Chronic Kidney Disease Trial, Recruiting NCT04163614 Sponsor: VA Office of Research and Development Condition: Chronic Kidney Disease
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Chronic Kidney Disease Trial, Recruiting

NCT04163614
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are currently receiving hemodialysis (kidney dialysis treatment)
  • People whose average blood pressure reading before dialysis is above 140 mmHg (the top number) over a 2-week period, OR whose average blood pressure reading after dialysis is above 130 mmHg over a 2-week period

Who may not be able to join:

  • People who have been on hemodialysis for less than 2 months
  • People who are pregnant
  • People whose lowest average blood pressure reading dropped below 95 mmHg (the top number) during the 2-week screening period
  • People whose average blood pressure reading before or after dialysis is above 180 mmHg (the top number)
  • People whose blood pressure regularly drops by more than 60 mmHg from the start to the end of a dialysis session
  • People who routinely take a medication called clonidine during their dialysis sessions
  • People who routinely take a medication called midodrine during their dialysis sessions
  • People who have a documented history of not taking their blood pressure medications as prescribed
  • People whose fluid removal rate during dialysis averaged more than 13 mL per kilogram of body weight per hour during the 2-week screening period
  • For the body fluid measurement part of the study only: people who have had a major limb amputation, people who have an implanted heart device such as a defibrillator or pacemaker, or people who have a metal implant such as a prosthetic joint (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Peter Noel Van Buren, MD, VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX

Phone: (214) 857-2214

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
10 February 2021
Est. completion
1 October 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Ambulatory Systolic Blood Pressure

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov