Non-Alcoholic Fatty Liver Disease Trial, Recruiting NCT04366999 Sponsor: Beijing Friendship Hospital Condition: Non-Alcoholic Fatty Liver Disease
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Non-Alcoholic Fatty Liver Disease Trial, Recruiting

NCT04366999
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 16 and 65 years old (any sex)
  • You have been diagnosed with obesity based on World Health Organization guidelines for Asian populations, and you are already scheduled to have weight-loss (bariatric) surgery at one of the participating hospitals
  • You have been found to have fat build-up in your liver, confirmed either by an imaging scan (such as an ultrasound or MRI) or by a tissue sample taken during surgery (this applies to the Base-NAFLD group)
  • You have been diagnosed with a more advanced form of liver disease related to fat build-up (called NASH), confirmed by a liver tissue sample showing a certain level of inflammation and scarring (this applies to the Base-NASH group — confirm details with trial site)

Who may not be able to join:

  • You have had any type of weight-loss (bariatric) surgery in the past
  • You have a history of heavy alcohol use in the past 12 months (more than 30g per day for men, or more than 20g per day for women)
  • You have taken certain medications, including amiodarone, methotrexate, tamoxifen, or long-term steroid medicines (glucocorticoids)
  • You have certain specific medical conditions that can cause fat in the liver, such as a particular type of hepatitis C infection, Wilson's disease, autoimmune hepatitis, or coeliac disease, among others (confirm full list with trial site)
  • You have had major surgery on your stomach or bowel in the past
  • You have been diagnosed with, or are suspected of having, cancer
  • You have a medical or mental health condition that is not well controlled
  • You have a history of other serious medical conditions (confirm specific details with trial site)
  • You are unable or unwilling to understand the study and sign a consent form to take part

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Zhongtao Zhang, M.D.;Ph.D., Beijing Friendship Hospital

Phone: +86-13801060364

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Beijing Friendship Hospital
Registry
ClinicalTrials.gov
Start date
21 April 2020
Est. completion
31 December 2024

Where this trial is recruiting

🇨🇳 China

Primary endpoints

the remisson rate of NAFLD (for Base-NAFLD cohort); Histological remission of NASH without worsening of fibrosis (for Base-NASH cohort)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov