Phase 2 Obesity Trial, Recruiting NCT03418857 Sponsor: Penn State University Condition: Obesity
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Phase 2 Obesity Trial, Recruiting

NCT03418857
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with a body mass index (BMI) between 25 and 35 (a measure of body weight relative to height that falls in the overweight to moderately obese range)
  • People with a larger-than-average waist size — at least 94 cm for men or at least 80 cm for women
  • People who also have at least one of the following: high triglycerides (a type of fat in the blood) at 150 mg/dL or above; low "good" (HDL) cholesterol — 40 mg/dL or below for men, or 50 mg/dL or below for women; elevated blood pressure (130 mmHg systolic or 85 mmHg diastolic or higher); or a fasting blood sugar level of 100 mg/dL or above

Who may not be able to join:

  • People with a dairy allergy
  • People who smoke or use any tobacco products
  • People with a systolic (top number) blood pressure of 160 mmHg or higher, or a diastolic (bottom number) blood pressure above 100 mmHg
  • People with a fasting blood sugar level of 126 mg/dL or above
  • People with a history of heart attack, heart disease, stroke, diabetes, liver disease, kidney disease, or thyroid disease (unless the thyroid condition is well-controlled with medication)
  • People who take cholesterol-lowering or lipid-lowering medications
  • People who take blood pressure-lowering or blood sugar-lowering supplements, including psyllium, fish oil capsules, soy lecithin, niacin, fibre, flax, phytoestrogens, or foods enriched with stanols or sterols
  • People who are unwilling to stop taking nutritional supplements, herbal products, vitamins, or other probiotic products during the trial
  • People who have been diagnosed with an inflammatory bowel disease, such as Crohn's disease or ulcerative colitis
  • People who have used antibiotics within the past two months
  • People who drink 14 or more standard alcoholic drinks per week
  • People who regularly use anti-inflammatory medications such as aspirin or ibuprofen

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 814 867 3716

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Penn State University
Registry
ClinicalTrials.gov
Start date
29 June 2018
Est. completion
1 October 2022

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change from baseline in inflammatory markers

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov