Endometrial Cancer Trial, Recruiting NCT04008563 Sponsor: University Health Network, Toronto Condition: Endometrial Cancer
Back to Endometrial Cancer

Endometrial Cancer Trial, Recruiting

NCT04008563
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Your Body Mass Index (BMI) is 35 or higher (a measure of body weight relative to height)
  • You have been diagnosed with either early-stage (Grade 1) uterine cancer of a specific type (endometrioid endometrial cancer) or a pre-cancerous condition of the uterine lining called complex atypical hyperplasia
  • Imaging scans (MRI or CT) show the cancer has not spread outside the uterus
  • You are generally well enough to carry out light activity and care for yourself (confirm with trial site)
  • You wish to preserve your ability to have children in the future
  • You are able to safely use a hormone-releasing coil (IUD) placed in the uterus
  • You have signed the official consent form agreeing to take part

Who may not be able to join:

  • Scans show the cancer has grown into the uterine wall or spread beyond the uterus
  • You have a more aggressive type of uterine cancer (high grade or p53 type)
  • You have a history of another cancer, unless it was fully treated with no signs of return for more than 5 years
  • You have previously had major surgery on the upper abdomen, such as weight-loss (bariatric) surgery, removal of the spleen, partial stomach removal, or bowel or liver surgery (note: appendix removal, gallbladder removal, hernia repair, and caesarean sections are acceptable)
  • You are currently taking weight-loss medication (note: people taking GLP-1 medications such as Ozempic specifically for diabetes treatment are not excluded)
  • You have medical reasons that make a type of weight-loss surgery called sleeve gastrectomy unsafe for you
  • You have a serious medical condition that is affecting how a major organ (such as the heart, kidneys, or liver) is working
  • You are unable to understand or take part in the consent process
  • You are currently pregnant
  • You have smoked in the last 6 months
  • You are currently struggling with a substance use disorder (such as alcohol or drug dependency)
  • You currently have an untreated or severe mental health condition

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Sarah E Ferguson, MD, University Health Network, Toronto

Phone: 416-946-4501

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
14 May 2021
Est. completion
31 October 2025

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Recruitment Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov