Interstitial Lung Disease Trial, Completed (NCT03641742)

Interstitial Lung Disease Trial, Completed NCT03641742 Sponsor: Columbia University Condition: Interstitial Lung Disease

Printed from Voxsanity (voxsanity.com.au) — NCT03641742 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial (NCT03641742) involved two groups of participants: 27 people who had already been diagnosed with a familial form of interstitial lung disease (a condition where lung tissue becomes damaged or scarred) — referred to as "proband" participants — and 98 people considered "at-risk" because of a family connection to someone with the condition. All 125 participants who started the trial completed it, with no drop-outs recorded. The trial was looking at whether certain lung changes, called interstitial lung abnormalities (ILAs), could be spotted on CT chest scans in the at-risk group. The reported data shows that the primary outcome — identifying ILAs on CT chest scans, as assessed by a specialist radiologist — was measured in the 98 at-risk participants. Of this group, 85 participants showed no ILAs on their scans, while 13 participants did show ILAs. No additional outcome measures beyond this count were reported in the submitted results data. It is worth noting that the reported results cover only this one primary outcome measure, and no secondary outcome data appears to have been submitted to ClinicalTrials.gov for this trial. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

View full results on ClinicalTrials.gov ↗ · Read the linked publication on PubMed (PMID 26367186) ↗

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

If you do NOT have a diagnosed lung disease but may be "at risk":

You are 35 years old or older (those aged 40 and above will have a high-resolution CT scan, and those aged 40–65 may also be offered a bronchoscopy procedure)
You have a parent, sibling, or child who has been diagnosed with one of these conditions: Idiopathic Pulmonary Fibrosis, a specific type of scarring lung disease (NSIP with fibrosis), Chronic Hypersensitivity Pneumonitis with scarring, or an unclassifiable scarring lung condition
You have any type of lung disease involving scarring shown on a chest CT scan
You are able to give your written agreement to take part

If you are a smoker without a diagnosed lung disease:

You are at least 50 years old
You have smoked at least one pack of cigarettes per day for 30 years

If you already have a diagnosed scarring lung disease ("Proband"):

You are 18 years old or older
You have been diagnosed with one of the scarring lung conditions listed above, following standard medical guidelines
You are able to give your written agreement to take part

Who may not be able to join:

If you are in the "at risk" group (no current lung disease diagnosis):

You have already been diagnosed with a lung disease affecting the lung tissue
You have used illegal drugs in the past year
You have had a lower lung infection (such as pneumonia) in the past 90 days
You have had a chest CT scan within the past year
You have a known history of heart failure, or chronic kidney or liver disease
You are currently pregnant or breastfeeding

If you are in the "already diagnosed" group:

You do not have any living parents, siblings, or children

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 22 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I found the following past clinical trial relevant to my condition, and wanted to raise it with you. It is no longer recruiting, but I wanted to ask whether similar active trials exist, or whether its results are relevant to my care:

Trial: NCT03641742

Sponsor: Columbia University

Phase: Not Applicable

Status: Completed

Condition: Interstitial Lung Disease

More information: https://clinicaltrials.gov/study/NCT03641742

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

If you do NOT have a diagnosed lung disease but may be "at risk":

You are 35 years old or older (those aged 40 and above will have a high-resolution CT scan, and those aged 40–65 may also be offered a bronchoscopy procedure)
You have a parent, sibling, or child who has been diagnosed with one of these conditions: Idiopathic Pulmonary Fibrosis, a specific type of scarring lung disease (NSIP with fibrosis), Chronic Hypersensitivity Pneumonitis with scarring, or an unclassifiable scarring lung condition
You have any type of lung disease involving scarring shown on a chest CT scan
You are able to give your written agreement to take part

If you are a smoker without a diagnosed lung disease:

You are at least 50 years old
You have smoked at least one pack of cigarettes per day for 30 years

If you already have a diagnosed scarring lung disease ("Proband"):

You are 18 years old or older
You have been diagnosed with one of the scarring lung conditions listed above, following standard medical guidelines
You are able to give your written agreement to take part

Who may not be able to join:

If you are in the "at risk" group (no current lung disease diagnosis):

You have already been diagnosed with a lung disease affecting the lung tissue
You have used illegal drugs in the past year
You have had a lower lung infection (such as pneumonia) in the past 90 days
You have had a chest CT scan within the past year
You have a known history of heart failure, or chronic kidney or liver disease
You are currently pregnant or breastfeeding

If you are in the "already diagnosed" group:

You do not have any living parents, siblings, or children

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 22 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Completed

Phase

Not Applicable

Sponsor

Columbia University

Registry

ClinicalTrials.gov

Start date

15 January 2018

Est. completion

11 February 2020

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of Participants With ILA (Interstitial Lung Abnormalities)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov