Phase 3 Endometrial Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- The person must be willing and able to sign a consent form and follow the study plan, as assessed by the study doctor.
- The person must have had a full hysterectomy and removal of both ovaries and fallopian tubes (either open surgery or keyhole surgery), with or without removal of lymph nodes.
- The person must have a confirmed diagnosis of uterine (endometrial) cancer at an early stage (FIGO Stage I or II, any grade), including certain specific cancer types such as serous, clear cell, and carcinosarcoma.
- The person must have no detectable cancer remaining after surgery.
- The person must have a general health and activity level rated at 0–2 on a standard medical scale (meaning they are able to carry out everyday activities, with or without some limitations) (confirm with trial site).
- The person must be 18 years of age or older.
- The person must have a life expectancy of at least 12 months.
Who may not be able to join:
- People whose cancer has spread to a more advanced stage (FIGO Stage III or IV), or whose treatment plan already includes external beam radiation therapy or chemotherapy directed at the cancer.
- People who have previously had radiation therapy to the pelvic area, or for whom additional pelvic radiation is already planned.
- People who have not yet recovered from the side effects of any treatment received more than 4 weeks before the study start date.
- People who would need more than 14 weeks between their surgery and starting radiation therapy as part of the study — unless they are also receiving chemotherapy, in which case radiation may begin within 6 months of surgery. Note: exceptions may be reviewed and approved by the study coordinating centre on a case-by-case basis.
- People who are currently taking part in another clinical trial, or who have received an experimental treatment within the 30 days before the study start date.
- People who are unwilling or unable to take part in a study-related procedure.
- People who are currently pregnant or breastfeeding.
- People who are currently incarcerated.
- People with a serious, uncontrolled medical condition that the study doctor believes would prevent them from safely receiving the study treatment.
- People with a history of certain brain or nervous system conditions, including primary brain tumours, seizures not controlled by standard medication, cancer that has spread to the brain, or a stroke, mini-stroke (TIA), or brain bleed within the six months before joining the study.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Kara Romano, MD, University of Virginia
Phone: 434-243-0008
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Female Sexual Function Index (FSFI); Preference Option Randomized Design (PORD)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.