Phase 2 Head and Neck Cancer Trial, Recruiting NCT04214366 Sponsor: Heidelberg University Condition: Head and Neck Cancer
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Phase 2 Head and Neck Cancer Trial, Recruiting

NCT04214366
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a type of cancer called adenoid cystic carcinoma located in the head and neck area, confirmed through a tissue sample (biopsy)
  • People whose cancer meets at least one of these treatment conditions: the tumour cannot be surgically removed, the tumour was not fully removed during surgery, cancer has spread along nerve pathways, or the tumour is classified as a larger/more advanced stage (pT3 or pT4) (confirm with trial site)
  • People who have given their informed written consent to take part
  • People who are reasonably independent in daily self-care, even if normal work or activity is not fully possible — this is measured by a performance score (KI greater than 60% or ECOG 0/1) (confirm with trial site)
  • People aged between 18 and 80 years

Who may not be able to join:

  • People who do not wish to take part in the study
  • People who are unable to give informed consent themselves
  • People whose cancer has spread to distant parts of the body (Stage IV), except for very small lung spots smaller than 1 cm
  • People whose cancer has spread to the lymph nodes, whether detected through scans or confirmed through testing
  • People who have previously had radiotherapy (radiation treatment) to the head and neck area
  • People who have active medical implants — such as a pacemaker or defibrillator — that have not been approved for use with ion radiation therapy at the time of treatment
  • People who cannot have an MRI scan for any reason
  • People who are already taking part in another clinical trial that could affect the results of either study
  • People who are pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Klaus Herfarth, Prof. Dr., University Hospital Heidelberg

Phone: +49 6221 56 8201

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Heidelberg University
Registry
ClinicalTrials.gov
Start date
1 December 2019
Est. completion
1 December 2027

Where this trial is recruiting

🇩🇪 Germany

Primary endpoints

Freedom from loco-regional progression

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov