Early Phase 1 Bladder Cancer Trial, Recruiting NCT04369560 Sponsor: Jodi Maranchie Condition: Bladder Cancer
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Early Phase 1 Bladder Cancer Trial, Recruiting

NCT04369560
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 90 years old
  • People who are able to understand and are willing to sign a written consent form
  • People who have a papillary growth in their bladder found during a camera examination (cystoscopy) and are scheduled for a surgical procedure to remove it, OR people who have been confirmed by tissue testing to have muscle-invasive bladder cancer that is contained to the bladder and can be surgically removed with the aim of curing it
  • People who are generally active and able to carry out daily activities with little to no limitation (confirm with trial site)
  • People with kidneys that are working well enough to meet the trial's blood test requirements (confirm with trial site)

Who may not be able to join:

  • People who have had a severe allergic reaction to either of the contrast agents used in this trial (gadobutrol or ferumoxytol)
  • People with severe claustrophobia that would prevent them from completing an MRI scan
  • People who have a medical device, implant, or pacemaker inside their body that is not safe to use with an MRI machine
  • People whose cancer is known or suspected to have spread to other parts of the body
  • Women who are currently pregnant, breastfeeding, or planning to become pregnant
  • People who currently have an untreated urinary tract infection
  • People with a known narrowing of the urethra (the tube that carries urine out of the body) that would prevent a catheter from being inserted
  • People with any other condition that the treating doctor considers to be an unacceptable risk

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Jodi K Maranchie, MD, Associate Professor

Phone: (412) 647-8258

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Jodi Maranchie
Registry
ClinicalTrials.gov
Start date
23 May 2025
Est. completion
30 January 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Accuracy of Magnetic Resonance Imaging assessment of depth of bladder wall penetration to predict pathologic stage determined at tumor resection

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov