Phase 4 ADHD Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Children who are pre-pubescent (at an early stage of physical development, such as Tanner stage 1 or 2)
• Children aged 7 to 12 years old (inclusive)
• Children whose parent or guardian has signed a consent form, and where the child has also given their agreement to participate
• Children whose parent communicates well enough in English to give informed consent and fill out assessment questionnaires
• Children who have been identified as having ADHD based on a structured parent interview (a computerised diagnostic tool called the C-DISC)
• Children whose ADHD symptoms score at a certain level on the ADHD Rating Scale-5, based on a parent interview
• Children whose ADHD symptoms are rated by their teacher at 1.5 standard deviations above what is typical for their age and sex on a scale called the SNAP
• Children who have been identified as having Conduct Disorder (CD), or severe Oppositional Defiant Disorder (ODD) with at least 2 additional Conduct Disorder symptoms, based on the C-DISC interview
• Children whose ODD or CD symptoms are rated by both a parent and a teacher at 1.5 standard deviations above what is typical for their age and sex on the SNAP scale

Who may not be able to join:

• Children with a significant neurological or medical illness
• Children with a history of head injury
• Children who were exposed to alcohol or drugs before birth
• Children who have been diagnosed with certain other psychiatric conditions, such as schizophrenia, bipolar disorder, major depression, generalised anxiety, social phobia, Tourette's Disorder, PTSD, or autism spectrum disorder
• Children who currently have thoughts of suicide, or who have previously attempted suicide
• Children who score below 75 on a standardised intelligence assessment called the WASI
• Children who have previously used or are currently using stimulant medications (note: prior or current use of non-stimulant medications may be permitted, but the child must have stopped taking any such medication at least 2 weeks before the study begins)
• Children who currently use or have previously used alcohol or drugs (confirmed through a diagnostic interview and urine testing)
• Children who have a psychological or medical condition that would prevent them from being safely or comfortably placed in a brain scanner — for example, claustrophobia or severe obesity
• Children who have metal in their body that cannot be removed before scanning, such as braces or a metal plate
• Children who have visual problems that could affect their ability to complete tasks during the study
• Children who have entered puberty early (Tanner stage above 2), or who are pregnant

Important: Always verify eligibility with the trial site directly before applying.