Phase 2 Migraine Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with migraine with aura (a type of migraine that includes warning symptoms like visual disturbances before the headache)
• You have had at least one migraine with aura per month for the 3 months before joining the trial
• You have not been taking any regular migraine prevention medication for at least 1 month before joining
• If you are a woman who could become pregnant, you must be using a reliable form of contraception starting at least 3 months before the trial and continuing for 1 month after it ends
• You are willing and able to sign a consent form agreeing to take part
• You are covered by French Social Security (confirm with trial site)

Who may not be able to join:

• You have a known allergy or sensitivity to the drug amiloride
• You have high potassium levels in your blood (above 5.5 mmol/l)
• You are currently taking certain other water tablets (diuretics) or potassium supplements that can raise potassium levels
• Your kidneys are not working well enough (below a certain level of function)
• You have severe liver disease
• You are taking certain other medications that may interact with amiloride, including lithium, some blood pressure medicines, ciclosporin, tacrolimus, or certain other drugs (confirm with trial site for the full list)
• You are over 75 years old and have a history of heart or kidney problems
• The trial team feels you may have difficulty following the study procedures
• You are currently pregnant or breastfeeding
• You are under legal guardianship or a similar form of legal protection

Important: Always verify eligibility with the trial site directly before applying.