Early Phase 1 Cystic Fibrosis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with cystic fibrosis (CF)
• People aged 6 years or older
• People who have a specific CF gene mutation (CFTR mutation) that the study investigators believe may respond to approved CF medications called correctors or potentiators
• People who have provided informed consent (or assent, for younger participants)
• People whose CF lung treatment has been stable

Who may not be able to join:

• People who had a CF flare-up (exacerbation) requiring antibiotics or steroids within the 28 days before the trial starts
• People who are currently taking part in another clinical study involving CFTR modulator medications
• People who have smoked in the past 6 months
• People who have had a solid organ transplant (such as a lung, liver, or kidney transplant)
• People who have a condition that makes CFTR modulator medications unsafe to use, such as advanced liver scarring (cirrhosis) or severe kidney failure
• People who, in the opinion of the study investigator, have any other condition that would prevent safe participation in the trial
• People who are taking other medications that could interact significantly with CFTR modulators, or who are using CFTR modulators in a way not approved for their situation

Important: Always verify eligibility with the trial site directly before applying.