Phase 2 Brain Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been confirmed by laboratory testing to have a Grade IV glioma (a type of brain tumour)
- People who have been recently diagnosed and are due to receive chemotherapy and/or radiation treatment
- People whose general physical functioning falls within a certain range, meaning they are able to carry out some or all daily activities (confirm with trial site for exact details)
- People aged 19 years or older
- People with a life expectancy of more than 6 months
- People who are able to read and sign a consent form agreeing to take part in the study
- Women who could potentially become pregnant must return a negative pregnancy test at the time of enrolment
- Women who could potentially become pregnant must either be post-menopausal (no periods for 2 or more years), have had a surgical procedure that prevents pregnancy, or be willing to use two forms of barrier contraception during the trial
Who may not be able to join:
- People who have significant loss of vision in part of their visual field that would prevent them from completing all study tests
- People who are unable to have an MRI scan
- People with severely reduced kidney function (as measured by a specific kidney function test falling below a certain level)
- People who screen positive for depression or anxiety at the time of enrolment
- People who are already taking an antidepressant medication (specifically SSRIs or SNRIs)
- People who have had problems tolerating SSRIs or SNRIs in the past
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Nicole A Shonka, MD, University of Nebraska
Phone: 402-836-9488
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Cognition; Characterize the degree of change in cognition and brain function; Change in Psycho-social Functions - PROMIS Neuro-QoL Item Bank v1.0 - Depression; Change in Psycho-social Functions - PROMIS Neuro-QoL Item Bank v1.0 - Anxiety; Change in Psycho-social Functions - PROMIS Neuro-QoL Item Bank v1.0 - Fatigue
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.