Obesity Trial, Recruiting NCT03868592 Sponsor: Mayo Clinic Condition: Obesity
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Obesity Trial, Recruiting

NCT03868592
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with a Body Mass Index (BMI) between 40 and 50 kg/m² (a measure of body weight relative to height).
  • People without any active physical illness that would interfere with movement or weight loss following bariatric (weight loss) surgery.

Who may not be able to join:

  • People who have been diagnosed with Type 1 or Type 2 Diabetes, or who have a fasting blood sugar level of 126 mg/dL or higher.
  • People with active heart (coronary artery) disease.
  • People who currently take part in structured exercise more than twice a week for 30 minutes or longer per session.
  • People who currently smoke.
  • People who take certain medications known to affect how the body stores or processes fat, such as beta blockers or corticosteroids (confirm with trial site for a full list).
  • People with reduced kidney function, indicated by a specific blood marker (creatinine) above a certain level.
  • People with chronic active liver disease, indicated by certain liver-related blood test results being above set levels.
  • People who are currently pregnant or breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
1 August 2019
Est. completion
1 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

adipose macrophage content, adipose IL-6 and TNF gene expression; insulin regulation of lipolysis (IC50)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov