Obesity Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are between 18 and 50 years old
- People with a body mass index (a measure of body weight relative to height) between 25 and 30, or above 40
- People whose blood lactate levels (a substance produced by the body during physical activity) fall in either the top 25% or bottom 25% of measured ranges (confirm with trial site)
Who may not be able to join:
- People who are pregnant
- People with an intellectual or mental disability
- People who are currently incarcerated
- People who smoke
- People who have been diagnosed with heart disease
- People who have Type 1 or Type 2 diabetes
- People who have a hormonal or endocrine condition (such as a thyroid disorder)
- People who have high blood pressure
- People who have a condition affecting their muscles, bones, or joints
- People who have reduced blood flow in the limbs (peripheral occlusion)
- People who have a liver disease
- People whose body weight has changed by more than 3% in the past 12 months
- People who take medications that affect how the body processes carbohydrates (sugars and starches)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Joseph Houmard, PhD, East Carolina University
Phone: 2527446249
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Carbohydrate/fat oxidation (RER) in the fasting condition.; Muscle oxygen consumption (substrate oxidation) in the fasting condition.; Muscle lactate release in the fasting condition.; Change in Carbohydrate/fat oxidation (RER) in response to glucose + insulin (metabolic flexibility); Change in muscle fat oxidation in response to high fat feeding (metabolic flexibility).; Change in muscle oxygen consumption (substrate oxidation) in response to high fat feeding (metabolic flexibility).
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.