Obesity Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People with a Body Mass Index (BMI) between 23 and 39.9, or a body fat percentage between 32% and 50%.
• People who are willing to have blood drawn as part of the study.
• People who also have at least one of the following: a fasting blood sugar level between 100 and 125 mg/dL; fasting triglycerides (a type of blood fat) of 125 mg/dL or higher; HDL ("good") cholesterol of 50 mg/dL or lower; a systolic (top number) blood pressure of 130 mmHg or higher, or diastolic (bottom number) blood pressure of 85 mmHg or higher; or a HbA1c (a measure of average blood sugar) between 5.7% and 6.4%.

Who may not be able to join:

• People who are currently taking part in another research study.
• People who have tested positive for COVID-19 in the past 10 days.
• People who have been in close contact with someone who had COVID-19 in the past 14 days.
• People with a systolic (top number) blood pressure of 140 mmHg or higher, or a diastolic (bottom number) blood pressure of 90 mmHg or higher.
• People with LDL ("bad") cholesterol of 190 mg/dL or higher.
• People with triglycerides (a type of blood fat) of 500 mg/dL or higher.
• People who have used tobacco products, e-cigarettes, vaping products, cannabis, or any other nicotine-containing product in the past 6 months.
• People who are currently taking dietary supplements or who are not willing to stop taking them during the study.
• People who follow a vegan or vegetarian diet, or who have any other dietary restrictions, food intolerances, allergies, or sensitivities that would prevent them from eating or drinking the study foods and beverages.
• People who are unwilling to consume the specific foods and beverages provided as part of the study.
• People who drink more than one alcoholic drink per day on a regular basis, or who engage in binge drinking (4 or more drinks within two hours).
• People who are unwilling to avoid alcohol for specific periods required by the study.
• People who consume 400 mg or more of caffeine per day (considered excessive for this study).
• People who are unwilling to avoid caffeine on the days they visit the lab.
• People who have intentionally lost or gained 5% or more of their body weight in the 6 months before joining the study.
• People who have been diagnosed with a disordered eating pattern or an eating disorder.
• People recently diagnosed with, or whose screening blood tests show, anaemia (low haemoglobin), or abnormal liver or thyroid function (confirm with trial site for specific values).
• People with a history of gastric bypass surgery, inflammatory bowel disease (IBD), or other gut conditions that would prevent them from consuming the study foods.
• People with a history of active cancer in the past three years, with the exception of certain minor skin cancers that have been treated by local removal.
• People with recent dental work or mouth conditions that would prevent them from eating or drinking the study foods and beverages.
• People currently taking antipsychotic medications.
• People who have been on long-term antibiotic treatment.
• People currently taking any prescription or over-the-counter medication for high cholesterol, high blood sugar, high blood pressure, weight loss, or conditions that require corticosteroid medicines (such as asthma, arthritis, or eczema).
• People who are pregnant, planning to become pregnant during the study period, or currently breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.