Phase 2 Uveitis Trial, Completed NCT04222712 Sponsor: Tarsier Pharma Condition: Uveitis
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial (NCT04222712) enrolled 16 people in total, split into two groups of 8 — one group received a lower dose of a treatment called TRS01, and the other received a higher dose. All 16 participants completed the study with no one dropping out. The trial was measuring adverse events, meaning any unwanted or unexpected health experiences that occurred during the study, both in the eyes and throughout the body more broadly. The reported data shows that in the low dose group, 2 out of 8 participants experienced adverse events during the study. In the high dose group, 5 out of 8 participants experienced adverse events. This was the only outcome measure reported in the structured results submitted to ClinicalTrials.gov. No other outcome figures — such as measures of how well the treatment may have worked — were included in the data provided. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 2 Uveitis Trial, Completed

NCT04222712
Completed Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You are able to give your consent to participate, follow instructions, and attend all required appointments for the full length of the study
  • You have been diagnosed with active non-infectious anterior uveitis (inflammation at the front of the eye that is not caused by infection) that needs treatment with steroid eye drops, either starting them for the first time or increasing the dose
  • You have a specific level of eye inflammation (measured by cells in the front chamber of the eye, rated as Grade 2 or Grade 3 — confirm with trial site)
  • Your vision in the eye that is NOT being studied is 20/40 or better (similar to passing a standard driving vision test)
  • If you are able to have children and are sexually active, you are using an adequate form of birth control (specific requirements to be confirmed with trial site)

Who may not be able to join:

  • Your uveitis is caused by an infection
  • You currently have active inflammation of the retina (the light-sensitive layer at the back of the eye)
  • You have cancer or melanoma (a type of skin cancer) that is currently being treated with immunotherapy
  • You are pregnant or breastfeeding
  • You are currently taking certain medications or receiving certain treatments that are not permitted in this study (confirm with trial site for the specific details)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

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Trial details

Status
Completed
Phase
Phase 2
Sponsor
Tarsier Pharma
Registry
ClinicalTrials.gov
Start date
1 February 2020
Est. completion
24 August 2020

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Assessment of Both Systemic and Ocular Adverse Events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov