Phase 1 Lung Cancer Trial, Recruiting NCT03778814 Sponsor: Second Affiliated Hospital of Guangzhou Medical University Condition: Lung Cancer
Back to Lung Cancer

Phase 1 Lung Cancer Trial, Recruiting

NCT03778814
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with advanced lung cancer or another solid tumour where a tissue sample (biopsy) can be taken
  • People whose doctors estimate they are likely to live for more than 12 weeks
  • People whose liver function scores within a certain healthy range (a measure called the Child-Pugh-Turcotte score must be below 7 — confirm with trial site)
  • People whose heart, lungs, liver, and kidneys are all functioning at an adequate level
  • People whose specially prepared immune cells (T cells), made from their own blood, have been successfully modified in the laboratory to meet specific activity thresholds set by the trial
  • People who have read, understood, and signed an informed consent form, or whose legal guardian has done so on their behalf

Who may not be able to join:

  • People who have previously received any form of gene therapy
  • People whose tumour measures more than 25 cm in size
  • People with a serious viral infection such as hepatitis B (HBV), hepatitis C (HCV), or HIV
  • People with a known positive HIV diagnosis
  • People who have had a lung transplant in the past
  • People who currently have an active infection caused by bacteria, a virus, or fungi
  • People who are currently taking steroid medications at a daily dose of 0.5 mg of prednisone (or equivalent) per kilogram of body weight or higher
  • Women who are pregnant or currently breastfeeding
  • People with other serious medical conditions that the trial doctors consider make participation unsuitable
  • People with any other circumstances that the trial doctors consider make participation unsuitable

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Zhenfeng Zhang, MD,PhD, Second Affiliated Hospital of Guangzhou Medical University

Phone: 0086-020-34153532

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Second Affiliated Hospital of Guangzhou Medical University
Registry
ClinicalTrials.gov
Start date
1 December 2018
Est. completion
30 December 2029

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Number of Patients with Dose Limiting Toxicity

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov