Multiple Sclerosis Trial, Recruiting NCT05357781 Sponsor: Insel Gruppe AG, University Hospital Bern Condition: Multiple Sclerosis
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Multiple Sclerosis Trial, Recruiting

NCT05357781
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Multiple Sclerosis (MS) using standard diagnostic guidelines called the McDonald 2017 criteria
  • You are between 18 and 65 years old
  • Your MS has been stable for the past 12 months, meaning no relapses, no new activity on brain/spine scans, and no worsening of disability
  • You have been on the same MS medication without any changes for the past 12 months
  • You are fully able to walk without significant difficulty (confirmed by a standard MS disability scale score below 4)
  • You are able to read, understand, and sign a consent form yourself

Who may not be able to join:

  • You have severe depression (based on a standard depression questionnaire score) or another diagnosed psychiatric condition
  • You have a serious problem with your immune system, other than a specific condition involving low antibody levels in the blood
  • You are currently receiving, or have been told you need, immunoglobulin (antibody) replacement treatment
  • You experience very severe daytime sleepiness, based on a standard sleepiness questionnaire score
  • You have certain conditions or take certain medications that could worsen fatigue, such as liver, kidney, or thyroid problems, substance misuse, use of tranquilisers, anti-epileptic drugs, or psychiatric medications, or a long-term infectious disease such as hepatitis or HIV
  • You have another neurological degenerative condition or another autoimmune disease alongside your MS
  • You are not able to give written consent yourself
  • You are under 18, pregnant, or currently in prison

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Lara Diem, MD, Inselspital University Hospital of Bern

Phone: 0041316327000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Insel Gruppe AG, University Hospital Bern
Registry
ClinicalTrials.gov
Start date
1 July 2022
Est. completion
30 December 2026

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

Number of patients with fatigue and hypogammaglobulinemia; Number of patients with fatigue without hypogammaglobulinemia

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov