Phase 2 Head and Neck Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 or older who have been medically diagnosed with squamous cell cancer of the head and neck
• People who are scheduled to receive radiotherapy or proton therapy aimed at curing their cancer
• People who are receiving the chemotherapy drug cisplatin as part of their treatment
• Women who could become pregnant must be using a reliable and effective form of birth control
• Men who could father a child must be using adequate contraception, including condoms with spermicide, and must not donate sperm for 90 days after the study ends
• People who have been fully informed about the trial and have signed a consent form agreeing to take part
• People who are reasonably active and able to care for themselves, with a daily activity score of 2 or less on a standard medical scale called the ECOG scale (confirm with trial site)
• People with a life expectancy of at least 6 months
• People whose blood, liver, kidney, and nutritional levels fall within acceptable ranges as measured by standard blood tests (confirm with trial site for specific values)

Who may not be able to join:

• People who have previously had radiotherapy to the head and neck
• People who currently have a significant active infection (viral, bacterial, or fungal) requiring treatment, unless that treatment was completed at least 14 days before starting the study
• People who are using certain unapproved treatments for mouth sores, including beta-carotene, tocopherol, laser treatment, silver-nitrate mouth brushing, or certain growth factor therapies, during or within 14 days before starting the study
• People who are using a product called Mugard
• People who are using prostaglandins, pentoxifylline, or leucovorin during or within 14 days before starting the study
• People who are using certain mouthwashes, including allopurinol, hydrogen peroxide, sucralfate, or chlorhexidine, during or within 14 days before starting the study
• People who have recently had a serious non-cancer medical complication that the trial doctor believes makes participation unsafe
• People who have taken part in another clinical drug trial within 28 days before starting this study
• People who have previously tested positive for HIV
• People who have a significant active illness at the time of screening that the trial doctor believes would prevent them from completing the study
• People whose treatment plan includes chemoradiation followed by additional chemotherapy afterward
• People who weigh less than 35 kg (77 lbs)
• People who are pregnant or breastfeeding
• People who are known to have a bad reaction or intolerance to platinum-based drugs (the group of drugs cisplatin belongs to)
• People with a history of insulin-dependent diabetes
• People who have Hepatitis B or Hepatitis C

Important: Always verify eligibility with the trial site directly before applying.