Phase 2 Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have cervical cancer that doctors believe can be treated with the goal of a cure, using radiation therapy (with or without chemotherapy) and a type of internal radiation called brachytherapy (BT)
• A biopsy has confirmed your cervical cancer is one of these types: squamous-cell carcinoma, adenocarcinoma, or adeno-squamous cell carcinoma
• Your cancer has been formally staged (measured and classified) using standard medical guidelines
• You have had an MRI scan of your pelvis at the time of diagnosis
• You have had an MRI, CT, or PET-CT scan of your abdomen and the area around your spine at the time of diagnosis
• You are able to have an MRI scan done while the brachytherapy applicator (a small device used to deliver internal radiation) is in place
• You may still be eligible if cancer has spread to certain lymph nodes in the lower part of the abdomen (below a specific spinal level called L1-L2)
• You are able and willing to give your informed consent to take part

Who may not be able to join:

• You have another active cancer, other than a very early-stage cervical abnormality or a common type of non-spreading skin cancer (basal cell carcinoma)
• Your cervical cancer is a rare type, such as small cell neuroendocrine cancer, melanoma, or other uncommon cervical cancers
• Your cancer has spread to areas beyond the lower abdominal lymph node region (above the L1-L2 spinal level)
• You have previously had radiation therapy to your pelvis or abdomen
• You have previously had surgery to remove all or part of your uterus (hysterectomy)
• Your treatment plan combines radiation given before surgery with an operation
• You are only receiving internal radiation (brachytherapy) without external radiation
• You are only receiving external radiation without internal radiation (brachytherapy)
• You are receiving chemotherapy before the main treatment, or any cancer treatment other than a specific weekly chemotherapy drug called cisplatin — although a specific course of chemotherapy after the main treatment (carboplatin and paclitaxel) may be allowed depending on your hospital's policy (confirm with trial site)
• You have a medical reason why you cannot have an MRI scan
• You have a medical reason why you cannot have brachytherapy (internal radiation)

Important: Always verify eligibility with the trial site directly before applying.