Brain Cancer Trial, Recruiting NCT04030507 Sponsor: Brigham and Women's Hospital Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT04030507
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with breast cancer that has been confirmed through tissue or cell testing, with the cancer's hormone receptor and HER2 status identified.
  • People whose breast cancer has spread to distant parts of the body (outside the brain) or has come back in a way that cannot be removed by surgery, and who are about to start first or second rounds of chemotherapy for this advanced disease — or people with inflammatory breast cancer being treated with the aim of a cure within six months of diagnosis.
  • People who are 18 years of age or older.
  • People whose doctors estimate they have a life expectancy of more than 12 weeks.
  • People who are willing to take part in all study procedures.
  • Women who could become pregnant must agree to use reliable contraception (such as hormonal methods, barrier methods, or abstinence) throughout the study period.
  • People who are able to understand the study and are willing to sign a written consent form.

Who may not be able to join:

  • People who have a medical reason why they cannot have an MRI scan, such as having a certain type of metal implant in their body that is not safe for MRI.
  • People who have severe kidney disease (stage IV or V) or kidney failure.
  • People who have previously had a severe allergic reaction to the MRI contrast dye called gadolinium.
  • People who are currently pregnant or breastfeeding, as the safety of gadolinium-based contrast agents for a developing baby has not been established.
  • People who have previously been diagnosed with cancer that has spread to the brain.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ayal Aizer, MD, MHS, Brigham and Women's Hospital

Phone: 617-732-7560

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
26 July 2019
Est. completion
1 February 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Neurologic Quality of Life at 12 Months using the MD Anderson Symptom Inventory - Brain Tumor Module; Incidence of Symptomatic Brain Metastases; Incidence of Brain Metastases

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov