Phase 2 Endometrial Cancer Trial, Recruiting NCT03624244 Sponsor: Centre Leon Berard Condition: Endometrial Cancer
Back to Endometrial Cancer

Phase 2 Endometrial Cancer Trial, Recruiting

NCT03624244
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older
  • People who have been confirmed by tissue biopsy or pathology testing to have a type of uterine cancer called low grade endometrial stromal sarcoma (ESS)
  • People whose cancer had spread beyond the uterus at the time of diagnosis, or whose tumour was accidentally ruptured during a hysterectomy operation
  • People who have been taking a hormone-blocking medication called an aromatase inhibitor (specifically Anastrozole, Exemestane, or Letrozole) for at least 24 months (if no measurable disease was present when treatment started) or at least 36 months (if measurable disease was present when treatment started)
  • People whose cancer is currently stable or responding to the aromatase inhibitor treatment at the time of joining the trial
  • People with a general health and activity level rated at 2 or below on a standard medical scale, meaning they are able to care for themselves but may not be able to do heavy physical activity (confirm with trial site)
  • People covered by health/medical insurance
  • People who have signed a consent form agreeing to take part before any trial procedures begin

Who may not be able to join:

  • People who are pregnant or breastfeeding
  • People currently taking other cancer treatments, whether standard or experimental
  • People with serious ongoing health conditions affecting the heart, liver, kidneys, or blood-forming system that could interfere with the trial (as assessed by the trial doctor)
  • People who have had a different type of cancer in the past, unless it was a minor skin cancer (basal cell or squamous cell) or a very early-stage cervical condition, or unless they have been cancer-free for at least 3 years
  • People taking certain other medications that are not permitted during this trial
  • People for whom the study medications are medically unsuitable based on official prescribing guidelines
  • People who legally require a guardian or third-party support to make decisions on their behalf (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Isabelle RAY-COQUARD, MD PhD, Centre Leon Berard

Phone: +33478782786

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Centre Leon Berard
Registry
ClinicalTrials.gov
Start date
23 January 2019
Est. completion
1 January 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Progression free survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov