Phase 3 Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are in good general health and able to carry out daily activities with little or no limitation (based on a standard cancer health scoring system called ECOG, scores 0 or 1)
• People who have been diagnosed with a confirmed, early-to-intermediate stage non-small cell lung cancer (Stage II, IIIA, or certain Stage IIIB) that has not yet been treated, based on a specific staging system (8th edition AJCC/UICC)
• People whose lung cancer has been assessed by a chest surgeon as suitable for an operation to remove all of the cancer with the goal of cure
• People who have a tumour tissue sample available for a specific laboratory test (PD-L1 testing) at a central lab
• People whose cancer can be measured on scans according to standard criteria (RECIST v1.1)
• People whose organs (such as liver, kidneys, and blood cells) are functioning at an adequate level
• Women who could become pregnant and men must agree to use contraception or abstain from sex for at least 180 days after the last dose of the study treatment

Who may not be able to join:

• People who have previously received any systemic anti-cancer treatment for lung cancer
• People who have an active, known, or suspected autoimmune disease (a condition where the immune system attacks the body)
• People who have had a different type of cancer within the past 5 years (other than the non-small cell lung cancer being studied)
• People who have a history of, or are suspected to have, lung inflammation (pneumonitis), scarring of the lung tissue (interstitial lung disease), or other serious lung conditions that could affect lung function testing
• People with a significant history of heart or stroke-related disease
• People with a significant history of serious bleeding disorders
• People who have had blood clot or blood vessel-related events (confirm with trial site)
• People who have a known history of HIV infection
• People who have active Hepatitis B or Hepatitis C infection
• People who are allergic to monoclonal antibody medicines or similar protein-based drugs
• People who are allergic to any of the medicines used in this trial
• Women who are pregnant or currently breastfeeding
• People who have a known psychiatric illness or substance abuse disorder
• People who have a confirmed or suspected COVID-19 infection, or who have had close contact with someone with known or suspected COVID-19

Important: Always verify eligibility with the trial site directly before applying.