Phase 2 Chronic Kidney Disease Trial, Recruiting NCT04180085 Sponsor: Nantes University Hospital Condition: Chronic Kidney Disease
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Phase 2 Chronic Kidney Disease Trial, Recruiting

NCT04180085
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who received a heart transplant at least 3 months ago
  • People who are 18 years of age or older
  • People who do not have donor-specific antibodies (proteins that could attack the transplanted heart) at the time of joining the trial
  • People whose kidney function is significantly reduced — either measuring below a certain level, or having dropped by more than half since the time of their heart transplant, and remaining stable for at least 15 days
  • People who received anti-lymphocyte serum as part of their transplant treatment
  • People who have tested positive for the Epstein-Barr virus (a common virus most people have been exposed to)
  • People who have signed a consent form after receiving full information about the trial
  • People of childbearing age who have a negative pregnancy test and agree to use effective contraception throughout the trial and for 6 weeks after it ends
  • People who are able to understand and communicate with the trial team
  • People enrolled in a French Social Security scheme

Who may not be able to join:

  • People who have had a second heart transplant or any other solid organ transplant
  • People with a history of organ rejection
  • People who showed signs of cellular or humoral rejection (immune reactions against the transplanted heart) in a biopsy taken 3 months after their heart transplant
  • People who currently have an active viral infection, such as cytomegalovirus, Epstein-Barr virus, hepatitis C, hepatitis B, or similar viruses
  • People who have tested positive for HIV
  • People currently taking part in another clinical trial
  • People with any medical condition that the trial doctor considers unsafe for participation, such as an ongoing serious infection, a progressing heart complication, or an active cancer
  • People who would be unable to follow the trial procedures as required
  • People who are pregnant or breastfeeding
  • People who are under legal guardianship or a court-ordered protection measure

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 0240087453

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
6 February 2020
Est. completion
1 January 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Clearance

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov