Multiple Sclerosis Trial, Recruiting (NCT07012135)

Multiple Sclerosis Trial, Recruiting NCT07012135 Sponsor: Mayo Clinic Condition: Multiple Sclerosis

Printed from Voxsanity (voxsanity.com.au) — NCT07012135 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Multiple Sclerosis

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

People aged between 18 and 50 years old
People who have a clinically confirmed diagnosis of multiple sclerosis, or people who are healthy and have not experienced a neurological injury (as a comparison group)

Who may not be able to join:

People who have symptoms of heart or blood vessel conditions (such as high blood pressure, stroke, or chest pain), breathing conditions, nerve conditions affecting the limbs, or autonomic nervous system conditions — particularly diabetes that requires medication
Women who are currently pregnant or breastfeeding
People with a body mass index (BMI) of 35 or higher (BMI is a measure based on height and weight)
People who are currently taking a medication that is known to potentially interact badly with a drug called phenylephrine
People who, in the opinion of the lead researcher or their clinical colleague, have any illness or condition that could make it difficult to follow the trial procedures, could put their safety at risk, or could affect how the trial results are interpreted (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 27 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ryan J. Solinsky, MD, Mayo Clinic

Phone: 507-284-9298

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07012135

Sponsor: Mayo Clinic

Phase: Not Applicable

Status: Recruiting

Condition: Multiple Sclerosis

Trial contact: 507-284-9298

More information: https://clinicaltrials.gov/study/NCT07012135

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

People aged between 18 and 50 years old
People who have a clinically confirmed diagnosis of multiple sclerosis, or people who are healthy and have not experienced a neurological injury (as a comparison group)

Who may not be able to join:

People who have symptoms of heart or blood vessel conditions (such as high blood pressure, stroke, or chest pain), breathing conditions, nerve conditions affecting the limbs, or autonomic nervous system conditions — particularly diabetes that requires medication
Women who are currently pregnant or breastfeeding
People with a body mass index (BMI) of 35 or higher (BMI is a measure based on height and weight)
People who are currently taking a medication that is known to potentially interact badly with a drug called phenylephrine
People who, in the opinion of the lead researcher or their clinical colleague, have any illness or condition that could make it difficult to follow the trial procedures, could put their safety at risk, or could affect how the trial results are interpreted (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 27 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Mayo Clinic

Registry

ClinicalTrials.gov

Start date

17 September 2025

Est. completion

31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Valsalva Maneuver Phase II

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov