If this is close to home

This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.

Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14

Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.

Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.

Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.

Phase 3 study for people with Endometrial Cancer

Recruiting Phase 3

Sources: ClinicalTrials.gov Checked: 11 October 2026 Not medical advice

This trial at a glance

Status Recruiting

Phase Phase 3

Sponsor Queensland Centre for Gynaecological Cancer

Registry number NCT04073706

Started 18 January 2021 Today 16 October 2026 Estimated completion 1 January 2031

Where this trial is running

Trial sites and the status recorded for each
Site	City	State or country	Status at this site
Chris O'Brien Lifehouse	Camperdown	NSW	Recruiting
Liverpool Hospital	Liverpool	NSW	Recruiting
The Wesley Hospital	Auchenflower	QLD	Recruiting
Greenslopes Private Hospital	Brisbane	QLD	Recruiting
Buderim Private Hospital	Buderim	QLD	Recruiting
North West Private Hospital	Everton Park	QLD	Recruiting
Royal Brisbane and Women's Hospital	Herston	QLD	Recruiting
Mater Hospital	South Brisbane	QLD	Recruiting
Gold Coast University Hospital	Southport	QLD	Not yet recruiting
St Andrews War Memorial Hospital	Spring Hill	QLD	Recruiting
Mercy Hospital for Women	Heidelberg	VIC	Recruiting
Epworth Freemasons	Melbourne	VIC	Recruiting
Royal Women's Hospital	Parkville	VIC	Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice

Who can join

Age 18 Years and over

Sex Female participants only

Healthy volunteers Not accepted

Enrolment target 760

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

1. Females, over 18 years, with histologically confirmed primary epithelial cancer of the endometrium of any cell type or uterine carcinosarcoma (mixed malignant mullerian tumour);

2. Clinically stage I disease (disease confined to body of uterus);

3. Eastern Cooperative Oncology Group (ECOG) performance status of ≤2;

4. Signed written informed consent;

5. Participant must meet criteria for a laparoscopic or robotic surgical approach as determined by the treating physician (e.g. suitable for TH BSO, ability to tolerate Trendelenberg positioning)

6. All available clinical evidence (physical examination findings, or medical imaging such as CT, MRI or ultrasound) demonstrates no evidence of extrauterine disease

7. Myometrial Invasion on MRI of not more than 50%. (Only if participant is \<45yo, has ONLY Grade 1 EAC and wishes to retain their ovaries).

8. Negative (serum or urine) pregnancy test ≤ 30 days of surgery in pre-menopausal women and women \< 2 years after the onset of menopause.

Exclusion Criteria:

1. Evidence of extrauterine disease (apparent involvement of cervix, vagina, parametria, adnexa, lymph nodes, bladder, bowel or distant sites) by clinical examination and/or through medical imaging.

2. Enlarged retroperitoneal pelvic and/or aortic lymph nodes (\>1 cm) on medical imaging;

3. Estimated life expectancy of less than 6 months;

4. Patients who have absolute contraindications for adjuvant radiotherapy and/or chemotherapy;

5. Patients who have previously received radiation treatment to the pelvis

6. Serious concomitant systemic disorders incompatible with the study (at the discretion of the investigator);

7. Patient compliance and geographic proximity that do not allow adequate follow-up;

8. Patients with allergy to Indocyanine Green (ICG)

9. Patients who have had previous retroperitoneal surgery

10. Patients who require a retroperitoneal (pelvic +/- para-aortic) lymph node dissection (lymphadenectomy)

11. Other prior malignancies \<5 years before inclusion, except for successfully treated keratinocyte skin cancers, or ductal carcinoma of the breast insitu

12. Uterine perforation during endometrial tissue sampling

Dates on the record

Started 18 January 2021

Estimated completion 1 January 2031

Registry last updated 15 September 2026

Checked by Voxsanity 11 October 2026

Results, publications and the official record

No results are posted on the official record yet.
No publications are listed on the official record yet.
Official record and contacts on ClinicalTrials.gov – contact details for each site are kept there, and are not copied onto this page.

Sources and dates

ClinicalTrials.gov – the record this page reformats
ClinicalTrials.gov processing date: 15 September 2026.
This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.

Voxsanity

Clinical trials recruiting in Australia, from the public registries · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial, which may be relevant to my care:

Trial: NCT04073706

Sponsor: Queensland Centre for Gynaecological Cancer

Phase: Phase 3

Status: Recruiting

Condition: Endometrial Cancer

More information: https://clinicaltrials.gov/study/NCT04073706

Eligibility criteria, as the registry published them

Reproduced exactly, unedited. Written for researchers rather than for patients.

Inclusion Criteria:

Females, over 18 years, with histologically confirmed primary epithelial cancer of the endometrium of any cell type or uterine carcinosarcoma (mixed malignant mullerian tumour);
Clinically stage I disease (disease confined to body of uterus);
Eastern Cooperative Oncology Group (ECOG) performance status of ≤2;
Signed written informed consent;
Participant must meet criteria for a laparoscopic or robotic surgical approach as determined by the treating physician (e.g. suitable for TH BSO, ability to tolerate Trendelenberg positioning)
All available clinical evidence (physical examination findings, or medical imaging such as CT, MRI or ultrasound) demonstrates no evidence of extrauterine disease
Myometrial Invasion on MRI of not more than 50%. (Only if participant is <45yo, has ONLY Grade 1 EAC and wishes to retain their ovaries).
Negative (serum or urine) pregnancy test ≤ 30 days of surgery in pre-menopausal women and women < 2 years after the onset of menopause.

Exclusion Criteria:

Evidence of extrauterine disease (apparent involvement of cervix, vagina, parametria, adnexa, lymph nodes, bladder, bowel or distant sites) by clinical examination and/or through medical imaging.
Enlarged retroperitoneal pelvic and/or aortic lymph nodes (>1 cm) on medical imaging;
Estimated life expectancy of less than 6 months;
Patients who have absolute contraindications for adjuvant radiotherapy and/or chemotherapy;
Patients who have previously received radiation treatment to the pelvis
Serious concomitant systemic disorders incompatible with the study (at the discretion of the investigator);
Patient compliance and geographic proximity that do not allow adequate follow-up;
Patients with allergy to Indocyanine Green (ICG)
Patients who have had previous retroperitoneal surgery
Patients who require a retroperitoneal (pelvic +/- para-aortic) lymph node dissection (lymphadenectomy)
Other prior malignancies <5 years before inclusion, except for successfully treated keratinocyte skin cancers, or ductal carcinoma of the breast insitu
Uterine perforation during endometrial tissue sampling

A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a registered health practitioner to access unapproved therapeutic goods for individual patients.

Not medical advice. Voxsanity reformats information published by public registries. It does not give medical advice and is not a substitute for talking to your doctor.