Phase 2 Leukaemia Trial, Recruiting NCT04430530 Sponsor: Shenzhen Geno-Immune Medical Institute Condition: Leukaemia
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Phase 2 Leukaemia Trial, Recruiting

NCT04430530
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are older than 6 months of age
  • People who have a B cell blood cancer that has come back after previously receiving a type of treatment that targets a protein called CD19
  • People whose cancer cells carry at least one of the following markers on their surface: CD22, CD123, CD38, CD10, or CD20
  • People who have a general health score above 80 (on a standard scale doctors use to measure how well someone is functioning day-to-day) and are expected to live longer than one month
  • People whose haemoglobin (a measure of red blood cells in the blood) is above 80 g/L
  • People who have no medical reasons preventing the collection of blood cells

Who may not be able to join:

  • People who have other serious active illnesses that would make it difficult for doctors to measure how well the treatment is working
  • People who have a bacterial, fungal, or viral infection that cannot be controlled
  • People who are living with HIV
  • People who have an active hepatitis B (HBV) or hepatitis C (HCV) infection
  • People who are pregnant or currently breastfeeding
  • People who have been taking steroid medications throughout the whole body (such as tablets or injections, not creams) within one week before treatment
  • People who, in the doctors' judgement, would have difficulty participating in ongoing assessments and follow-up visits (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +86 0755-86573763

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shenzhen Geno-Immune Medical Institute
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
31 December 2029

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Safety of fourth generation anti-CD22/CD123/CD38/CD10/CD20 CAR-T cells

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov