Head and Neck Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 or older
• People who are willing and able to sign a written consent form
• People whose general health and ability to carry out daily activities falls within a certain range, as measured by a standard cancer performance scale (ECOG score of 0–2)
• People who have been confirmed, through a tissue or cell sample, to have squamous cell carcinoma (a type of cancer)
• People whose cancer started in the oral cavity, oropharynx, nasal cavity, salivary glands (not including the parotid gland), hypopharynx, larynx, or whose cancer's starting point is unknown
• People whose treating cancer doctor has judged them suitable to receive high-dose cisplatin chemotherapy
• People whose treating radiation specialist has judged them suitable to receive radiation treatment aimed at curing the cancer
• People whose blood counts, liver function, and kidney function meet specific minimum levels (without needing a blood transfusion for at least 7 days before joining the trial) — confirm exact values with the trial site
• People who have been reviewed at a head and neck cancer specialist team meeting, including assessment by a radiation oncologist and a surgeon, before joining the trial

Who may not be able to join:

• People with serious other health conditions or other reasons that make chemotherapy or radiotherapy unsafe for them
• People who have had a head and neck cancer diagnosis within the past 5 years
• People whose cancer is confirmed or suspected to have started in the nasopharynx (the upper part of the throat behind the nose)
• People with significant hearing loss, as determined by a clinical assessment
• People who already use hearing aids
• People who have moderate or severe nerve damage causing symptoms such as numbness or tingling (peripheral neuropathy grade 2 or higher)
• People who have had, or are planned to have, chemotherapy before their combined chemotherapy and radiation treatment
• People who have had radiation treatment to the head or neck area at any time in the past
• People whose cancer has spread to distant parts of the body
• People who are unable to attend the full course of radiation treatment or required follow-up appointments
• People who have had another type of invasive cancer, unless they have been free of that cancer for at least 5 years — exceptions may apply for certain non-invasive or skin cancers (confirm with trial site)
• People who are unable or unwilling to complete quality-of-life questionnaires
• People who are pregnant or breastfeeding
• People who are unable or unwilling to use two methods of contraception at the same time

Important: Always verify eligibility with the trial site directly before applying.