive functions assessed by The Symbol Digit Modalities Test; The effect of rituximab on cognitive functions assessed by The Brief Visuospatial Memory Test-Revised; The effect of rituximab on cognitive functions assessed by The California Verbal Learning Test-II; The effect of rituximab on hand functions assessed by The Nine-Hole Peg Test

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov