Leukaemia Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are covered by a social security health scheme or an equivalent benefit program
• People who have read, understood, and signed a written consent form agreeing to take part
• People aged 60 to 74 years old who have been diagnosed with a new or secondary form of acute myeloid leukemia (AML) — a type of blood cancer — with an intermediate or high-risk genetic profile, or with a related bone marrow condition called myelodysplastic syndrome (RAEB), and whose disease has gone into complete remission (fewer than 5% abnormal cells) after initial treatment
• People who have a medical reason why they cannot receive the standard high-intensity preparation treatment used before a conventional bone marrow transplant

Who may not be able to join:

• People whose AML has been classified as standard (lower) risk based on their genetic profile
• People diagnosed with a specific type of leukemia called promyelocytic leukemia with a particular genetic change known as t(15;17)
• People with a type of AML linked to specific genetic changes known as t(8;21) or inv(16) (confirm with trial site)
• People with a normal chromosome pattern and a genetic profile considered lower risk — specifically those with certain gene markers (NPM1+, FLT3-) or a double mutation in a gene called CEBPα, or people whose chronic myeloid leukemia has progressed to a later stage called blast phase
• People who are under legal guardianship, who have had their freedoms restricted, or who have any condition that may affect their ability to understand and agree to the consent process
• People who do not wish to participate

Important: Always verify eligibility with the trial site directly before applying.