Brain Cancer Trial, Recruiting NCT04033497 Sponsor: Brigham and Women's Hospital Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT04033497
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a solid cancer that started outside the brain (confirmed by lab testing of tissue or cell samples) and who have at least one brain metastasis (cancer that has spread to the brain) that was previously treated with a focused form of radiation called stereotactic radiation.
  • People who have a brain lesion (area of abnormal tissue) that has been growing for at least 4 months after stereotactic radiation was delivered to that same spot, and for whom brain surgery to remove the lesion is already planned as part of standard care.
  • People aged 18 years or older.
  • People who are willing to take part in the study procedures.
  • Women who could become pregnant, and men, must agree to use reliable contraception (such as hormonal methods, barrier methods, or abstinence) throughout the study period.
  • People who are able to understand the study and are willing to sign a written consent form (either on paper or electronically).

Who may not be able to join:

  • People for whom MRI scans are not safe — for example, those with certain metal implants that are incompatible with MRI.
  • People with severe or end-stage kidney disease (chronic kidney disease stage 4 or 5, or end-stage renal disease).
  • People who have previously had a severe allergic (anaphylactic) reaction to gadolinium, which is a contrast dye used in MRI scans.
  • Women who are currently pregnant, as the safety of gadolinium-based contrast agents for a developing baby has not been established.
  • Women who are currently breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ayal Aizer, MD, Brigham and Women's Hospital

Phone: 617-732-7560

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
20 August 2019
Est. completion
1 July 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Sensitivity

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov