Phase 3 Multiple Sclerosis Trial, Recruiting NCT06675955 Sponsor: Hoffmann-La Roche Condition: Multiple Sclerosis
Back to Multiple Sclerosis

Phase 3 Multiple Sclerosis Trial, Recruiting

NCT06675955
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who were receiving ongoing ocrelizumab treatment in one of a specific list of related earlier studies (called "parent studies") at the time of transferring into this trial, and for whom ocrelizumab treatment is not available locally.
  • People whose first dose in this extension trial will be given no earlier than 5 months after their last treatment dose in the parent study.
  • People who can produce a negative pregnancy test (urine) within 24 hours before their first dose in this trial, if they are of childbearing potential.

Who may not be able to join:

  • People for whom ocrelizumab is commercially available and reasonably accessible in their country for their specific condition.
  • People for whom ocrelizumab is available through a Post Trial Access Program (a scheme that provides continued access to a study treatment after a trial ends) in their country.
  • People who permanently stopped the study treatment for any reason during the parent study, or in the period between their last parent study dose and their first dose in this extension trial.
  • People who have any condition that, in the investigator's opinion, could interfere with assessing their safety or could put them at high risk of treatment-related complications.
  • People who are currently participating in another therapeutic clinical trial (other than the parent study).
  • People who have a weakened immune system.
  • People who have a known active cancer, or who are being actively monitored for cancer returning.
  • People who have other known neurological conditions (conditions affecting the brain, spinal cord, or nerves).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Clinical Trials, Hoffmann-La Roche

Phone: 888-662-6728 (U.S. Only)

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
13 December 2024
Est. completion
31 December 2029

Where this trial is recruiting

🇫🇷 France 🇩🇪 Germany 🇷🇺 Russia 🇺🇦 Ukraine

Primary endpoints

Change From Baseline to End of Study in the Physical Functioning Score of the Patient-Reported Outcome Measure Information System/Quality of Life in Neurological Disorders - Physical Function Measure for Multiple Sclerosis 15a (PROMISnq PFMS-15a); Number of Eligible Participants who Have Received Access to Ocrelizumab in the Study

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov