Multiple Sclerosis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For the Ublituximab (treatment) group:
- You are between 18 and 65 years old
- You have been diagnosed with relapsing MS (including relapsing-remitting MS or active secondary progressive MS) based on recognised diagnostic guidelines
- Your doctor has recently referred you to start a medication called ublituximab for your MS
For the Comparison group:
- You are between 18 and 65 years old
- You have been diagnosed with relapsing-remitting MS based on recognised diagnostic guidelines
- You are currently on a steady, unchanged MS medication and do not plan to switch treatments within the next year
Who may not be able to join:
For the Ublituximab group:
- You have a known eye condition (such as diabetic eye disease, macular degeneration, or glaucoma) that could interfere with the study's eye tests
- You have received certain MS medications that reduce B-cells (such as rituximab, ocrelizumab, ofatumumab, or ublituximab) within the past 12 months
- You have had a serious or life-threatening reaction to ublituximab or a similar type of medication in the past
- You have an ongoing or serious infection, such as active hepatitis B, tuberculosis, or HIV, that would make this type of treatment unsafe
- You have received a live or weakened-live vaccine within 4 weeks before your first dose of ublituximab
For the Comparison group:
- You have a known eye condition (such as diabetic eye disease, macular degeneration, or glaucoma) that could interfere with the study's eye tests
- You have taken certain MS medications that reduce B-cells (such as rituximab, ocrelizumab, ofatumumab, or ublituximab) in the past 12 months, or you plan to start one within the next year
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Daniel Harrison, MD, University of Maryland, Baltimore
Phone: 410-328-1885
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Evaluation of the effect of ublituximab on macular hyperreflective foci (HRF) in MS.; Evaluation of the effect of ublituximab on inner limiting membrane (ILM) macrophage-like cells (MLC).
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.